Natural History of Hyperlactataemia in Human Immunodeficiency Virus-1-infected Patients During Highly Active Antiretroviral Therapy

2003 ◽  
Vol 35 (1) ◽  
pp. 62-66 ◽  
Author(s):  
TUAN K. HUYNH ◽  
HANS R. LÜTTICHAU ◽  
BIRGIT T. ROGE ◽  
JAN GERSTOFT
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Natural History ◽  
Highly Active Antiretroviral Therapy ◽  
Highly Active ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Human Immunodeficiency Virus 1

scholarly journals Malignancies, Particularly B-Cell Lymphomas, Are a Frequent Cause of Mortality in Human Immunodeficiency Virus-1 Patients Despite Highly Active Antiretroviral Therapy

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Daniel O. Griffin ◽  
Michael Metzger ◽  
Kaitlin Poeth ◽  
Kathy Deng ◽  
Arif Dharsee ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
B Cell ◽  
Highly Active Antiretroviral Therapy ◽  
B Cell Lymphomas ◽  
Highly Active ◽  
Immunodeficiency Virus ◽  
Hiv 1 ◽  
Human Immunodeficiency Virus 1 ◽  
Hiv Negative

Abstract Human immunodeficiency virus (HIV)-1-infected individuals are affected by diseases at rates above those of their HIV-negative peers despite the increased life expectancy of the highly active antiretroviral therapy era. We followed a cohort of approximately 2000 HIV-1-infected patients for 5 years. The most frequent cause of death in this HIV-1-infected cohort was malignancy, with 39% of all classified deaths due to cancer. Among the cancer deaths, B-cell lymphomas were the most commonly seen malignancy, representing 34% of all cancer deaths. These lymphomas were very aggressive with a median survival of <2 months from time of diagnosis.

scholarly journals Synchronous and metachronous malignant melanomas arising in a human immunodeficiency virus-positive patient after the commencement of highly active antiretroviral therapy treatment: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Sharad P. Paul ◽  
Simon Briggs ◽  
Michael Hitchcock
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Previous History ◽  
Case Presentation ◽  
Highly Active ◽  
Immunodeficiency Virus ◽  
History Of

Abstract Background We present an unusual case of a patient who developed four melanomas within a few months of diagnosis with human immunodeficiency virus and commencement of highly active antiretroviral therapy therapy. The patient had no previous history of melanoma, and previous skin checks were normal. Case presentation A 50-year-old Caucasian male drainlayer with Fitzpatrick type 2 skin presented for a routine skin examination. He had been diagnosed with human immunodeficiency virus 4 months earlier and commenced on highly active antiretroviral therapy therapy. He was found to have three melanomas (melanoma in situ stage) on excision biopsies, and when he presented for wider excisions of these sites a few weeks later, another new melanoma in situ was found. He had no other medical history of note, and no symptoms to report. He is being followed up 3-monthly. Conclusions This case of a human immunodeficiency virus-positive person presenting with four cutaneous melanomas—occurring in both synchronous and metachronous fashion within a 4-month period—is being presented both for its uniqueness and also to highlight the increased need for close skin surveillance in human immunodeficiency virus-positive patients.

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