scholarly journals Utility of neuroimaging in postpartum headache work-up: case report and diagnostic considerations

2013 ◽  
Vol 19 (3) ◽  
pp. 178-180
Author(s):  
VV Ajith ◽  
N Shetty ◽  
C Paul ◽  
P Reddy
Keyword(s):  
Case Report ◽  
Work Up ◽  
Postpartum Headache

scholarly journals Death of unknown cause? Post-mortem diagnosis of fulminant course of an EBV-associated secondary hemophagocytic lymphohistiocytosis

2021 ◽  
Author(s):  
Josia Fauser ◽  
Stefan Köck ◽  
Eberhard Gunsilius ◽  
Andreas Chott ◽  
Andreas Peer ◽  
...  
Keyword(s):  
Immune Response ◽  
Case Report ◽  
Macrophage Activation ◽  
Post Mortem ◽  
Life Threatening ◽  
Appropriate Therapy ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Secondary Hemophagocytic Lymphohistiocytosis

SummaryHLH is a life-threatening disease, which is characterized by a dysregulated immune response with uncontrolled T cell and macrophage activation. The often fulminant course of the disease needs a fast diagnostic work-up to initiate as soon as possible the appropriate therapy. We present herein the case of a 71-year-old patient with rapidly progressive hyperinflammatory syndrome, which post mortem resulted in the diagnosis of EBV-associated HLH. With this case report, we intend to highlight the relevance of the HScore in the diagnosis of HLH, to create a greater awareness for EBV as a trigger of HLH, and to demonstrate the importance of treating EBV-associated HLH as early as possible.

Limitations of rapid diagnostic testing in the work-up of dengue infection – a case report

2020 ◽  
Vol 58 (10) ◽  
pp. e245-e246
Author(s):  
Shaun S. Tan ◽  
Sharon Saw ◽  
Gabriel Yan ◽  
Ai Teng Chong ◽  
Zhixin Yang ◽  
...  
Keyword(s):  
Case Report ◽  
Dengue Infection ◽  
Diagnostic Testing ◽  
Rapid Diagnostic Testing ◽  
Work Up

scholarly journals Chikungunya virus and dengue virus coinfection: a case report from Bangladesh

2018 ◽  
Vol 12 (1) ◽  
pp. 42-43
Author(s):  
Muhammad Abdur Rahim ◽  
Shahana Zaman ◽  
Samira Rahat Afroze ◽  
Hasna Fahmima Haque ◽  
Farhana Afroz ◽  
...  
Keyword(s):  
Case Report ◽  
Virus Infection ◽  
Dengue Virus ◽  
Chikungunya Virus ◽  
Dengue Virus Infection ◽  
Emerging Infection ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Body Ache

A case of concurrent chikungunya virus and dengue virus infection is reported here. The patient presented with fever and generalized body ache. Diagnostic work-up revealed chikungunya-dengue co-infection. Dengue is endemic in Bangladesh while chikungunya is a recently emerging infection. As both the viruses are transmitted by a common vector, Aedes spp., such co-infections are likely to increase in coming years.IMC J Med Sci 2018; 12(1): 42-43

scholarly journals Complete Remission of Advanced Adrenocortical Cancer Following Mitotane Monotherapy: A Case Report and Literature Review of Predictive Markers

2021 ◽  
Vol 11 ◽  
Author(s):  
Judit Tőke ◽  
Zsuzsanna Jakab ◽  
Júlia Stark ◽  
Gergely Huszty ◽  
Péter Reismann ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Complete Remission ◽  
Vascular Invasion ◽  
Ct Scans ◽  
Adrenocortical Cancer ◽  
High Power Field ◽  
Predictors Of Response ◽  
Number Of Patients ◽  
Work Up

Mitotane has been used for the treatment of adrenocortical cancer (ACC) for over 50 years. Despite its widespread use both in monotherapy and in combination with chemotherapeutics, our knowledge of its mechanism of action and therapeutic efficacy is scarce. The number of patients with advanced ACC who have achieved complete remission documented by detailed clinical data is below ten. We report a case of a 64-year-old woman with a non-functional ACC. Histological examination showed vascular invasion, Ki67 of 10% and a mitotic count of 3/10 high-power field. Immunohistochemistry revealed p53 positivity. Pathological TNM grade was reported as T2N0M0, ENSAT stage 2. Nine months after the initial diagnosis, re-staging CT revealed multiple peritoneal nodules, lymph node and kidney metastases confirmed by histologic examination. Mitotane monotherapy was started with a maintenance dose between 2.0 and 2.5 grams/day. Partial remission was established at six months. Subsequently, for another 12 months, each of the three-monthly CT scans confirmed complete remission. Nineteen months after the initiation of mitotane, an unexpected sudden death occurred. A detailed autopsy work-up, performed in the full awareness of oncological history, confirmed complete remission. The authors review the molecular biomarkers and clinical features reported as predictors of response to mitotane monotherapy.

