Bioluminescent Flow Sensors: L-Alanine Determination in Serum and Urine

1987 ◽  
Vol 20 (8) ◽  
pp. 1315-1330 ◽  
Author(s):  
S. Girotti ◽  
A. Roda ◽  
S. Piazzi ◽  
G. Carrea ◽  
A. L. Piacentini ◽  
...  
Keyword(s):  
Flow Sensors ◽  
Serum And Urine

Structured methods for improving flow measurement accuracy in pipelines

2020 ◽  
pp. 30-35
Author(s):  
Gurami N. Akhobadze
Keyword(s):  
Flow Measurement ◽  
Measurement Accuracy ◽  
Directional Coupler ◽  
Signal To Noise Ratio ◽  
Scattered Wave ◽  
Orthogonal Polarization ◽  
Flow Sensors ◽  
Information Signal ◽  
Mass Flows ◽  
Processing Device

In the age of digital transformation of production processes in industry and science the development and design of intelligent flow sensors for granular and liquid substances transferring through pipelines becomes more important. With this in view new approaches for improving the accuracy of microwave flowmeters are proposed. Taking into account the characteristics ofelectromagnetic waves propagating through a pipeline, a wave scattered by inhomogeneities of the controlled medium is analyzed. Features of the transformation of the polarized scattered wave limiting the geometric dimensions of the pipeline and optimizing the values of the useful scattered signal are revealed. Expediency of collection of the information signal with orthogonal polarization of the scattered wave and through a directional coupler is substantiated. The method of estimating the measurement accuracy with reference to the signal-to-noise ratio at the input of the processing device is given. The research results can be used in cryogenic machine engineering to measure volume and mass flows of liquid cryogenic products.

Stimulation of residual insulin secretion by glibenclamide in insulin dependent diabetics

1980 ◽  
Vol 95 (3) ◽  
pp. 372-375 ◽  
Author(s):  
B. J. Burke ◽  
R. J. Sherriff
Keyword(s):  
Insulin Secretion ◽  
Insulin Therapy ◽  
Metabolic Control ◽  
C Peptide ◽  
Beneficial Effects ◽  
Insulin Dependent ◽  
Serum And Urine ◽  
Stimulation Of

Abstract. Residual insulin secretion, reflected by the presence of C-peptide in serum and urine, has been demonstrated in 5 of 10 insulin-requiring diabetics of less than 10 years' duration tested. The C-peptide response, in the C-peptide secretors, showed a significant increase in both serum and urine after 4 weeks' treatment with 15 mg glibenclamide daily in addition to their usual insulin regime although no beneficial effects in metabolic control were detected. It is suggested that glibenclamide might be a useful adjunct to insulin therapy in insulinrequiring diabetics who still secrete C-peptide.

NS1 glycoprotein detection in serum and urine as an electrochemical screening immunosensor for dengue and Zika virus

2021 ◽  
Author(s):  
Priscila D. Mendonça ◽  
Lorenna K. B. Santos ◽  
Marcos V. Foguel ◽  
Marco A. B. Rodrigues ◽  
Marli T. Cordeiro ◽  
...  
Keyword(s):  
Zika Virus ◽  
Serum And Urine

Urinary gonadotropin measurements by enhanced luminometric assays (LIA) for the evaluation of pubertal development

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
And Demir ◽  
Adem Aydın ◽  
Atilla Büyükgebiz ◽  
Ulf-Håkan Stenman ◽  
Matti Hero
Keyword(s):  
Healthy Subjects ◽  
Reliable Method ◽  
Pubertal Development ◽  
High Sensitivity ◽  
Tanner Stage ◽  
Time Resolved ◽  
Stage 1 ◽  
Sensitive Detection Technique ◽  
Serum And Urine

Abstract Objectives Determination of LH in urine has proved to be a reliable method for evaluation of pubertal development. The human LH assay based on time-resolved immunofluorometric (IFMA) technology (AutoDELFIA, PerkinElmer, Wallac) has been found to be suitable for this purpose thanks to its high sensitivity but other assays have not been evaluated. We have analyzed our data obtained by another potentially sensitive detection technique, enhanced luminometric assay (LIA) with the objective of finding a viable alternative to IFMA since these may not be available in the future. Methods LIA was used to measure LH and FSH in serum and urine samples from 100 healthy subjects of each Tanner stage and both genders, whose pubertal development has been determined. Results Urinary gonodotropin concentrations measured by LIA correlated well with Tanner stage [(r=0.93 for girls, r=0.81 for boys; p<0.01 for LH) and (r=0.81 for girls, r=0.73 for boys; p<0.01 for FSH)]. LIA determinations revealed the increase in U-LH concentrations during the transition from Tanner stage 1–2 in both girls and boys (p<0.001), whereas U-FSH and S-LH were able to detect the increase from Tanner stage 1–2 only in boys or girls, respectively (both p<0.001). Conclusions Measurement of urinary gonadotropin concentrations by LIA may be useful for the evaluation of overall pubertal development and also in the detection of transition from prepuberty to puberty.

scholarly journals Integrated impedance sensing of liquid sample plug flow enables automated high throughput NMR spectroscopy

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Omar Nassar ◽  
Mazin Jouda ◽  
Michael Rapp ◽  
Dario Mager ◽  
Jan G. Korvink ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
High Throughput ◽  
Plug Flow ◽  
Microfluidic System ◽  
High Resolution Spectroscopy ◽  
Dead Volume ◽  
Absolute Difference ◽  
Immiscible Fluid ◽  
Flow Sensors ◽  
Novel Approach

AbstractA novel approach for automated high throughput NMR spectroscopy with improved mass-sensitivity is accomplished by integrating microfluidic technologies and micro-NMR resonators. A flow system is utilized to transport a sample of interest from outside the NMR magnet through the NMR detector, circumventing the relatively vast dead volume in the supplying tube by loading a series of individual sample plugs separated by an immiscible fluid. This dual-phase flow demands a real-time robust sensing system to track the sample position and velocities and synchronize the NMR acquisition. In this contribution, we describe an NMR probe head that possesses a microfluidic system featuring: (i) a micro saddle coil for NMR spectroscopy and (ii) a pair of interdigitated capacitive sensors flanking the NMR detector for continuous position and velocity monitoring of the plugs with respect to the NMR detector. The system was successfully tested for automating flow-based measurement in a 500 MHz NMR system, enabling high resolution spectroscopy and NMR sensitivity of 2.18 nmol s1/2 with the flow sensors in operation. The flow sensors featured sensitivity to an absolute difference of 0.2 in relative permittivity, enabling distinction between most common solvents. It was demonstrated that a fully automated NMR measurement of nine individual 120 μL samples could be done within 3.6 min or effectively 15.3 s per sample.

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