scholarly journals The potential risk of combined effects of water and tillage erosion on the agricultural landscape in Czechia

2021 ◽  
pp. 1-11
Author(s):  
Daniel Žížala ◽  
Anna Juřicová ◽  
Jiří Kapička ◽  
Ivan Novotný
Keyword(s):  
Potential Risk ◽  
Agricultural Landscape ◽  
Combined Effects ◽  
Tillage Erosion

scholarly journals Effects of endplate coverage and intervertebral height change on heterotopic ossification following cervical disc replacement

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yi-Wei Shen ◽  
Yi Yang ◽  
Hao Liu ◽  
Xin Rong ◽  
Chen Ding ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heterotopic Ossification ◽  
Potential Risk ◽  
Disc Height ◽  
Cervical Disc ◽  
Combined Effects ◽  
Cervical Disc Replacement ◽  
Depth Ratio ◽  
Potential Risk Factors ◽  
Height Change

Abstract Background Heterotopic ossification (HO) is a common complication after cervical disc replacement (CDR). Biomechanical factors including endplate coverage and intervertebral disc height change may be related to HO formation. However, there is a dearth of quantitative analysis for endplate coverage, intervertebral height change and their combined effects on HO. Methods Patients who underwent single-level or two-level CDR with Prestige-LP were retrospectively reviewed. Clinical outcomes were evaluated through Japanese Orthopaedic Association (JOA) score, Neck Disability Index (NDI) score, and visual analogue scale (VAS) score. Radiological data, including the prosthesis-endplate depth ratio, intervertebral height change, posterior heterotopic ossification (PHO) and angular parameters, were collected. Logistic regression analysis was used to identify the potential risk factors. Receiver operating characteristic curves were plotted and the cut-off values of each potential factors were calculated. Results A total of 138 patients with 174 surgical segments were evaluated. Both the prosthesis-endplate depth ratio (P < 0.001) and post-operative disc height change (P < 0.001) were predictive factors for PHO formation. The area under the curve (AUC) of the prosthesis-endplate depth ratio, disc height change and their combined effects represented by the combined parameter (CP) were 0.728, 0.712 and 0.793, respectively. The risk of PHO significantly increased when the prosthesis-endplate depth ratio < 93.77% (P < 0.001, OR = 6.909, 95% CI 3.521–13.557), the intervertebral height change ≥ 1.8 mm (P < 0.001, OR = 5.303, 95% CI 2.592–10.849), or the CP representing the combined effect < 84.88 (P < 0.001, OR = 10.879, 95% CI 5.142–23.019). Conclusions Inadequate endplate coverage and excessive change of intervertebral height are both potential risk factors for the PHO after CDR. Endplate coverage less than 93.8% or intervertebral height change more than 1.8 mm would increase the risk of PHO. The combination of these two factors may exacerbate the non-uniform distribution of stress in the bone-implant interface and promote HO development.

scholarly journals Combined Toxicity of Chlorpyrifos, Abamectin, Imidacloprid, And Acetamiprid On Earthworms (Eisenia Fetida)

2021 ◽  
Author(s):  
Miaomiao Teng ◽  
Xiaoli Zhao ◽  
Chen Wang ◽  
Lingfeng Zhou ◽  
Xiaowei Wu ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Exposure Time ◽  
Environmental Risk ◽  
Potential Risk ◽  
Eisenia Fetida ◽  
Combined Effects ◽  
Additive Effects ◽  
Combined Toxicity ◽  
Median Lethal Concentrations ◽  
High Concentrations

Abstract Mixed pesticides have been broadly used in agriculture. However, assessing the combined effects of pesticides in the environment is essential for potential risk assessment, though the task is far from complete. Median lethal concentrations of pesticides as well as acetylcholinesterase (AChE) levels and cellulose activities were measured in earthworms (Eisenia fetida) individually and jointly exposed to pesticides imidacloprid (IMI), acetamiprid (ACE), chlorpyrifos (CRF), and abamectin (ABM)). A 3:1 mixture of CRF and IMI had additive effects, while a 3:1 mixture of CRF and ACE had synergic effects. The joint effects of ABM with IMI or with ACE were synergistic. As CRF concentration increased, AChE activities were significantly decreased. For high concentrations of IMI, AChE activities under combined CRF and IMI applications were significantly inhibited following increased exposure time. Moreover, the cellulase activities under combined applications of CRF with IMI or with ACE had similar effects. This study provides basic data for scientifically evaluating the environmental risk and safety of combined uses of pesticides.

