Ability to downregulate the level of cyclin-dependent kinase inhibitor p27Kip1 after DNA damage is retained in chronic lymphocytic leukemia cells with functional ATM/p53 signaling pathway

2016 ◽  
Vol 58 (1) ◽  
pp. 199-203 ◽  
Author(s):  
Leona Raskova Kafkova ◽  
Veronika Navrkalova ◽  
Marie Jarosova ◽  
Tomas Loja ◽  
Jana Chovancova ◽  
...  
Keyword(s):  
Dna Damage ◽  
Chronic Lymphocytic Leukemia ◽  
Signaling Pathway ◽  
Kinase Inhibitor ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Cyclin Dependent Kinase ◽  
Cyclin Dependent Kinase Inhibitor ◽  
P53 Signaling ◽  
P53 Signaling Pathway

scholarly journals Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells

Leukemia ◽  
2004 ◽  
Vol 18 (4) ◽  
pp. 747-755 ◽  
Author(s):  
I N Hahntow ◽  
F Schneller ◽  
M Oelsner ◽  
K Weick ◽  
I Ringshausen ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Kinase Inhibitor ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Cyclin Dependent Kinase ◽  
Cyclin Dependent Kinase Inhibitor

scholarly journals Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0143685 ◽  
Author(s):  
Cody Paiva ◽  
J. Claire Godbersen ◽  
Ryan S. Soderquist ◽  
Taylor Rowland ◽  
Sumner Kilmarx ◽  
...  
Keyword(s):  
B Cells ◽  
Chronic Lymphocytic Leukemia ◽  
P38 Mapk ◽  
Kinase Inhibitor ◽  
Lymphocytic Leukemia ◽  
Dependent Manner ◽  
Cyclin Dependent Kinase ◽  
Cyclin Dependent Kinase Inhibitor
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