Apparent reflectance modeling for camouflage pattern comparison metrics

Author(s):  
Edward Michaelchuck Jr. ◽  
Scott Ramsey ◽  
Troy Mayo ◽  
Sarah Thompson ◽  
Samuel Lambrakos
Blood ◽  
2010 ◽  
Vol 116 (15) ◽  
pp. e66-e73 ◽  
Author(s):  
Chih-Wen Ni ◽  
Haiwei Qiu ◽  
Amir Rezvan ◽  
Kihwan Kwon ◽  
Douglas Nam ◽  
...  

Abstract Recently, we showed that disturbed flow caused by a partial ligation of mouse carotid artery rapidly induces atherosclerosis. Here, we identified mechanosensitive genes in vivo through a genome-wide microarray study using mouse endothelial RNAs isolated from the flow-disturbed left and the undisturbed right common carotid artery. We found 62 and 523 genes that changed significantly by 12 hours and 48 hours after ligation, respectively. The results were validated by quantitative polymerase chain reaction for 44 of 46 tested genes. This array study discovered numerous novel mechanosensitive genes, including Lmo4, klk10, and dhh, while confirming well-known ones, such as Klf2, eNOS, and BMP4. Four genes were further validated for protein, including LMO4, which showed higher expression in mouse aortic arch and in human coronary endothelium in an asymmetric pattern. Comparison of in vivo, ex vivo, and in vitro endothelial gene expression profiles indicates that numerous in vivo mechanosensitive genes appear to be lost or dysregulated during culture. Gene ontology analyses show that disturbed flow regulates genes involved in cell proliferation and morphology by 12 hours, followed by inflammatory and immune responses by 48 hours. Determining the functional importance of these novel mechanosensitive genes may provide important insights into understanding vascular biology and atherosclerosis.


Author(s):  
Cynthia Jongen ◽  
Josien P. W. Pluim ◽  
Max A. Viergever ◽  
Wiro J. Niessen

2020 ◽  
Author(s):  
Banu Ahtam ◽  
Ted K Turesky ◽  
Lilla Zöllei ◽  
Julianna Standish ◽  
P Ellen Grant ◽  
...  

Abstract Intergenerational effects are described as the genetic, epigenetic, as well as pre- and postnatal environmental influence parents have on their offspring’s behavior, cognition, and brain. During fetal brain development, the primary cortical sulci emerge with a distinctive folding pattern that are under strong genetic influence and show little change of this pattern throughout postnatal brain development. We examined intergenerational transmission of cortical sulcal patterns by comparing primary sulcal patterns between children (N = 16, age 5.5 ± 0.81 years, 8 males) and their biological mothers (N = 15, age 39.72 ± 4.68 years) as well as between children and unrelated adult females. Our graph-based sulcal pattern comparison method detected stronger sulcal pattern similarity for child–mother pairs than child-unrelated pairs, where higher similarity between child–mother pairs was observed mostly for the right lobar regions. Our results also show that child–mother versus child-unrelated pairs differ for daughters and sons with a trend toward significance, particularly for the left hemisphere lobar regions. This is the first study to reveal significant intergenerational transmission of cortical sulcal patterns, and our results have important implications for the study of the heritability of complex behaviors, brain-based disorders, the identification of biomarkers, and targets for interventions.


2014 ◽  
Vol 20 (6) ◽  
pp. 630-641 ◽  
Author(s):  
Noelle E. Carlozzi ◽  
David S. Tulsky ◽  
Nancy D. Chiaravalloti ◽  
Jennifer L. Beaumont ◽  
Sandra Weintraub ◽  
...  

AbstractThe NIH Toolbox (NIHTB) Pattern Comparison Processing Speed Test was developed to assess processing speed within the NIHTB for the Assessment of Neurological Behavior and Function Cognition Battery (NIHTB-CB). This study highlights validation data collected in adults ages 18–85 on this measure and reports descriptive data, test–retest reliability, construct validity, and preliminary work creating a composite index of processing speed. Results indicated good test–retest reliability. There was also evidence for both convergent and discriminant validity; the Pattern Comparison Processing Speed Test demonstrated moderate significant correlations with other processing speed tests (i.e., WAIS-IV Coding, Symbol Search and Processing Speed Index), small significant correlations with measures of working memory (i.e., WAIS-IV Letter-Number Sequencing and PASAT), and non-significant correlations with a test of vocabulary comprehension (i.e., PPVT-IV). Finally, analyses comparing and combining scores on the NIHTB Pattern Comparison Processing Speed Test with other measures of simple reaction time from the NIHTB-CB indicated that a Processing Speed Composite score performed better than any test examined in isolation. The NIHTB Pattern Comparison Processing Speed Test exhibits several strengths: it is appropriate for use across the lifespan (ages, 3–85 years), it is short and easy to administer, and it has high construct validity. (JINS, 2014,20, 1–12)


Cancer ◽  
2007 ◽  
Vol 109 (3) ◽  
pp. 518-527 ◽  
Author(s):  
Leslie S. Wilson ◽  
Ross Tesoro ◽  
Eric P. Elkin ◽  
Natalia Sadetsky ◽  
Jeanette M. Broering ◽  
...  

Pain Practice ◽  
2012 ◽  
Vol 12 (8) ◽  
pp. 641-648 ◽  
Author(s):  
Peter Sun ◽  
Yang Zhao ◽  
Zhenxiang Zhao ◽  
Mark Bernauer ◽  
Peter Watson

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