Inhibition by pentamidine isethionate of the NADPH-oxidase system of human neutrophilic granulocytes

1989 ◽  
Vol 83 (6) ◽  
pp. 643-644
Author(s):  
M. A. Arnott ◽  
J. Hay
PEDIATRICS ◽  
1991 ◽  
Vol 88 (1) ◽  
pp. 183-185
Author(s):  
SHIGENOBU UMEKI

To the Editor.— Such phagocytic cells as neutrophils and macrophages are crucial elements in the host defense against bacterial [See table in the PDF file] and fungal infections. Microbicidal activity depends to a large extent on NADPH oxidase system, which can be activated by stimuli (bacteria, fungi) and which generates the superoxide anion and other highly reactive forms of reduced oxygen.1,2 The neutrophil NADPH oxidase system is composed functionally of membrane-bound catalytic components (which consist of at least two constituents, the low potential cytochrome b5583-5 and flavoprotein5) and soluble cytosolic components6,7 which participate as either catalytic or regulatory elements.


2003 ◽  
Vol 125 (40) ◽  
pp. 12112-12113 ◽  
Author(s):  
Henk-Jan van Manen ◽  
Natallia Uzunbajakava ◽  
Robin van Bruggen ◽  
Dirk Roos ◽  
Cees Otto

2006 ◽  
Vol 902 (1) ◽  
pp. 241-248 ◽  
Author(s):  
MITSUHIRO YOKOYAMA ◽  
NOBUTAKA INOUE ◽  
SEINOSUKE KAWASHIMA
Keyword(s):  

2013 ◽  
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pp. 927-935 ◽  
Author(s):  
Ana Baltanás ◽  
Maria E. Solesio ◽  
Guillermo Zalba ◽  
María F. Galindo ◽  
Ana Fortuño ◽  
...  

2007 ◽  
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Author(s):  
Nobuhiro Suematsu ◽  
Caroline Ojaimi ◽  
Pawel M Kaminski ◽  
Zipping Wang ◽  
Xiaobin Xu ◽  
...  

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e47738 ◽  
Author(s):  
Sunil Joshi ◽  
Benjamin T. Saylor ◽  
Wei Wang ◽  
Ammon B. Peck ◽  
Saeed R. Khan

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