Ganglioside GM3Derivatives with Truncated Ceramide Moiety: Facial Synthesis and Inhibitory Activity against KB Cell Growth

2006 ◽  
Vol 25 (5) ◽  
pp. 427-439 ◽  
Author(s):  
Michio Kurosu ◽  
Isao Kitagawa
Keyword(s):  
Cell Growth ◽  
Inhibitory Activity ◽  
Ceramide Moiety

scholarly journals Pro‑apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro

2020 ◽  
Vol 20 (5) ◽  
pp. 1-1
Author(s):  
Ilaria Lampronti ◽  
Daniele Simoni ◽  
Riccardo Rondanin ◽  
Riccardo Baruchello ◽  
Chiara Scapoli ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Inhibitory Activity ◽  
Tumor Cell Growth ◽  
Apoptotic Activity ◽  
Isoxazole Derivatives

Obtusifoliol related steroids from Euphorbia sogdiana with cell growth inhibitory activity and apoptotic effects on breast cancer cells (MCF-7 and MDA-MB231)

Steroids ◽  
2016 ◽  
Vol 115 ◽  
pp. 90-97 ◽  
Author(s):  
Mahmoud Aghaei ◽  
Zeinab Yazdiniapour ◽  
Mustafa Ghanadian ◽  
Behzad Zolfaghari ◽  
Virginia Lanzotti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Cancer Cells ◽  
Inhibitory Activity ◽  
Breast Cancer Cells ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Apoptotic Effects ◽  
Mcf 7

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity

2010 ◽  
Vol 20 (17) ◽  
pp. 5353-5356 ◽  
Author(s):  
Françoise Borcard ◽  
Matthias Baud ◽  
Claudia Bello ◽  
Giovanna Dal Bello ◽  
Francesco Grossi ◽  
...  
Keyword(s):  
Cell Growth ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Cancer Cell Growth ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity

Identification of an endothelial cell growth-inhibitory activity produced by human monocytes

1990 ◽  
Vol 188 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Didier Vilette ◽  
Hendra Setiadi ◽  
Marie-Paule Wautier ◽  
Jacques Caen ◽  
Jean-Luc Wautier
Keyword(s):  
Endothelial Cell ◽  
Cell Growth ◽  
Inhibitory Activity ◽  
Human Monocytes ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Endothelial Cell Growth

scholarly journals Bioactivity-guided Study of Antiproliferative Activities of Salvia Extracts

2011 ◽  
Vol 6 (5) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Gábor Janicsák ◽  
István Zupkó ◽  
Milena T. Nikolova ◽  
Peter Forgo ◽  
Andrea Vasas ◽  
...  
Keyword(s):  
Cell Growth ◽  
Inhibitory Activity ◽  
Breast Adenocarcinoma ◽  
Root Extract ◽  
Chloroform Fraction ◽  
Skin Carcinoma ◽  
Mcf7 Cells ◽  
Antiproliferative Effects ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity

The cytotoxic activities of the n-hexane, chloroform and aqueous methanolic fractions prepared from the methanolic extract of the leaves of 23 Salvia taxa were studied for their cell growth-inhibitory activity against human cervix adenocarcinoma (HeLa), skin carcinoma (A431) and breast adenocarcinoma (MCF7) cells using the MTT assay. The n-hexane fractions of six Salvia taxa (S. hispanica, S. nemorosa, S. nemorosa l. albiflora, S. pratensis, S. recognita and S. ringens) and the chloroform fraction of S. officinalis l. albiflora produced over 50% growth inhibition of the skin carcinoma cell line. None of the tested extracts showed substantial (above 50%) antiproliferative effects against HeLa and MCF7 cells. S. ringens was the most powerful among the studied Salvia species with a 61.8% cell growth inhibitory activity on A431 cells. In the case of S. ringens, other plant parts were also tested for antiproliferative effect, and the highest activities were recorded for the root extract. This was subjected to bioactivity-guided fractionation, which yielded four abietane diterpenes (royleanone, horminone, 7- O-methyl-horminone and 7-acetyl-horminone), one triterpene (erythrodiol-3-acetate) and β-sitosterol. Horminone, 7-acetyl-horminone and erythrodiol-3-acetate displayed marked concentration-dependent antiproliferative effects, while royleanone and 7 -O-methyl-horminone produced weaker activities.

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