Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1

The T2 relaxation times recorded by nuclear magnetic resonance (NMR) logging are measures of the ratio of the internal surface area to volume of the formation pore system. Although standard porosity logs are restricted to estimating the volume, the NMR log partitions the pore space as a spectrum of pore sizes. These logs have great potential to elucidate carbonate sequences, which can have single, double, or triple porosity systems and whose pores have a wide variety of sizes and shapes. Continuous coring and NMR logging was made of the Cambro-Ordovician Arbuckle saline aquifer in a proposed CO2 injection well in southern Kansas. The large data set gave a rare opportunity to compare the core textural descriptions to NMR T2 relaxation time signatures over an extensive interval. Geochemical logs provided useful elemental information to assess the potential role of paramagnetic components that affect surface relaxivity. Principal component analysis of the T2 relaxation time subdivided the spectrum into five distinctive pore-size classes. When the T2 distribution was allocated between grainstones, packstones, and mudstones, the interparticle porosity component of the spectrum takes a bimodal form that marks a distinction between grain-supported and mud-supported texture. This discrimination was also reflected by the computed gamma-ray log, which recorded contributions from potassium and thorium and therefore assessed clay content reflected by fast relaxation times. A megaporosity class was equated with T2 relaxation times summed from 1024 to 2048 ms bins, and the volumetric curve compared favorably with variation over a range of vug sizes observed in the core. The complementary link between grain textures and pore textures was fruitful in the development of geomodels that integrates geologic core observations with petrophysical log measurements.

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Special Issue: NMR-Based Metabolomics

Molecules ◽

10.3390/molecules26113283 ◽

2021 ◽

Vol 26 (11) ◽

pp. 3283

Author(s):

Miriam Pérez-Trujillo ◽

Toby J. Athersuch

Keyword(s):

Mass Spectrometry ◽

Nuclear Magnetic Resonance ◽

Nmr Spectroscopy ◽

Magnetic Resonance ◽

Dynamic Range ◽

Chemical Information ◽

Special Issue ◽

The Core ◽

Analytical Platforms ◽

Nuclear Magnetic

Nuclear magnetic resonance (NMR) spectroscopy remains one of the core analytical platforms for metabolomics, providing complementary chemical information to others, such as mass spectrometry, and offering particular advantages in some areas of research on account of its inherent robustness, reproducibility, and phenomenal dynamic range [...]

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Unraveling the Core–Shell Structure of Ligand-Capped Sn/SnOxNanoparticles by Surface-Enhanced Nuclear Magnetic Resonance, Mössbauer, and X-ray Absorption Spectroscopies

ACS Nano ◽

10.1021/nn406344n ◽

2014 ◽

Vol 8 (3) ◽

pp. 2639-2648 ◽

Cited By ~ 74

Author(s):

Loredana Protesescu ◽

Aaron J. Rossini ◽

Dominik Kriegner ◽

Maxence Valla ◽

Antoine de Kergommeaux ◽

...

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Shell Structure ◽

Core Shell ◽

X Ray ◽

The Core ◽

Surface Enhanced ◽

Core Shell Structure ◽

X Ray Absorption ◽

Nuclear Magnetic

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Organization of the core lipids of lipoproteins from normal and cholesterol-fed rabbits. A proton nuclear magnetic resonance study

Biochemistry ◽

10.1021/bi00268a025 ◽

1982 ◽

Vol 21 (25) ◽

pp. 6483-6488 ◽

Cited By ~ 19

Author(s):

Paulus A. Kroon ◽

Joel Seidenberg

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Nuclear Magnetic Resonance Study ◽

Proton Nuclear Magnetic Resonance ◽

Magnetic Resonance Study ◽

The Core ◽

Nuclear Magnetic

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The First Visualization of Acid Treatments on Carbonates With 3D Nuclear-Magnetic-Resonance Imaging

SPE Journal ◽

10.2118/168198-pa ◽

2015 ◽

Vol 20 (04) ◽

pp. 678-688 ◽

Cited By ~ 4

Author(s):

M.. Krebs ◽

B.. Lungwitz ◽

A.. Souza ◽

A.. Pépin ◽

S.. Montoya ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Nuclear Magnetic Resonance Imaging ◽

