Approximation preserving reductions for set covering, vertex covering and independent set hierarchies under differential approximationa

2004 ◽  
Vol 81 (5) ◽  
pp. 569-582
Author(s):  
Tinaz Ekim* ◽  
Vangelis Th. Paschos
Mathematics ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 49
Author(s):  
Eman AbuHijleh ◽  
Mohammad Abudayah ◽  
Omar Alomari ◽  
Hasan Al-Ezeh

Graph invariants are the properties of graphs that do not change under graph isomorphisms, the independent set decision problem, vertex covering problem, and matching number problem are known to be NP-Hard, and hence it is not believed that there are efficient algorithms for solving them. In this paper, the graph invariants matching number, vertex covering number, and independence number for the zero-divisor graph over the rings Z p k and Z p k q r are determined in terms of the sets S p i and S p i q j respectively. Accordingly, a formula in terms of p , q , k , and r, with n = p k , n = p k q r is provided.


Complexity ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-29 ◽  
Author(s):  
Pablo Adasme ◽  
Ali Dehghan Firoozabadi

Let Gd=V,Ed be an input disk graph with a set of facility nodes V and a set of edges Ed connecting facilities in V. In this paper, we minimize the total connection cost distances between a set of customers and a subset of facility nodes S⊆V and among facilities in S, subject to the condition that nodes in S simultaneously form a spanning tree and an independent set according to graphs G¯d and Gd, respectively, where G¯d is the complement of Gd. Four compact polynomial formulations are proposed based on classical and set covering p-Median formulations. However, the tree to be formed with S is modelled with Miller–Tucker–Zemlin (MTZ) and path orienteering constraints. Example domains where the proposed models can be applied include complex wireless and wired network communications, warehouse facility location, electrical power systems, water supply networks, and transportation networks, to name a few. The proposed models are further strengthened with clique valid inequalities which can be obtained in polynomial time for disk graphs. Finally, we propose Kruskal-based heuristics and metaheuristics based on guided local search and simulated annealing strategies. Our numerical results indicate that only the MTZ constrained models allow obtaining optimal solutions for instances with up to 200 nodes and 1000 users. In particular, tight lower bounds are obtained with all linear relaxations, e.g., less than 6% for most of the instances compared to the optimal solutions. In general, the MTZ constrained models outperform path orienteering ones. However, the proposed heuristics and metaheuristics allow obtaining near-optimal solutions in significantly short CPU time and tight feasible solutions for large instances of the problem.


2019 ◽  
Vol 29 (1) ◽  
pp. 7-14
Author(s):  
Aleksandr N. Maksimenko

Abstract In 1995 T. Matsui considered a special family of 0/1-polytopes with an NP-complete criterion for vertex nonadjacency relation. In 2012 the author demonstrated that all polytopes of this family appear as faces of polytopes associated with the following NP-complete problems: the travelling salesman problem, the 3-satisfiability problem, the knapsack problem, the set covering problem, the partial ordering problem, the cube subgraph problem, and some others. Here it is shown that none of the polytopes of the aforementioned special family (with the exception of the one-dimensional segment) can appear as a face in a polytope associated with the problem of the maximum independent set, the set packing problem, the set partitioning problem, and the problem of 3-assignments.


2020 ◽  
Vol 25 (40) ◽  
pp. 4296-4302 ◽  
Author(s):  
Yuan Zhang ◽  
Zhenyan Han ◽  
Qian Gao ◽  
Xiaoyi Bai ◽  
Chi Zhang ◽  
...  

Background: β thalassemia is a common monogenic genetic disease that is very harmful to human health. The disease arises is due to the deletion of or defects in β-globin, which reduces synthesis of the β-globin chain, resulting in a relatively excess number of α-chains. The formation of inclusion bodies deposited on the cell membrane causes a decrease in the ability of red blood cells to deform and a group of hereditary haemolytic diseases caused by massive destruction in the spleen. Methods: In this work, machine learning algorithms were employed to build a prediction model for inhibitors against K562 based on 117 inhibitors and 190 non-inhibitors. Results: The overall accuracy (ACC) of a 10-fold cross-validation test and an independent set test using Adaboost were 83.1% and 78.0%, respectively, surpassing Bayes Net, Random Forest, Random Tree, C4.5, SVM, KNN and Bagging. Conclusion: This study indicated that Adaboost could be applied to build a learning model in the prediction of inhibitors against K526 cells.


2020 ◽  
Vol 15 ◽  
Author(s):  
Chun Qiu ◽  
Sai Li ◽  
Shenghui Yang ◽  
Lin Wang ◽  
Aihui Zeng ◽  
...  

Aim: To search the genes related to the mechanisms of the occurrence of glioma and to try to build a prediction model for glioblastomas. Background: The morbidity and mortality of glioblastomas are very high, which seriously endangers human health. At present, the goals of many investigations on gliomas are mainly to understand the cause and mechanism of these tumors at the molecular level and to explore clinical diagnosis and treatment methods. However, there is no effective early diagnosis method for this disease, and there are no effective prevention, diagnosis or treatment measures. Methods: First, the gene expression profiles derived from GEO were downloaded. Then, differentially expressed genes (DEGs) in the disease samples and the control samples were identified. After that, GO and KEGG enrichment analyses of DEGs were performed by DAVID. Furthermore, the correlation-based feature subset (CFS) method was applied to the selection of key DEGs. In addition, the classification model between the glioblastoma samples and the controls was built by an Support Vector Machine (SVM) based on selected key genes. Results and Discussion: Thirty-six DEGs, including 17 upregulated and 19 downregulated genes, were selected as the feature genes to build the classification model between the glioma samples and the control samples by the CFS method. The accuracy of the classification model by using a 10-fold cross-validation test and independent set test was 76.25% and 70.3%, respectively. In addition, PPP2R2B and CYBB can also be found in the top 5 hub genes screened by the protein– protein interaction (PPI) network. Conclusions: This study indicated that the CFS method is a useful tool to identify key genes in glioblastomas. In addition, we also predicted that genes such as PPP2R2B and CYBB might be potential biomarkers for the diagnosis of glioblastomas.


Mathematics ◽  
2021 ◽  
Vol 9 (16) ◽  
pp. 1839
Author(s):  
Broderick Crawford ◽  
Ricardo Soto ◽  
José Lemus-Romani ◽  
Marcelo Becerra-Rozas ◽  
José M. Lanza-Gutiérrez ◽  
...  

One of the central issues that must be resolved for a metaheuristic optimization process to work well is the dilemma of the balance between exploration and exploitation. The metaheuristics (MH) that achieved this balance can be called balanced MH, where a Q-Learning (QL) integration framework was proposed for the selection of metaheuristic operators conducive to this balance, particularly the selection of binarization schemes when a continuous metaheuristic solves binary combinatorial problems. In this work the use of this framework is extended to other recent metaheuristics, demonstrating that the integration of QL in the selection of operators improves the exploration-exploitation balance. Specifically, the Whale Optimization Algorithm and the Sine-Cosine Algorithm are tested by solving the Set Covering Problem, showing statistical improvements in this balance and in the quality of the solutions.


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