scholarly journals Lipoma Arborescens in a 16-year old male: A case report

2021 ◽  
Author(s):  
Paa BAIDOO ◽  
Emile Tano ◽  
Frank Nketiah Boakye ◽  
Majeedallahi Al-hassan ◽  
Gaddiel Yorke ◽  
...  
Keyword(s):  
Case Report ◽  
Range Of Motion ◽  
Laboratory Analysis ◽  
Incisional Biopsy ◽  
Lipoma Arborescens ◽  
Plain Radiographs ◽  
Adults And Children ◽  
Joint Effusions ◽  
Work Up

Lipoma arborescens is a benign intra-articular tumor characterized by joint effusions, pain and reduced range of motion. It is rare in adults and children. We present a case of Lipoma arborescens in a 16 year old male. The work up involved plain radiographs, MRI, incisional biopsy and laboratory analysis.

scholarly journals Parkes-Weber syndrome in the emergency department

2021 ◽  
Vol 14 (9) ◽  
pp. e241649
Author(s):  
Raj Patel ◽  
Edward James Durant ◽  
Robert Freed
Keyword(s):  
Emergency Department ◽  
Interventional Radiology ◽  
Case Report ◽  
Vascular Malformations ◽  
Weber Syndrome ◽  
The Common ◽  
Work Up

This case report describes a 20-year-old woman presenting to the emergency department (ED) with unilateral leg swelling. After multiple visits to the ED and workups with rheumatology, dermatology, interventional radiology and genetics, she was finally diagnosed with Parkes-Weber syndrome. The purpose of this case report is to illustrate the common and uncommon presentations, mimickers and work-up of Parkes-Weber syndrome as well as provide a brief overview of vascular malformations in general.

scholarly journals Spinal Brucellosis: A Case Report and Review of the Literature

2021 ◽  
Vol 11 (3) ◽  
Author(s):  
James M Rizkalla ◽  
Khalid Alhreish ◽  
Ishaq Y Syed
Keyword(s):  
Case Report ◽  
Signs And Symptoms ◽  
Radiographic Findings ◽  
Common Location ◽  
Uncommon Case ◽  
Spine Surgeon ◽  
Patient’S History ◽  
Hispanic Male ◽  
Work Up ◽  
Rare Diagnosis

Introduction: The most common location of infection of brucellosis is the musculoskeletal system. It is estimated that the spine is involved in 2–54% of brucellosis infections, with the lumbar spine most commonly affected. We report an uncommon case of brucellar spondylodiscitis, in addition to the pathology, common presentation, and management of spinal brucellosis through additional literature review. Case Report: A 65-year-old Hispanic male presented to an orthopedic spine surgeon with signs and symptoms concerning for metastatic disease to the spine. Investigation revealed that the patient had the rare diagnosis of brucellar spondylodiscitis. This only became apparent after detailed questioning of the patient’s history revealed his employment within a Mexican meat slaughterhouse and a regular consumer of unpasteurized Mexican cheeses. Conclusion: Although uncommon, brucellosis spondylodiscitis should remain as a differential diagnosis in any patient who presents with back pain and fever. Detailed history taking and thorough physical examination remain vital in the work-up of brucellar spondylodiscitis. Understanding the pathology, radiographic findings, and necessary work-up are essential to properly treat this infection. Keywords: Spine, Brucella, spinal brucellosis, infection, spondylodiscitis, discitis, abscess.

scholarly journals Rhino- Orbito- Cerebral- Mucormycosis with Osteomyelitis in a Patient with Diabetes mellitus: A Case Report and Literature Review

2012 ◽  
Vol 2 (2) ◽  
pp. 124-128 ◽  
Author(s):  
Rumana Habib ◽  
Rashedul Islam ◽  
Aminur Rahman ◽  
NB Bhowmik ◽  
Amirul Haque
Keyword(s):  
Case Report ◽  
Fungal Infection ◽  
Acquired Immunodeficiency Syndrome ◽  
Hematologic Malignancies ◽  
Successful Management ◽  
Acquired Immunodeficiency ◽  
Diagnostic Work ◽  
Immunodeficiency Syndrome ◽  
Work Up ◽  
Diagnostic Work Up

Mucormycosis is a form of fulminant invasive fungal infection of the sinonasal tract that often extends to the orbit, brain, palate, and skin. It is caused by members of the order Mucorales, and it is considered to be the most fatal fungal infection known to man. It is most commonly associated with diabetic ketoacidosis, hematologic malignancies, acquired immunodeficiency syndrome acquired immunodeficiency syndrome, see AIDS. , and immunosuppressive therapy. This rare opportunistic infection exists in many forms, the most common of which is rhinocerebral mucormycosis. Treatment includes aggressive surgical debridement of the necrotic tissue combined with systemic antifungal therapy. In this case report, we describe the successful management of rhinoorbitocerebral mucormycosis, a subtype of the rhinocerebral variety, complicated by osteomyelitis of cranium. We review the diagnostic work-up and discuss the literature with respect to the presentation, pathophysiology, management, and outcome of the disease.DOI: http://dx.doi.org/10.3329/birdem.v2i2.12331(Birdem Med J 2012; 2(2):124-127)

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