Resonance Imaging ◽

Core Flow ◽

Rock Samples ◽

The Core ◽

Core Samples ◽

Nuclear Magnetic

Summary Carbonate reservoirs often show great heterogeneity in their inner rock structure, and stimulation treatments are often necessary to maintain or establish fluid production. Therefore, core-flow tests are usually conducted to test and model stimulation treatments within a laboratory scale to predict their performance. The visualization of wormholes that were created within core-flow tests requires novel technologies for evaluation and pathway-prediction purposes. Unfortunately, past visualization techniques were always associated with the destruction of the core sample, creating a demand for nondestructive methods. Nuclear-magnetic-resonance imaging (NMRI) is such a method that fulfills the approach of being nondestructive. The technology is widely known by medical applications, and this study developed a procedure on how to use the NMRI technology to visualize wormholes with NMRI in 3D. The study was started by initially choosing and obtaining various core samples that have different contents of calcite and dolomite. These core samples were imaged with the NMRI and microfocus-computed-tomography (µCT) technology in their unchanged state, and basic petrophysical experiments were conducted for initial experiments. The μCT technology was used as a reference visualization technique, because it provides a very high resolution with a corresponding high level of detail. Afterward, core-flow tests were conducted on the core samples with various acid systems and wormholes generated. Finally, the core samples with wormholes were imaged again with the NMRI and μCT technology, whereby the NMRI acquisition technique was improved toward imaging of rock samples, and the results were compared with the μCT results. The NMRI results showed moderate imaging achievements for the unchanged rock samples and high-quality imaging achievements for the extracted wormholes.

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Reservoir properties of drill cutting by the nuclear magnetic resonance relaxometry and dielectric spectroscopy data

Earth sciences and subsoil use ◽

10.21285/2686-9993-2020-43-3-364-374 ◽

2020 ◽

Vol 43 (3) ◽

pp. 364-374

Author(s):

A. A. Mezin ◽

M. Y. Shumskayte ◽

V. N. Glinskikh ◽

N. A. Golikov ◽

E. S. Chernova

Keyword(s):

Nuclear Magnetic Resonance ◽

Particle Size ◽

Magnetic Resonance ◽

Dielectric Spectroscopy ◽

Pore Space ◽

Reservoir Properties ◽

Drill Cuttings ◽

The Core ◽

Nuclear Magnetic Resonance Relaxometry ◽

Nuclear Magnetic

The purpose of the study is to extend the use of nuclear magnetic resonance relaxometry and dielectric spectrometry methods. This is realized through a complex interpretation of the data by the above methods to timely provide additional petrophysical information about the drill cuttings pore space properties and structure. The relevance of the study is that the data on the drill cuttings obtained by the NMR method can be used as prior information in the logging data interpretation before a detailed petrophysical study of the core sample or in case of the core absence in the sampling interval. The objects of study are the drill cuttings samples from the fields of the West Siberian oil-and-gas province. The samples are saturated with different fluids, and their reservoir properties are determined by the nuclear magnetic resonance and dielectric spectrometry methods. As part of the experimental research, nuclear magnetic resonance investigations of the core samples of different discretization degrees have been carried out to determine the reservoir properties of the samples depending on the degree of their particle size reduction. It has been shown that the obtained results do not depend on the particle size of the measured sample and are consistent with the results of the standard petrophysical studies. The relationship between the porosity and the saturating fluid type has been established. Based on the data obtained by the dielectric spectroscopy method, the study has determined the value of the complex dielectric constant that shows how the degree of saturation changes depending on the fluid, and what happens in the pore space. The complex interpretation of the results obtained by the two methods provides additional information on the drill cuttings reservoir properties that can be used as a priori information on the formation properties.

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Nuclear Magnetic Resonance Measurement of Oil and Water Distributions in Spontaneous Imbibition Process in Tight Oil Reservoirs

Energies ◽

10.3390/en11113114 ◽

2018 ◽

Vol 11 (11) ◽

pp. 3114 ◽

Cited By ~ 2

Author(s):

Xiangrong Nie ◽

Junbin Chen

Keyword(s):

Magnetic Resonance Imaging ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Spontaneous Imbibition ◽

