MR imaging of pituitary macroadenomas before and after transsphenoidal surgery

MR findings before and after transsphenoidal surgery were evaluated in 6 cases. T1-weighted (TR/TE 600/20) sagittal and coronal images with 2 or 4 acquisitions were obtained, using 3-mm slice thickness and 0.3-mm interslice gaps. Of 18 MR examinations, 13 included coronal i.v. contrast medium enhanced images. Image quality, sinus cavernosus invasion, identification of normal pituitary tissue and tumor size were examined. All MR studies clearly demonstrated the macroadenomas whether 2 or 4 acquisitions were used, and whether i.v. contrast medium was administered or not. Surgically confirmed sinus cavernosus infiltration was seen in 4 patients. The pituitary stalk was identified separate from the tumor in 2 patients, and the gland in one. There was reduction in tumor size over time, indicating that final radiologic assessment after transsphenoidal surgery is best performed 4 to 6 months postoperatively. It should not be necessary to routinely include i.v. contrast medium injection in the postoperative evaluation of macroadenomas.

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Gd-Dtpa-Enhanced Mr Imaging of Pituitary Macroadenomas

Acta Radiologica ◽

10.1177/028418519203300408 ◽

1992 ◽

Vol 33 (4) ◽

pp. 323-332 ◽

Cited By ~ 8

Author(s):

P. Lundin ◽

K. Bergström

Keyword(s):

Mr Imaging ◽

Post Contrast ◽

Additional Information ◽

Tumour Extension ◽

Adjacent Structures ◽

Before And After ◽

Operative Evaluation ◽

Dual Echo ◽

Pituitary Macroadenomas ◽

T2 Weighted Images

In a study comprising 40 patients with pituitary macroadenomas, MR imaging was performed before and after administration of Gd-DTPA. Before contrast administration T1- and T2-weighted images were obtained, and after the injection, frontal and/or sagittal T1-weighted images. Tumour extension and delineation, relationship to adjacent structures, and signal intensity patterns were evaluated. Compared with pre-contrast T1-weighted images only, post-contrast images provided considerable additional information, but not infrequently this information could also be extracted from pre-contrast T2-weighted images. Post-contrast images were superior regarding the tumour relationship to the cavernous sinus and to the normal pituitary tissue. T2-weighted images were helpful in the diagnosis of degenerative changes, in particular intratumoural haemorrhage. A positive correlation was found between the T2 value (from dual echo sequences) and the degree of enhancement in areas with an appearance of solid tumour tissue, and the enhancement was significantly lower in GH-secreting tumours than in non-secreting ones. It is concluded that the use of Gd-DTPA is often justified in pituitary macroadenomas, particularly in pre-operative evaluation.

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Intraoperative MRI during transsphenoidal surgery of pituitary macroadenomas

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-2006-932940 ◽

2006 ◽

Vol 114 (S 1) ◽

Author(s):

B von Keller ◽

O Ganslandt ◽

R Fahlbusch ◽

M Buchfelder ◽

C Nimsky

Keyword(s):

Transsphenoidal Surgery ◽

Intraoperative Mri ◽

Pituitary Macroadenomas

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Gd-DTPA-Enhanced MR Imaging of Pituitary Macroadenomas

Acta Radiologica ◽

10.3109/02841859209173187 ◽

1992 ◽

Vol 33 (4) ◽

pp. 323-332 ◽

Cited By ~ 1

Author(s):

P. Lundin ◽

K. Bergstrom

Keyword(s):

Mr Imaging ◽

Pituitary Macroadenomas

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Faculty Opinions recommendation of Articular cartilage MR imaging and thickness mapping of a loaded knee joint before and after meniscectomy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1098083.554062 ◽

2007 ◽

Author(s):

Sharmila Majumdar

Keyword(s):

Articular Cartilage ◽

Mr Imaging ◽

Knee Joint ◽

Before And After

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Audio-guided self-hypnosis for reduction of claustrophobia during MR imaging: results of an observational 2-group study

European Radiology ◽

10.1007/s00330-021-07887-w ◽

2021 ◽

Author(s):

Adriane E. Napp ◽

Torsten Diekhoff ◽

Olf Stoiber ◽

Judith Enders ◽

Gerd Diederichs ◽

...

