Association between Circulating Adiponectin and Heart Rate Recovery in Women with Polycystic Ovarian Syndrome

Abstract Background: Imbalance of autonomic nervous system is confirmed as a key contributor for cardiometabolic complications in polycystic ovarian syndrome (PCOS) women. Heart rate recovery (HRR) is an easy test for autonomic nervous tone evaluation and a powerful index for predicting cardiovascular events and mortality. Adiponectin (APN) is reported to be correlated closely with autonomic nervous function in different populations.Methods: This study aimed to investigate the relationship between serum total APN and HRR in PCOS women. A total of 89 PCOS women were enrolled and divided into two groups. Women with HRR values slower than 12 beats were defined as Blunted HRR Group. APN levels were compared between Blunted HRR Group and Normal HRR Group. Multivariate logistic regression analysis and multiple linear regression analysis were performed to determine which clinical variables were independently associated with decreased HRR and the effect of clinical variables on APNlevels, respectively. Results: 23 women were categorized in Blunted HRR Group, in which the APN level was significantly lower than Normal HRR Group (10.2±3.9 ug/ml vs. 13.1±4.1 ug/ml, P=0.015). Age [odds ratio (OR) = 1.15; 95% confidence interval (CI) = 1.04-1.21; P = 0.032], BMI (OR = 0.93; 95% CI = 0.72-1.08; P = 0.006), hypertension (OR = 1.08; 95%CI = 1.02-1.26; P = 0.025) and APN (OR= 0.61; 95%CI = 0.43-0.88; P = 0.018) were independent factors of attenuated HRR in PCOS women. Meanwhile, multiple linear regression analysis showed only age (β=-0.26; 95%CI =-0.47- -0.03, P= 0.041) and hyperlipemia (β=-0.13; 95%CI =-0.27-0.08, P= 0.024) were closely associated with APN levels in PCOS women.Conclusions: Our findings suggested that decreased APN concentration was closely associated with HRR blunt in PCOS women. Further studies are needed to explore the underlying interactions between APN and autonomic nervous function.

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Effect of Exercise and Weight Loss in Polycystic Ovarian Syndrome among Obese Women

Pertanika Journal of Science and Technology ◽

10.47836/pjssh.29.s1.07 ◽

2021 ◽

Vol 29 (S1) ◽

Author(s):

Thomas Cochrane ◽

Tengku Fadilah Tengku-Kamalden ◽

Rachel Davey ◽

Roxana Dev Omar Dev

Keyword(s):

Heart Rate ◽

Weight Loss ◽

Body Weight ◽

Polycystic Ovarian Syndrome ◽

Intervention Group ◽

Small Sample ◽

Lean Body Weight ◽

Obese Women ◽

Fat Percentage ◽

Ovarian Syndrome

Ovulation and fertility can be improved by weight loss in obese women with Polycystic Ovarian Syndrome (PCOS). The aim of this study was to investigate the effectiveness of a twelve-week supervised exercise program in combination with dietary restrictions for obese women with PCOS. The study is a quasi-experimental research and used an experimental pre- and post-test design. Fifteen women recruited from Fertility Clinic, Jessops Hospital for Women, Sheffield took part in this study. Respiratory exchange ratio (RER), heart rate, perceived exertion (RPE), and Houston non-exercise activity code were recorded. Height, weight, and body girth measurements were taken to calculate body mass index, fat percentage, and lean body weight. The intervention group lost an average of 3.1 kg and gained 3.45 kg of lean body weight. Loss of fat percentage was 12.1%. No significant difference was found in the control group. The RER and heart rate value decreased for the same workload in the intervention group, indicating higher tolerance towards exercise intensity. However, the changes for both groups were not significant. The average group compliance rate was 53% (at least two sessions per week). Bearing in mind the small sample size (n=4) for control, the improvement in fitness, significant weight loss, and body composition change (increase in fat-free mass) was achieved in this study. Twelve weeks of exercise, combined with dietary advice, were sufficient to benefit PCOS obese women. The research has achieved a commendable weight-loss objective and has demonstrated increases in standards of fitness among obese women.

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Abstract #782247: Polycystic Ovarian Syndrome: Variation in Diagnosis and Management

Endocrine Practice ◽

10.1016/s1530-891x(20)39422-2 ◽

2020 ◽

Vol 26 ◽

pp. 178

Author(s):

S.M. Ashrafuzzaman

Keyword(s):

Polycystic Ovarian Syndrome ◽

Diagnosis And Management ◽

Ovarian Syndrome

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Abstract #515: Effects of Bariatric Surgery on Metabolic Syndrome in Obese Women with Polycystic Ovarian Syndrome

Endocrine Practice ◽

10.1016/s1530-891x(20)45073-6 ◽

2016 ◽

Vol 22 ◽

pp. 124

Author(s):

Mc Anto Antony ◽

Shannon Sullivan

Keyword(s):

