Biophysical and molecular docking insight into interaction mechanism and thermal stability of human serum albumin isoforms with a semi-synthetic water-soluble camptothecin analog irinotecan hydrochloride

2016 ◽  
Vol 34 (7) ◽  
pp. 1545-1560 ◽  
Author(s):  
Mohd. Ishtikhar ◽  
Mohsin Vahid Khan ◽  
Shawez Khan ◽  
Sumit Kumar Chaturvedi ◽  
Gamal Badr ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Molecular Docking ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Interaction Mechanism ◽  
Water Soluble ◽  
Irinotecan Hydrochloride ◽  
Thermal Stability Of ◽  
Insight Into

Biophysical insight into the interaction of levocabastine with human serum albumin: spectroscopy and molecular docking approach

2020 ◽  
pp. 1-10
Author(s):  
Fahad M. Almutairi ◽  
Mohammad Rehan Ajmal ◽  
Mohammad Khursheed Siddiqi ◽  
Nabeela Majid ◽  
Adel Ibrahim Ahmad Al-Alawy ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Docking Approach ◽  
Insight Into

scholarly journals Gold nanoparticles increases UV and thermal stability of human serum albumin

2016 ◽  
Vol 11 (4) ◽  
pp. 04B310 ◽  
Author(s):  
Robin Capomaccio ◽  
Inês Osório ◽  
Isaac Ojea-Jiménez ◽  
Giacomo Ceccone ◽  
Pascal Colpo ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Gold Nanoparticles ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermal Stability Of

Biophysical and molecular docking insight into the interaction of cytosine β-D arabinofuranoside with human serum albumin

2015 ◽  
Vol 164 ◽  
pp. 123-130 ◽  
Author(s):  
Parvez Alam ◽  
Sumit Kumar Chaturvedi ◽  
Tamanna Anwar ◽  
Mohammad Khursheed Siddiqi ◽  
Mohd Rehan Ajmal ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Insight Into

Biophysical investigation of thymoquinone binding to ‘N’ and ‘B’ isoforms of human serum albumin: exploring the interaction mechanism and radical scavenging activity

RSC Advances ◽  
2015 ◽  
Vol 5 (24) ◽  
pp. 18218-18232 ◽  
Author(s):  
Mohd Ishtikhar ◽  
Gulam Rabbani ◽  
Shawez Khan ◽  
Rizwan Hasan Khan
Keyword(s):  
Thermal Stability ◽  
Antioxidant Activity ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Interaction Mechanism ◽  
Scavenging Activity

Thymoquinone more strongly interacts with the ‘N’ isoform in comparison to the ‘B’ isoform of HSA and also increases its thermal stability but the antioxidant activity is significantly higher at the ‘B’ isoform of HSA.

scholarly journals Investigation of the Interaction Mechanism between Salbutamol and Human Serum Albumin by Multispectroscopic and Molecular Docking

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Ting Zhao ◽  
Zihui Liu ◽  
Jingmei Niu ◽  
Baoxing Lv ◽  
Yuliang Xiao ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescence Spectra ◽  
Interaction Mechanism ◽  
Adrenergic Agonist ◽  
Airway Diseases ◽  
Synchronous Fluorescence Spectra ◽  
Multispectral Method

Salbutamol (SBAL), a kind of short-acting beta 2-adrenergic agonist, has been mainly used to treat bronchial asthma and other allergic airway diseases clinically. In this study, the interaction mechanism between salbutamol and human serum albumin was researched by the multispectral method and molecular docking. The fluorescence intensity of HSA could be regularly enhanced with the increase of SBAL concentration. Both the results of the multispectral method and molecular docking showed that SBAL could bind HSA with van der Waals force and hydrogen bonds. The binding mechanism was further analysed by UV-Vis and synchronous fluorescence spectra. The contents of the secondary structure of free HSA and SBAL-HSA complex were evaluated using CD spectra.

Effect of ketoprofen-based ionic liquids on secondary structure and thermal stability of human serum albumin

2020 ◽  
Vol 142 (5) ◽  
pp. 1911-1917
Author(s):  
Proletina Kardaleva ◽  
Maya Guncheva ◽  
Svetla Todinova ◽  
Ivan Angelov ◽  
Paula Ossowicz ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Ionic Liquids ◽  
Secondary Structure ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Thermal Stability Of
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