mRNA-based dendritic cell immunization improves survival in ret transgenic mouse melanoma model

OncoImmunology ◽

10.1080/2162402x.2016.1160183 ◽

2016 ◽

Vol 5 (6) ◽

pp. e1160183 ◽

Author(s):

Adi Sharbi-Yunger ◽

Mareike Grees ◽

Esther Tzehoval ◽

Jochen Utikal ◽

Viktor Umansky ◽

...

Keyword(s):

Dendritic Cell ◽

Transgenic Mouse ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Dormant tumor cells interact with memory CD8+ T cells in RET transgenic mouse melanoma model

Cancer Letters ◽

10.1016/j.canlet.2020.01.016 ◽

2020 ◽

Vol 474 ◽

pp. 74-81 ◽

Author(s):

Fernando Flores-Guzmán ◽

Jochen Utikal ◽

Viktor Umansky

Keyword(s):

T Cells ◽

Tumor Cells ◽

Transgenic Mouse ◽

Cd8 T Cells ◽

Memory Cd8 T Cells ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Melanoma Model ◽

Download Full-text

Abstract 1593: Neutralization of IL-10 enhances antitumor efficacy of dendritic cell-targeting MIP-3α-gp100 vaccine by way of type-I interferons in B16F10 mouse melanoma model

10.1158/1538-7445.am2017-1593 ◽

2017 ◽

Author(s):

James Gordy ◽

Kun Luo ◽

Richard Markham

Keyword(s):

Dendritic Cell ◽

Type I Interferons ◽

Antitumor Efficacy ◽

Type I ◽

Cell Targeting ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Fusion of the dendritic cell-targeting chemokine MIP3α to melanoma antigen Gp100 in a therapeutic DNA vaccine significantly enhances immunogenicity and survival in a mouse melanoma model

Journal for ImmunoTherapy of Cancer ◽

10.1186/s40425-016-0189-y ◽

2016 ◽

Vol 4 (1) ◽

Author(s):

James T. Gordy ◽

Kun Luo ◽

Hong Zhang ◽

Arya Biragyn ◽

Richard B. Markham

Keyword(s):

Dendritic Cell ◽

Dna Vaccine ◽

Cell Targeting ◽

Melanoma Antigen ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Melanoma Model ◽

Therapeutic Dna Vaccine

Download Full-text

Abstract 2511: Therapeutic dendritic cell targeting MIP3α-gp100 DNA vaccination with immunomodulatory αIL-10 and αPD-1 antibodies significantly enhances survival in a mouse melanoma model system

10.1158/1538-7445.am2015-2511 ◽

2015 ◽

Author(s):

James Gordy ◽

Richard B. Markham

Keyword(s):

Dendritic Cell ◽

Dna Vaccination ◽

Model System ◽

Cell Targeting ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Abstract A13: Optimization of a dendritic cell-targeting MIP3α-antigen fusion vaccine in the B16F10 mouse melanoma model

10.1158/2326-6074.tumimm17-a13 ◽

2018 ◽

Author(s):

James T. Gordy ◽

Kun Luo ◽

Richard B. Markham

Keyword(s):

Dendritic Cell ◽

Cell Targeting ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Effect of artesunate on immune cells in ret-transgenic mouse melanoma model

Anti-Cancer Drugs ◽

10.1097/cad.0b013e328330caba ◽

2009 ◽

Vol 20 (10) ◽

pp. 910-917 ◽

Author(s):

Marcel Ramacher ◽

Viktor Umansky ◽

Thomas Efferth

Keyword(s):

Transgenic Mouse ◽

Immune Cells ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Anti-IL-10–mediated Enhancement of Antitumor Efficacy of a Dendritic Cell–targeting MIP3α-gp100 Vaccine in the B16F10 Mouse Melanoma Model Is Dependent on Type I Interferons

Journal of Immunotherapy ◽

10.1097/cji.0000000000000212 ◽

2018 ◽

Vol 41 (4) ◽

pp. 181-189 ◽

Author(s):

James T. Gordy ◽

Kun Luo ◽

Brian Francica ◽

Charles Drake ◽

Richard B. Markham

Keyword(s):

Dendritic Cell ◽

Type I Interferons ◽

Antitumor Efficacy ◽

Type I ◽

Cell Targeting ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1108121108 ◽

2011 ◽

Vol 108 (41) ◽

pp. 17111-17116 ◽

Author(s):

C. Meyer ◽

A. Sevko ◽

M. Ramacher ◽

A. V. Bazhin ◽

C. S. Falk ◽

...

Keyword(s):

Chronic Inflammation ◽

Transgenic Mouse ◽

Antitumor Immunity ◽

Cell Activation ◽

Suppressor Cell ◽

Mouse Melanoma ◽

Myeloid Derived Suppressor Cell ◽

Mouse Melanoma Model ◽

Download Full-text

Correction: Intratumoral injection reduces toxicity and antibody-mediated neutralization of immunocytokine in a mouse melanoma model

Journal for ImmunoTherapy of Cancer ◽

10.1136/jitc-2020-001262corr1 ◽

2020 ◽

Vol 8 (2) ◽

pp. e001262corr1

Keyword(s):

Intratumoral Injection ◽

Mouse Melanoma ◽

Mouse Melanoma Model ◽

Download Full-text

Transforming growth factor-β1 inhibits tumor growth in a mouse melanoma model by down-regulating the plasminogen activation system

Experimental Cell Research ◽

10.1016/s0014-4827(03)00336-7 ◽

2003 ◽

Vol 291 (1) ◽

pp. 1-10 ◽

Author(s):

Laurent Ramont ◽

Sylvie Pasco ◽

William Hornebeck ◽

François-Xavier Maquart ◽

Jean Claude Monboisse

Keyword(s):

Growth Factor ◽

Tumor Growth ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β1 ◽

Plasminogen Activation ◽

Mouse Melanoma ◽

Plasminogen Activation System ◽

Activation System ◽

Mouse Melanoma Model ◽

Download Full-text