Effects of Retinoic Acid and 1,25-Dihydroxyvitamin D3 on IFN-gamma Secretion by Mononuclear Leukocytes from Nulliparous and Postparturient Dairy Cattle

2000 ◽  
Vol 70 (3) ◽  
pp. 92-101 ◽  
Author(s):  
Burim Ametaj ◽  
Brian Nonnecke ◽  
Ronald Horst ◽  
Donald Beitz
Keyword(s):  
Retinoic Acid ◽  
Dairy Cattle ◽  
Dairy Cows ◽  
Dairy Cow ◽  
Pokeweed Mitogen ◽  
Mononuclear Leukocytes ◽  
Combined Effects ◽  
Ifn Gamma ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D

Individual and combined effects of several isomers of retinoic acid (RA) and 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) on interferon-gamma (IFN-gamma) secretion by blood mononuclear leukocytes (MNL) from nulliparous and postparturient Holstein cattle were evaluated in vitro. In the first experiment, effects on incubation period (24 to 72 hours) and time of supplementation (0 to 32 hours) with all-trans, 9-cis, 13-cis-, and 9,13-dicis-RAs (0 to 100 nM) on IFN-gamma secretion by pokeweed mitogen (PWM)-stimulated (0 and 10 mug/ml) MNL from nulliparous cattle were evaluated. In the second experiment, MNL from postparturient cows (bled at 0, 2, 4, and 16 days postpartum) were stimulated with PWM (0 and 10 mug/ml) in the presence of RA isomers (9-cis- or 9,13-dicis-RA; 0 to 100 nM), 1,25-(OH)2D3 (0 to 100 nM), or with combinations of these metabolites. The results show that individual isomers of RA had no effect on IFN-gamma secretion by PWM-stimulated MNL from nulliparous or postparturient cows. Furthermore 1,25-dihydroxyvitamin D3 inhibited IFN-gamma secretion by MNL from nulliparous and postparturient dairy cows; however, the degree of inhibition was greater when 9-cis- and 9,13-dicis-RA were also present in the cultures. Finally mononuclear leukocytes from postparturient dairy cows produced substantially less IFN-gamma than did MNL from nulliparous cattle. It is concluded that retinoic acids individually did not affect the capacity of leukocytes from dairy cattle to secrete IFN-gamma. This result is in marked contrast to studies in monogastric species indicating that RAs inhibit IFN-gamma secretion by peripheral blood T cells. Inhibition of IFN-gamma secretion by 1,25-(OH)2D3 was potentiated by 9-cis- and 9,13-di-cis-retinoics acids, suggesting that an excess of dietary vitamins A and D may compromise further the naturally immunosuppressed postparturient dairy cow. Additional research is necessary to determine if the combined effects of these metabolites on IFN-gamma secretion represent an increased susceptibility of the dairy cow to infectious diseases during the periparturient period. Lower secretion of IFN-gamma by MNL from postpartutient dairy cows, relative to nulliparous cattle, suggests that recently-calved cows are naturally immunosuppressed.

Pulmonary emboli due to venous aneurysm of extremities

VASA ◽  
2011 ◽  
Vol 40 (4) ◽  
pp. 327-332 ◽  
Author(s):  
Gabrielli ◽  
Rosati ◽  
Vitale ◽  
Millarelli ◽  
Siani ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Surgical Resection ◽  
Potential Risk ◽  
Acute Pulmonary Embolism ◽  
Prophylactic Surgery ◽  
Venous Aneurysm ◽  
Pulmonary Emboli ◽  
Thromboembolic Events ◽  
Thromboembolic Complications ◽  
Risk Patients

Venous aneurysms are uncommon but they can have devastating consequences, including pulmonary embolism, other thromboembolic events and death. We report six cases of venous aneurysm of the extremities, in which the first sign of presence was acute pulmonary embolism. Surgical resection is recommended whenever possible. Our experience suggests that prophylactic surgery is cautiously recommended for low-risk patients with venous aneurysms of the abdomen and strongly recommended for extremity deep and superficial venous aneurysms for their potential risk of developing thromboembolic complications despite adequate anticoagulation. Other venous aneurysms should be excised only if they are symptomatic or enlarging.