Keyword(s):

High Risk ◽

Mr Imaging ◽

Odds Ratio ◽

Control Group ◽

Waiting Room ◽

High Risk Patients ◽

Imaging Results ◽

Before And After ◽

Risk Patients ◽

And Coping

Abstract Objectives To evaluate the influence of audio-guided self-hypnosis on claustrophobia in a high-risk cohort undergoing magnetic resonance (MR) imaging. Methods In this prospective observational 2-group study, 55 patients (69% female, mean age 53.6 ± 13.9) used self-hypnosis directly before imaging. Claustrophobia included premature termination, sedation, and coping actions. The claustrophobia questionnaire (CLQ) was completed before self-hypnosis and after MR imaging. Results were compared to a control cohort of 89 patients examined on the same open MR scanner using logistic regression for multivariate analysis. Furthermore, patients were asked about their preferences for future imaging. Results There was significantly fewer claustrophobia in the self-hypnosis group (16%; 9/55), compared with the control group (43%; 38/89; odds ratio .14; p = .001). Self-hypnosis patients also needed less sedation (2% vs 16%; 1/55 vs 14/89; odds ratio .1; p = .008) and non-sedation coping actions (13% vs 28%; 7/55 vs 25/89; odds ratio .3; p = .02). Self-hypnosis did not influence the CLQ results measured before and after MR imaging (p = .79). Self-hypnosis reduced the frequency of claustrophobia in the subgroup of patients above an established CLQ cut-off of .33 from 47% (37/78) to 18% (9/49; p = .002). In the subgroup below the CLQ cut-off of 0.33, there were no significant differences (0% vs 9%, 0/6 vs 1/11; p = 1.0). Most patients (67%; 35/52) preferred self-hypnosis for future MR examinations. Conclusions Self-hypnosis reduced claustrophobia in high-risk patients undergoing imaging in an open MR scanner and might reduce the need for sedation and non-sedation coping actions. Key Points • Forty percent of the patients at high risk for claustrophobia may also experience a claustrophobic event in an open MR scanner. • Self-hypnosis while listening to an audio in the waiting room before the examination may reduce claustrophobic events in over 50% of patients with high risk for claustrophobia. • Self-hypnosis may also reduce the need for sedation and other time-consuming non-sedation coping actions and is preferred by high-risk patients for future examinations.

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Dysprosium-enhanced MR imaging for tumor tissue characterization

Acta Radiologica ◽

10.1080/02841859709172064 ◽

1997 ◽

Vol 38 (2) ◽

pp. 281-286 ◽

Cited By ~ 1

Author(s):

C. Wang ◽

A. Sundin ◽

A. Ericsson ◽

T. Bach-Gansmo ◽

A. Hemmingsson ◽

...

Keyword(s):

Mr Imaging ◽

Tissue Characterization ◽

Tumor Tissue ◽

Tumor Model ◽

Human Colon ◽

Mr Images ◽

Histological Sections ◽

Necrotic Tumor ◽

Before And After ◽

Weighted Sequences

Purpose: to evaluate dysprosium-enhanced MR imaging for differentiation between morphologically intact and necrotic tumor tissue in a tumor model. Material and Methods: A human colon carcinoma was transplanted subcutaneously into 9 nude (immunodeprived) rats. MR imaging was performed before and after injection of the dysprosium agent Dy-DTPA-BMA. T1-, T2- and T2*-weighted sequences were acquired. the tumors were dissected, histological sections were prepared, and compared with corresponding MR images. Results: in intact tissue, the MR signal intensity in the T2- and T2*-weighted images decreased after Dy injection and the delineation of the intact regions were sharp and corresponded well to the gross histological sections. Conclusion: Dy-enhanced MR imaging facilitated the differentiation between intact and necrotic tumor tissue.

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