Oil Reservoirs ◽

Tight Oil ◽

Resonance Imaging ◽

The Core ◽

Tight Oil Reservoirs ◽

Nuclear Magnetic

Spontaneous imbibition of water into tight oil reservoirs is considered an effective way to improve tight oil recovery. We have combined testing techniques such as nuclear magnetic resonance, mercury injection capillary pressure, and magnetic resonance imaging to reveal the distribution characteristics of oil and water during the spontaneous imbibition process of tight sandstone reservoir. The experimental results were used to describe the dynamic process of oil–water distribution at the microscopic scale. The water phase is absorbed into the core sample by micropores and mesopores under capillary forces that dry away the original oil phase into the hydraulically connected macropores. The oil phase entering the macropores will drive away the oil in place and expel the original oil from the macropores. The results of magnetic resonance imaging clearly show that the remaining oil accumulates in the central region of the core because a large amount of water is absorbed in the late stage of spontaneous imbibition, and the water in the pores gradually connects to form a “water shield” that blocks the flow of the oil phase. We propose the spontaneous imbibition pathway, which can effectively explain the internal mechanisms controlling the spontaneous imbibition rate. The surface of the core tends to form many spontaneous imbibition pathways, so the rate of spontaneous imbibition is fast. The deep core does not easily form many spontaneous imbibition pathways, so the rate of spontaneous imbibition is slow. This paper reveals the pore characteristics and distribution of oil and water during the spontaneous imbibition process, which is of significance for the efficient development of tight oil.

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Nuclear magnetic resonance affects the circadian clock and hypoxia-inducible factor isoforms in zebrafish

Biological Rhythm Research ◽

10.1080/09291016.2018.1498194 ◽

2018 ◽

Vol 50 (5) ◽

pp. 739-757 ◽

Cited By ~ 1

Author(s):

Regina Oliva ◽

Bianca Jansen ◽

Felix Benscheidt ◽

Adolf Michael Sandbichler ◽

Margit Egg

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Circadian Clock ◽

Hypoxia Inducible Factor ◽

Nuclear Magnetic

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An emerging technology: Nuclear magnetic resonance microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010010706x ◽

1988 ◽

Vol 46 ◽

pp. 1000-1001

Author(s):

M.J. Hennessy ◽

E. Kwok

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Relaxation Times ◽

Basic Research ◽

Local Environment ◽

Magnetic Resonance Images ◽

Nmr Microscopy ◽

Mri Scans ◽

Temperature Relaxation ◽

Nuclear Magnetic

Much progress in nuclear magnetic resonance microscope has been made in the last few years as a result of improved instrumentation and techniques being made available through basic research in magnetic resonance imaging (MRI) technologies for medicine. Nuclear magnetic resonance (NMR) was first observed in the hydrogen nucleus in water by Bloch, Purcell and Pound over 40 years ago. Today, in medicine, virtually all commercial MRI scans are made of water bound in tissue. This is also true for NMR microscopy, which has focussed mainly on biological applications. The reason water is the favored molecule for NMR is because water is,the most abundant molecule in biology. It is also the most NMR sensitive having the largest nuclear magnetic moment and having reasonable room temperature relaxation times (from 10 ms to 3 sec). The contrast seen in magnetic resonance images is due mostly to distribution of water relaxation times in sample which are extremely sensitive to the local environment.

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Nuclear magnetic resonance microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100156110 ◽

1989 ◽

Vol 47 ◽

pp. 828-829

Author(s):

Paul C. Lauterbur

Keyword(s):

Magnetic Field ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnetic Fields ◽

Signal To Noise ◽

Field Gradients ◽

Useful Signal ◽

Magnetic Field Gradients ◽

Observation Times ◽

Nuclear Magnetic

Nuclear magnetic resonance imaging can reach microscopic resolution, as was noted many years ago, but the first serious attempt to explore the limits of the possibilities was made by Hedges. Resolution is ultimately limited under most circumstances by the signal-to-noise ratio, which is greater for small radio receiver coils, high magnetic fields and long observation times. The strongest signals in biological applications are obtained from water protons; for the usual magnetic fields used in NMR experiments (2-14 tesla), receiver coils of one to several millimeters in diameter, and observation times of a number of minutes, the volume resolution will be limited to a few hundred or thousand cubic micrometers. The proportions of voxels may be freely chosen within wide limits by varying the details of the imaging procedure. For isotropic resolution, therefore, objects of the order of (10μm) may be distinguished.Because the spatial coordinates are encoded by magnetic field gradients, the NMR resonance frequency differences, which determine the potential spatial resolution, may be made very large. As noted above, however, the corresponding volumes may become too small to give useful signal-to-noise ratios. In the presence of magnetic field gradients there will also be a loss of signal strength and resolution because molecular diffusion causes the coherence of the NMR signal to decay more rapidly than it otherwise would. This phenomenon is especially important in microscopic imaging.

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