Bariatric Surgery ◽

Metabolic Syndrome ◽

Polycystic Ovarian Syndrome ◽

Obese Women ◽

Ovarian Syndrome

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ULTRASONOGRAPHIC FOLLOW-UP OF ANTIANDROGENIC THERAPY IN POLYCYSTIC OVARIAN SYNDROME

Ultraschall in der Medizin - European Journal of Ultrasound ◽

10.1055/s-2005-917591 ◽

2005 ◽

Vol 26 (S 1) ◽

Author(s):

D Pelinescu-Onciul ◽

R Radulescu-Botica

Keyword(s):

Polycystic Ovarian Syndrome ◽

Ovarian Syndrome ◽

Antiandrogenic Therapy

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Characteristics of Polycystic Ovarian Syndrome in Sub-fertile Woman Attending to GOPD in ShSMCH

Journal of Shaheed Suhrawardy Medical College ◽

10.3329/jssmc.v11i1.43173 ◽

2019 ◽

Vol 11 (1) ◽

pp. 17-23

Author(s):

Jinnat Ara Islam ◽

Fatema Ashraf ◽

Eva Rani Nandi

Keyword(s):

Polycystic Ovarian Syndrome ◽

Polycystic Ovaries ◽

Cross Sectional ◽

Medical College ◽

Appropriate Treatment ◽

Pcos Group ◽

Symptom Complex ◽

Ovarian Syndrome ◽

Selection Of ◽

Fertile Women

Background: Polycystic ovarian syndrome (PCOS) is a condition characterized by menstrual abnormalities (oligo/amenorrhea) and clinical or biochemical features of hyperandrogenism and may manifest at any age. It is a common cause of female subfertility. All the dimensions of PCOS have not been yet completely explored. Methods: It was a cross sectional comparative study carried out at-GOPD of Shaheed Suhrawardy Medical College & Hospital from January, 2016 to December 2016 on 162 subfertile women. Among them 54 were PCOS group and 108 were non PCOS group. PCOS was diagnosed by (Rotterdam criteria 2003) (i) Oligo or anovulation (ii) hyperandrogenism (iii) Polycystic ovaries. Study was done to evaluate and compare the demographic characteristics, clinical, biochemical and ultrasoundgraphic features of sub-fertile women with and without PCOS. Results: A total of 162 sub-fertile women aged 16-36 years. Mean age was 29.5±5.4. There were significant differences between the two groups in terms of (oligo/amenorrhea), hirsutism, WHR and ovarian ultrasound features. There were no significant differences between two groups in correlations between the level of obesity with the incidence of anovulation, hyperandrogenism or with hormonal features. Conclusion: PCOS is one of the important factors causing Infertility. It is an ill-defined symptom complex needed due attention. There is a need to increase awareness regarding. The clinical features of PCOS are heterogenous thus can be investigated accordingly of selection of appropriate treatment modality. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 17-23

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Heart Rate Recovery Changes during Competition Period in High-Level Basketball Players

Baltic Journal of Sport and Health Sciences ◽

10.33607/bjshs.v1i80.334 ◽

2018 ◽

Vol 1 (80) ◽

Author(s):

Audrius Gocentas ◽

Anatoli Landõr ◽

Aleksandras Kriščiūnas

Keyword(s):

Heart Rate ◽

Heart Rate Recovery ◽

Team Sports ◽

Basketball Players ◽

Coeffi Cients ◽

Competition Period ◽

Monitoring Training ◽

Intense Training ◽

High Level

Research background and hypothesis. Replete schedule of competitions and intense training are features of contemporary team sports. Athletes, especially the most involved ones, may not have enough time to recover. As a consequence, aggregated fatigue can manifest in some undesirable form and affect athlete’s performance and health.Research aim. The aim of this study was to evaluate the changes in heart rate recovery (HRR) and investigate possible relations with sport-speciﬁ c measures of efﬁ cacy in professional basketball players during competition season.Research methods. Eight male high-level basketball players (mean ± SD, body mass, 97.3 ± 11.33 kg; height 2.02 ± 0.067 m, and age 23 ± 3.12 years) were investigated. The same basketball speciﬁ c exercise was replicated several times from September till April during the practice sessions in order to assess the personal trends of HRR. Heart rate monitoring was performed using POLAR TEAM SYSTEM. Investigated athletes were ranked retrospectively according to the total amount of minutes played and the coefﬁ cients of efﬁ cacy. Research results. There were signiﬁ cant differences in the trends of HRR between the investigated players. The most effective players showed decreasing trends of HRR in all cases of ranking.Discussion and conclusions. Research ﬁ ndings have shown that the quality of heart rate recovery differs between basketball players of the same team and could be associated with sport-speciﬁ c efﬁ cacy and competition playing time.Keywords: adaptation, autonomic control, monitoring training.

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