An outbreak of severe coagulopathy from synthetic cannabinoids tainted with Long-Acting anticoagulant rodenticides

2019 ◽  
Vol 58 (8) ◽  
pp. 821-828 ◽  
Author(s):  
Jason M. Devgun ◽  
Arkady Rasin ◽  
Theresa Kim ◽  
Mark B. Mycyk ◽  
Sean M. Bryant ◽  
...  
Keyword(s):  
Synthetic Cannabinoids ◽  
Anticoagulant Rodenticides ◽  
Long Acting ◽  
Severe Coagulopathy

scholarly journals Bad weed: synthetic cannabinoid–associated coagulopathy

Blood ◽  
2019 ◽  
Vol 133 (9) ◽  
pp. 902-905 ◽  
Author(s):  
Gowthami M. Arepally ◽  
Thomas L. Ortel
Keyword(s):  
Public Health ◽  
Vitamin K ◽  
Synthetic Cannabinoids ◽  
Health Impact ◽  
Synthetic Cannabinoid ◽  
Public Health Impact ◽  
The Public ◽  
Recent Exposure ◽  
Anticoagulant Rodenticides ◽  
Long Acting

Abstract Recent multistate outbreaks of coagulopathy caused by brodifacoum-tainted synthetic cannabinoids or “fake weed” highlight the public health impact of long-acting anticoagulant rodenticides (LAARs). Patients presenting with this syndrome have had recent exposure to synthetic cannabinoids, evidence of isolated vitamin K antagonism with or without bleeding, and detectable levels of brodifacoum and other LAARs in circulation. This article will provide information on synthetic cannabinoids, LAARs, and coagulopathic manifestations arising from use of adulterated synthetic cannabinoids and their management.

scholarly journals Severe Vitamin K-dependent Coagulopathy from Rodenticide-contaminated Synthetic Cannabinoids: Emergency Department Presentations

2021 ◽  
Vol 22 (4) ◽  
pp. 1014-1019
Author(s):  
Erik Wright ◽  
John Hafner ◽  
Gregory Podolej ◽  
Douglas Feinstein ◽  
Richard van Breemen ◽  
...  
Keyword(s):  
United States ◽  
Emergency Department ◽  
Retrospective Cohort ◽  
Synthetic Cannabinoids ◽  
The United States ◽  
Designer Drugs ◽  
Treatment Results ◽  
Severe Vitamin ◽  
Long Acting ◽  
Serum Testing

Introduction: Synthetic cannabinoids are a rapidly expanding subset of designer drugs widely available in the United States since 2008. In Illinois during the spring of 2018, over 160 documented cases of bleeding and prolonged coagulopathy occurred secondary to contaminated synthetic cannabinoids. Methods: We conducted a retrospective cohort study consisting of 38 patients to describe the initial emergency department (ED) presentation, diagnosis, and treatment. Results: Through serum testing we found that three long-acting anticoagulant rodenticides (LAAR) were detected in patients who had inhaled these tainted products: brodifacoum, difenacoum, and bromodialone. Discussion: This study encompasses the largest ED presentation of LAAR poisoning via the inhalational route known to date. Conclusion: The emergency physician should be aware of the potential for tainted coingestants as the cause of undifferentiated coagulopathy.

scholarly journals Synthetic cannabinoid-associated coagulopathy secondary to long-acting anticoagulant rodenticides

Medicine ◽  
2019 ◽  
Vol 98 (36) ◽  
pp. e17015 ◽  
Author(s):  
Mona N. Bahouth ◽  
Peggy Kraus ◽  
Kathryn Dane ◽  
Manuela Plazas Montana ◽  
William Tsao ◽  
...  
Keyword(s):  
Synthetic Cannabinoid ◽  
Anticoagulant Rodenticides ◽  
Long Acting

scholarly journals Unmet clinical laboratory need in patients hospitalized for acute poisoning from long-acting anticoagulant rodenticides

2021 ◽  
Vol 5 (1) ◽  
pp. 93-96
Author(s):  
Richard B. van Breemen ◽  
John W. Hafner ◽  
Daniel G. Nosal ◽  
Douglas L. Feinstein ◽  
Israel Rubinstein
Keyword(s):  
Clinical Laboratory ◽  
Acute Poisoning ◽  
Anticoagulant Rodenticides ◽  
Long Acting

scholarly journals Pregnancy in Women With Life-Threatening Poisoning With Long-Acting Anticoagulant Rodenticides

2019 ◽  
Vol 94 (8) ◽  
pp. 1646-1647 ◽  
Author(s):  
Maidah Yaqoob ◽  
Douglas L. Feinstein ◽  
Israel Rubinstein
Keyword(s):  
Anticoagulant Rodenticides ◽  
Life Threatening ◽  
Long Acting

scholarly journals Deliberate self-poisoning with long-acting anticoagulant rodenticides

2017 ◽  
pp. bcr-2017-222170 ◽  
Author(s):  
Danielle Reimer ◽  
Melissa Smith ◽  
Sayed Ali
Keyword(s):  
Anticoagulant Rodenticides ◽  
Long Acting
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