scholarly journals Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function

2018 ◽  
Vol 293 (24) ◽  
pp. 9176-9187 ◽  
Author(s):  
Linda S. May-Zhang ◽  
Valery Yermalitsky ◽  
Jiansheng Huang ◽  
Tiffany Pleasent ◽  
Mark S. Borja ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
Structure And Function ◽  
High Density ◽  
And Function

scholarly journals Effect of acylglyceride content on the structure and function of reconstituted high density lipoprotein particles

2001 ◽  
Vol 42 (1) ◽  
pp. 79-87 ◽  
Author(s):  
Sylvie Braschi ◽  
Cynthia R. Coffill ◽  
Tracey A-M. Neville ◽  
Darren M. Hutt ◽  
Daniel L. Sparks
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
Structure And Function ◽  
High Density ◽  
Lipoprotein Particles ◽  
And Function

Structure and function of apolipoprotein A-I and high-density lipoprotein

2000 ◽  
Vol 11 (2) ◽  
pp. 105-115 ◽  
Author(s):  
Jere P. Segrest ◽  
Ling Li ◽  
G. M. Anantharamaiah ◽  
Stephen C. Harvey ◽  
Kalliopi N. Liadaki ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
Structure And Function ◽  
High Density ◽  
Apolipoprotein A ◽  
And Function

High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice

2017 ◽  
Vol 9 (411) ◽  
pp. eaam6084 ◽  
Author(s):  
Sarah E. Heywood ◽  
Adele L. Richart ◽  
Darren C. Henstridge ◽  
Karen Alt ◽  
Helen Kiriazis ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
High Density Lipoprotein ◽  
Glucose Uptake ◽  
Density Lipoprotein ◽  
High Density ◽  
And Function

scholarly journals Novel Insights From Human Studies on the Role of High-Density Lipoprotein in Mortality and Noncardiovascular Disease

2020 ◽  
Author(s):  
Christian M. Madsen ◽  
Anette Varbo ◽  
Børge G. Nordestgaard
Keyword(s):  
Cardiovascular Disease ◽  
High Density Lipoprotein ◽  
Therapeutic Potential ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Cancer Type ◽  
Health And Disease ◽  
And Function

The vast majority of research about HDL (high-density lipoprotein) has for decades revolved around the possible role of HDL in atherosclerosis and its therapeutic potential within cardiovascular disease prevention; however, failures with therapies aimed at increasing HDL cholesterol has left questions as to what the role and function of HDL in human health and disease is. Recent observational studies have further shown that extreme high HDL cholesterol is associated with high mortality leading to speculations that HDL could in some instances be harmful. In addition, evidence from observational, and to a lesser extent genetic, studies has emerged indicating that HDL might be associated with the development of other major noncardiovascular diseases, such as infectious disease, autoimmune disease, cancer, type 2 diabetes, kidney disease, and lung disease. In this review, we discuss (1) the association between extreme high HDL cholesterol and mortality and (2) the emerging human evidence linking HDL to several major diseases outside the realm of cardiovascular disease.

Gene Therapy to Improve High-Density Lipoprotein Metabolism and Function

2010 ◽  
Vol 16 (13) ◽  
pp. 1531-1544 ◽  
Author(s):  
Eline Van Craeyveld ◽  
Stephanie Gordts ◽  
Frank Jacobs ◽  
Bart De Geest
Keyword(s):  
Gene Therapy ◽  
High Density Lipoprotein ◽  
Lipoprotein Metabolism ◽  
Density Lipoprotein ◽  
High Density ◽  
And Function
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