Preparation and characterization of hCG-loaded polylactide or poly(lactide-co-glycolide) microspheres using a modified water-in-oil-in-water (w/o/w) emulsion solvent evaporation technique

2001 ◽  
Vol 18 (2) ◽  
pp. 247-260 ◽  
Author(s):  
K. J. Zhu, H. L. Jiang, X. Y. Du, J
Keyword(s):  
Solvent Evaporation ◽  
Oil In Water ◽  
Evaporation Technique

Synthesis and Characterization of Magnetic Polymeric Nanospheres for Biomedical Applications

2002 ◽  
Vol 750 ◽  
Author(s):  
D. K. Kim ◽  
M. Mikhaylova ◽  
M. Toprak ◽  
A. Guyou ◽  
Y. K. Jeong ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Polymeric Nanoparticles ◽  
Oil Emulsion ◽  
Diffusion Technique ◽  
Oil In Water ◽  
Anti Cancer ◽  
Evaporation Technique ◽  
Water In Oil Emulsion ◽  
Polymeric Nanospheres

ABSTRACTEntrapment of proteins in biodegradable nanospheres has been widely investigated as a technique to produce sustained release formulations for protein or anti-cancer drugs administration. Amphiphilic PLLA-mPEG diblock copolymer was prepared by ring opening polymerization (ROP) to form polymeric nanoparticles with a core-shell structure. The main encapsulation technique done is a water-in-oil-in-water (w/o/w) solvent evaporation technique. Here, protein was encapsulated using a newly developed water-in-oil emulsion-solvent diffusion technique. This technique leads to the formation of an emulsion combined with the immediate precipitation of the PLLA-mPEG. This phenomenon is caused by the diffusion of the polymer solvent to an external organic phase.

Crystal growth and characterization of CuI single crystals by solvent evaporation technique

2010 ◽  
Vol 45 (5) ◽  
pp. 636-639 ◽  
Author(s):  
Mu Gu ◽  
Pan Gao ◽  
Xiao-Lin Liu ◽  
Shi-Ming Huang ◽  
Bo Liu ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Single Crystals ◽  
Solvent Evaporation ◽  
Evaporation Technique

Preparation and Characterization of Poly(D,L-Lactide) and Silk Fibroin Nanocomposite Microparticles for Potential Use in Tissue Engineering

2008 ◽  
Vol 55-57 ◽  
pp. 725-728
Author(s):  
N. Kotsaeng ◽  
Y. Srisuwan ◽  
Y. Baimark ◽  
N. Narkkong ◽  
W. Simchuer
Keyword(s):  
Surface Roughness ◽  
Silk Fibroin ◽  
Vacuum Oven ◽  
Oil In Water ◽  
Evaporation Technique ◽  
Ft Ir ◽  
Emulsification Solvent Evaporation ◽  
Potential Use ◽  
Nanocomposite Microparticles

Nanocomposite poly(D,L-lactide) (PDLL)-based microparticles containing silk fibroin (SF) nanoparticles were prepared by oil-in-water emulsification solvent evaporation technique of PDLL/SF nanocomposite. The PDLL/SF nanocomposite was obtained from nanoprecipitating SF into PDLL solution in acetone before dried in vacuum oven. The nanocomposite microparticles with PDLL/SF ratios of 20/1, 10/1 and 5/1 (w/w) were prepared and investigated. Interactions between PDLL and SF of microparticles can be observed from FT-IR and thermogravimetric results. Sizes of the SF nanoparticles and the nanocomposite microparticles from SEM micrographs were in the ranges of 50-500 nm and 50-200 µm, respectively. The sizes of SF nanoparticles and nanocomposite microparticles increased as increasing the SF ratio. Surface roughness of the resulted microparticles also increased with the SF ratio.

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