Effect of essential oil obtained from Croton cajucara Benth. on gastric ulcer healing and protective factors of the gastric mucosa

Phytomedicine ◽  
2002 ◽  
Vol 9 (6) ◽  
pp. 523-529 ◽  
Author(s):  
C.A. Hiruma-Lima ◽  
J.S. Gracioso ◽  
E.J.B. Bighetti ◽  
D.M. Grassi-Kassisse ◽  
D.S. Nunes ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Essential Oil ◽  
Protective Factors ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing ◽  
Croton Cajucara

The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity

2021 ◽  
Vol 271 ◽  
pp. 113832
Author(s):  
Gabriela Bueno ◽  
Stefanni Liliane Chavez Rico ◽  
Larissa Lucena Périco ◽  
Rie Ohara ◽  
Vinicius Peixoto Rodrigues ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Essential Oil ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing ◽  
Baccharis Trimera

Reduction of EGF is associated with the delay of ulcer healing by cigarette smoking

2000 ◽  
Vol 278 (1) ◽  
pp. G10-G17 ◽  
Author(s):  
L. Ma ◽  
W. P. Wang ◽  
J. Y. C. Chow ◽  
S. T. Yuen ◽  
C. H. Cho
Keyword(s):  
Cell Proliferation ◽  
Gastric Ulcer ◽  
Growth Factor ◽  
Gastric Mucosa ◽  
Cigarette Smoking ◽  
Mrna Expression ◽  
Salivary Glands ◽  
Cigarette Smoke ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing

Cigarette smoking is associated with peptic ulcer diseases. Smokers have lower levels of salivary epidermal growth factor (EGF) than nonsmokers. We investigated whether reduction of EGF is involved in the delay of gastric ulcer healing by cigarette smoking. Rats with acetic acid-induced ulcers were exposed to cigarette smoke (0, 2, or 4% vol/vol) 1 day after ulcer induction. EGF level was elevated 1 day after ulcer induction in salivary glands and serum, and 4 days after ulcer induction in the gastric mucosa. However, cigarette smoke depressed these beneficial effects and EGF mRNA expression in salivary glands and gastric mucosa. Cigarette smoke delayed gastric ulcer healing and reduced cell proliferation, angiogenesis, and mucus synthesis. Exogenous EGF (10 and 20 μg/kg iv) before smoke exposure reversed the adverse effects of cigarette smoke, whereas vascular endothelial growth factor level and nitric oxide synthase activity were unaffected. It is concluded that the detrimental effect of cigarette smoke on ulcer healing is a consequence of reduction of angiogenesis, cell proliferation, and mucus secretion through the depressive action on EGF biosynthesis and its mRNA expression in salivary glands and gastric mucosa.

scholarly journals Age-Related Changes in the Expression of Heat Shock Protein 70 and 90 on the Gastric Mucosa During Gastric Ulcer Healing

2018 ◽  
Vol 6 (5) ◽  
pp. 01 ◽  
Author(s):  
Ajayi Ayodeji Folorunsho ◽  
Aniviye Blessing Oluwafunke ◽  
Kehinde Busuyi David ◽  
Akintola Adebola Olayemi
Keyword(s):  
Gastric Ulcer ◽  
Heat Shock ◽  
Gastric Mucosa ◽  
Heat Shock Protein ◽  
Ulcer Healing ◽  
Heat Shock Protein 70 ◽  
Gastric Ulcer Healing ◽  
Age Related ◽  
Age Related Changes

Gastric ulcer healing is regulated by platelets through endostatin release: Modulation by ticlopidine, aspirin and celecoxib

2001 ◽  
Vol 120 (5) ◽  
pp. A143-A143
Author(s):  
L MA ◽  
S ELLIOTT ◽  
G CIRINO ◽  
A BURET ◽  
J WALLACE
Keyword(s):  
Gastric Ulcer ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing

Gastric ulcer healing is regulated by platelets through endostatin release: Modulation by ticlopidine, aspirin and celecoxib

2001 ◽  
Vol 120 (5) ◽  
pp. A143
Author(s):  
Li Ma ◽  
Susan N. Elliott ◽  
Giuseppe Cirino ◽  
Andre Buret ◽  
John L. Wallace
Keyword(s):  
Gastric Ulcer ◽  
Ulcer Healing ◽  
Gastric Ulcer Healing

Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors

2002 ◽  
Vol 442 (1-2) ◽  
pp. 125-135 ◽  
Author(s):  
Bettina Berenguer ◽  
Catalina Alarcón de la Lastra ◽  
Francisco Javier Moreno ◽  
Maria José Martı́n
Keyword(s):  
Gastric Ulcer ◽  
Ulcer Healing ◽  
Cyclooxygenase 2 ◽  
Chronic Gastric Ulcer ◽  
Gastric Ulcer Healing ◽  
Cyclooxygenase 2 Inhibitors
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