Characterisation of captopril photolysis and photocatalysis by-products in water by direct infusion, electrospray ionisation, high-resolution mass spectrometry and the assessment of their toxicities

2017 ◽  
Vol 97 (1) ◽  
pp. 42-55 ◽  
Author(s):  
Julia Raquel Lino e Freitas ◽  
Frederico Jehár Oliveira Quintão ◽  
Júlio César Cardoso da Silva ◽  
Silvana de Queiroz Silva ◽  
Sérgio Francisco Aquino ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Direct Infusion ◽  
Electrospray Ionisation ◽  
High Resolution Mass ◽  
By Products ◽  
Resolution Mass

scholarly journals Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry

Chemosphere ◽  
2016 ◽  
Vol 154 ◽  
pp. 231-239 ◽  
Author(s):  
Jaime Nácher-Mestre ◽  
María Ibáñez ◽  
Roque Serrano ◽  
Clara Boix ◽  
Lubertus Bijlsma ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
By Products ◽  
Resolution Mass

Characterization of Disinfection By-Products from Chromatographically Isolated NOM through High-Resolution Mass Spectrometry

2015 ◽  
Vol 49 (24) ◽  
pp. 14239-14248 ◽  
Author(s):  
Bradley D. Harris ◽  
Taylor A. Brown ◽  
Jimmie L. McGehee ◽  
Dominika Houserova ◽  
Benjamin A. Jackson ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
By Products ◽  
Resolution Mass

Photodegradation of bisphenol A in aqueous medium: Monitoring and identification of by-products by liquid chromatography coupled to high-resolution mass spectrometry

2014 ◽  
Vol 28 (9) ◽  
pp. 987-994 ◽  
Author(s):  
Júlio César Cardoso da Silva ◽  
Janaina Aparecida Reis Teodoro ◽  
Robson José de Cássia Franco Afonso ◽  
Sérgio F. Aquino ◽  
Rodinei Augusti
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
High Resolution ◽  
Bisphenol A ◽  
Aqueous Medium ◽  
High Resolution Mass Spectrometry ◽  
High Resolution Mass ◽  
By Products ◽  
Resolution Mass

Study of the Fragmentation Pathways of Sulfonamides by High-resolution Mass Spectrometry: Application to their Detection in Plasma by Direct Infusion

2020 ◽  
Vol 16 (5) ◽  
pp. 513-519
Author(s):  
Maroula G. Kokotou
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Structural Features ◽  
Direct Infusion ◽  
Sulfonamide Antibiotics ◽  
Fragmentation Pathways ◽  
Fragment Ions ◽  
High Resolution Mass ◽  
Resolution Mass

Background: The high resolving and accuracy power of the HRMS instrument enabled us to identify the product ions and to propose detailed fragmentation pathways and diagnostic fragment ions. Methods: In the present work, the fragmentation pathways of five sulfonamides antibiotics, namely sulfamerazine, sulfathiazole, sulfadiazine, sulfadimethoxine and sulfamethoxazole, by High-Resolution Mass Spectrometry (HRMS) are presented. The HRMS spectra were recorded with a Q-TOF (Time of Flight) spectrometer with Electrospray Ionization (ESI) in both negative and positive mode. Results: Specific characteristic ions for each one of the sulfonamide antibiotics under positive ESI mode are proposed for the first time. Fragment ions of this particular class of analytes may be used to rapidly identify compounds with common structural features. Conclusion: The direct infusion of plasma samples, avoiding any prior chromatographic steps, to identify the existence of sulfonamide antibiotics is demonstrated herein.

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