Detection of Mutations in RNA Polymerase Beta Subunit Gene Encoding Resistance to Rifampin inMycobacterium tuberculosisby DNA Microarray

2005 ◽  
Vol 38 (13) ◽  
pp. 2117-2134
Author(s):  
Mengsu Yang ◽  
Pui Yan Tsoi ◽  
Cheuk‐Wing Li ◽  
Hok Sin Woo ◽  
Jianlong Zhao ◽  
...  
2015 ◽  
Vol 46 (2) ◽  
pp. 465-476 ◽  
Author(s):  
Lenice Roteia Cardoso Jung ◽  
Maria Rosa Quaresma Bomfim ◽  
Erna Geessien Kroon ◽  
Álvaro Cantini Nunes

2020 ◽  
Vol 77 (10) ◽  
pp. 2933-2939
Author(s):  
Keiichiro Mukai ◽  
Momoko Kobayashi ◽  
Kanata Hoshino ◽  
Tomoko Maruyama ◽  
Daiki Hayashi ◽  
...  

1993 ◽  
Vol 268 (4) ◽  
pp. 2749-2754
Author(s):  
F.E. Wondisford ◽  
H.J. Steinfelder ◽  
M. Nations ◽  
S. Radovick

1982 ◽  
Vol 152 (2) ◽  
pp. 736-746
Author(s):  
S P Ridley ◽  
M P Oeschger

An Escherichia coli strain carrying an amber mutation (UAG) in rpoC, the gene encoding the beta prime subunit of RNA polymerase, was isolated after mutagenesis with nitrosoguanidine. The mutation was moved into an unmutagenized strain carrying the supD43,74 allele, which encodes a temperature-sensitive su1 amber suppressor, and sue alleles, which enhance the efficiency of the suppressor. In this background, beta prime is not synthesized at high temperature. Suppression of the mutation by the non-temperature-sensitive amber suppressor su1+ yields a protein which is functional at all temperatures examined (30, 37, and 42 degrees C).


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