Transmyocardial Laser Revascularisation - A Potential Risk in Acute Situation?

Swiss Surgery ◽  
2000 ◽  
Vol 6 (2) ◽  
pp. 65-68
Author(s):  
Mueller ◽  
Tevaearai ◽  
Genton ◽  
Bettex ◽  
von Segesser
Keyword(s):  
Potential Risk ◽  
Transmyocardial Laser Revascularisation ◽  
Analyse Morphométrique

Les effets morphologiques et fonctionnels de la revascularisation transmyocardique au laser (RTML) sont analysés en conditions aiguës sur un modèle porcin. La paroi latérale du ventricule gauche de 15 porcs (poids moyen: 73 +/- 4kg) a été percée de 10 canaux laser (laser: Ho-YAG; longueur d'onde: 2.1 u, diamètre de la sonde: 1.75 mm). Une échocardiographie a été effectuée avant, ainsi que 5 min et 30 min après la procédure. Les paramètres échocardiographiques ont été enregistrés en court axe à la hauteur des canaux laser. Ils comprenaient la fraction d'éjection, la fraction de raccourcissement et la motilité segmentaire de la région lasérisée (échelle de 0 à 3: 0 = normal, 1 = hypokinésie, 2 = akinésie, 3 = dyskinésie). Après sacrifice de l'animal, la région lasérisée a été coupée dans un plan perpendiculaire aux canaux pour histologie et analyse morphométrique. Après 5 min, tous les index échocardiographiques ont montré une aggravation significative par rapport aux valeurs de base (p < 0.01). Après 30 min, plus aucun des paramètres ne présentait de variation significative par rapport aux valeurs de base. La surface de section des lésions mesurait 8.8 +/- 2.4 mm2 soit plus du triple de celle de la sonde laser elle-même (p < 0.01). En conditions aiguës, les lésions dues à la sonde de RTML sont nettement plus grande que la sonde elle-même et entraînent une baisse transitoire de la contractilité segmentaire sur un coeur sain. Ces résultats suggèrent que la RTML doit être utilisée avec prudence en clinique chez les patients avec une mauvaise fonction ventriculaire.

Combined effects of form- and meaning-based predictability on perceived clarity of speech.

2018 ◽  
Vol 44 (2) ◽  
pp. 277-285 ◽  
Author(s):  
Carine Signoret ◽  
Ingrid Johnsrude ◽  
Elisabet Classon ◽  
Mary Rudner
Keyword(s):  
Combined Effects

Combined effects of the prosteatotic TM6SF2 and PNPLA3 variants on severity of NALFD: multicentre biopsy-based study in German patients

2015 ◽  
Vol 53 (12) ◽  
Author(s):  
M Krawczyk ◽  
M Rau ◽  
J Schattenberg ◽  
H Bantel ◽  
A Pathil ◽  
...  
Keyword(s):  
Combined Effects

Premature Arterial Disease Associated with Familial Antithrombin III Deficiency

1990 ◽  
Vol 63 (01) ◽  
pp. 013-015 ◽  
Author(s):  
E J Johnson ◽  
C R M Prentice ◽  
L A Parapia
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Potential Risk ◽  
Antithrombin Iii ◽  
Arterial Disease ◽  
Coagulation System ◽  
Early Age ◽  
Arterial Thromboembolism ◽  
Potential Risk Factors ◽  
Antithrombin Iii Deficiency

SummaryAntithrombin III (ATIII) deficiency is one of the few known abnormalities of the coagulation system known to predispose to venous thromboembolism but its relation to arterial disease is not established. We describe two related patients with this disorder, both of whom suffered arterial thrombotic events, at an early age. Both patients had other potential risk factors, though these would normally be considered unlikely to lead to such catastrophic events at such an age. Thrombosis due to ATIII deficiency is potentially preventable, and this diagnosis should be sought more frequently in patients with arterial thromboembolism, particularly if occurring at a young age. In addition, in patients with known ATIII deficiency, other risk factors for arterial disease should be eliminated, if possible. In particular, these patients should be counselled against smoking.

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