Dysfunction of epithelial permeability barrier induced by HMGB1 in 2.5D cultures of human epithelial cells

2021 ◽  
Author(s):  
Takashi Kojima ◽  
Yuma Shindo ◽  
Takumi Konno ◽  
Yuki Kodera ◽  
Wataru Arai ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Permeability Barrier ◽  
Epithelial Permeability ◽  
Human Epithelial Cells

scholarly journals A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents

2021 ◽  
pp. 105122
Author(s):  
Thuc Nguyen Dan Do ◽  
Kim Donckers ◽  
Laura Vangeel ◽  
Arnab K. Chatterjee ◽  
Philippe A. Gallay ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Antiviral Agents ◽  
Liquid Interface ◽  
Human Epithelial Cells ◽  
Replication Model ◽  
Air Liquid Interface

scholarly journals Investigating the Responses of Human Epithelial Cells to Predatory Bacteria

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Ajay K. Monnappa ◽  
Wasimul Bari ◽  
Seong Yeol Choi ◽  
Robert J. Mitchell
Keyword(s):  
Epithelial Cells ◽  
Human Epithelial Cells ◽  
Predatory Bacteria

Calcyclin as a marker of human epithelial cells and fibroblasts

1992 ◽  
Vol 200 (2) ◽  
pp. 425-430 ◽  
Author(s):  
J. Kuźnicki ◽  
J. Kordowska ◽  
M. Puzianowska ◽  
B.M. Woźniewicz
Keyword(s):  
Epithelial Cells ◽  
Human Epithelial Cells

scholarly journals Differential Mucin Expression by Respiratory Syncytial Virus and Human Metapneumovirus Infection in Human Epithelial Cells

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Ma. Del Rocío Baños-Lara ◽  
Boyang Piao ◽  
Antonieta Guerrero-Plata
Keyword(s):  
Immune Response ◽  
Respiratory Syncytial Virus ◽  
Epithelial Cells ◽  
Viral Infections ◽  
Human Metapneumovirus ◽  
Human Epithelial Cells ◽  
Mucin Expression ◽  
Rsv Infection ◽  
Syncytial Virus ◽  
Tract Disease

Mucins (MUC) constitute an important component of the inflammatory and innate immune response. However, the expression of these molecules by respiratory viral infections is still largely unknown. Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two close-related paramyxoviruses that can cause severe low respiratory tract disease in infants and young children worldwide. Currently, there is not vaccine available for neither virus. In this work, we explored the differential expression of MUC by RSV and hMPV in human epithelial cells. Our data indicate that the MUC expression by RSV and hMPV differs significantly, as we observed a stronger induction of MUC8, MUC15, MUC20, MUC21, and MUC22 by RSV infection while the expression of MUC1, MUC2, and MUC5B was dominated by the infection with hMPV. These results may contribute to the different immune response induced by these two respiratory viruses.

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