Abstract
In modern agriculture, controlled-release formulations (CRF) is greatly desirable for achieving valid utilization and loss reduction of pesticides. It can also alleviate the adverse effect on non-target organism. In this study, we used polydopamine (PDA) as a depositing layer, constructed pyraclostrobin@SiO 2 @polydopamine microcapsule (Pyr@SiO 2 @PDA MC). The resulting microcapsule is a near-rod shape (about 1.152μm), which has a drug-loading efficiency of 55%. FT-IR and TG analysis revealed the successful entrapment of the pesticide. The microencapsulation had important function in the slow-release rate of the pyraclostrobin and superior UV-shielding properties. Moreover, bioactivity of the microcapsule against Fusarium oxysporum f.sp.vasinfectum was determined and it exhibited better inhibition activity than pyraclostrobin technical in the later stage. At last, acute toxicity tests demonstrated that Pyr@SiO 2 @PDA MC on zebrafish with lower toxicity on the first day. These results showed that Pyr@SiO 2 @PDA MC may process broader application potential in agriculture.In modern agriculture, controlled-release formulations (CRF) is greatly desirable for achieving valid utilization and loss reduction of pesticides. It can also alleviate the adverse effect on non-target organism. In this study, we used polydopamine (PDA) as a depositing layer, constructed pyraclostrobin@SiO 2 @polydopamine microcapsule (Pyr@SiO 2 @PDA MC). The resulting microcapsule is a near-rod shape (about 1.152μm), which has a drug-loading efficiency of 55%. FT-IR and TG analysis revealed the successful entrapment of the pesticide. The microencapsulation had important function in the slow-release rate of the pyraclostrobin and superior UV-shielding properties. Moreover, bioactivity of the microcapsule against Fusarium oxysporum f.sp.vasinfectum was determined and it exhibited better inhibition activity than pyraclostrobin technical in the later stage. At last, acute toxicity tests demonstrated that Pyr@SiO 2 @PDA MC on zebrafish with lower toxicity on the first day. These results showed that Pyr@SiO 2 @PDA MC may process broader application potential in agriculture.
Fabrication a controlled-release pesticide for improving UV-shielding properties and reducing toxicity via coating polydopamine
