Limitations of rapid diagnostic testing in the work-up of dengue infection – a case report

2020 ◽  
Vol 58 (10) ◽  
pp. e245-e246
Author(s):  
Shaun S. Tan ◽  
Sharon Saw ◽  
Gabriel Yan ◽  
Ai Teng Chong ◽  
Zhixin Yang ◽  
...  
Keyword(s):  
Case Report ◽  
Dengue Infection ◽  
Diagnostic Testing ◽  
Rapid Diagnostic Testing ◽  
Work Up

scholarly journals Death of unknown cause? Post-mortem diagnosis of fulminant course of an EBV-associated secondary hemophagocytic lymphohistiocytosis

2021 ◽  
Author(s):  
Josia Fauser ◽  
Stefan Köck ◽  
Eberhard Gunsilius ◽  
Andreas Chott ◽  
Andreas Peer ◽  
...  
Keyword(s):  
Immune Response ◽  
Case Report ◽  
Macrophage Activation ◽  
Post Mortem ◽  
Life Threatening ◽  
Appropriate Therapy ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Secondary Hemophagocytic Lymphohistiocytosis

SummaryHLH is a life-threatening disease, which is characterized by a dysregulated immune response with uncontrolled T cell and macrophage activation. The often fulminant course of the disease needs a fast diagnostic work-up to initiate as soon as possible the appropriate therapy. We present herein the case of a 71-year-old patient with rapidly progressive hyperinflammatory syndrome, which post mortem resulted in the diagnosis of EBV-associated HLH. With this case report, we intend to highlight the relevance of the HScore in the diagnosis of HLH, to create a greater awareness for EBV as a trigger of HLH, and to demonstrate the importance of treating EBV-associated HLH as early as possible.

Paroxysmal localized Hyperhidrosis, a case-report: When excessive sweating occurs in combination with severe headaches

Cephalalgia ◽  
2021 ◽  
pp. 033310242110068
Author(s):  
Marleen H van Coevorden ◽  
Mariëtte WCJ Schoofs ◽  
Jeroen Venhovens
Keyword(s):  
Nervous System ◽  
Case Report ◽  
Autonomic Nervous System ◽  
Diagnostic Testing ◽  
Abdominal Ultrasound ◽  
Severe Headache ◽  
Excessive Sweating ◽  
Autonomic Nervous ◽  
Underlying Disorder ◽  
System Disorder

Background Paroxysmal localized hyperhidrosis is a rare disorder of the central autonomic nervous system. No association between paroxysmal hyperhidrosis and severe headache has been previously described in literature. Case description: A 65-year-old woman with idiopathic paroxysmal localized hyperhidrosis combined with severe holocranial headache attacks is described in this case report. Extensive diagnostic testing by means of laboratory examinations, 24-hour urinalyses, chest X-ray, abdominal ultrasound and computed tomography scans, and brain and spinal cord magnetic resonance imaging could not identify an underlying disorder. A diagnosis of idiopathic paroxysmal localized hyperhidrosis was made, and the patient was successfully treated with clonidine 0.075 mg three times a day, without any side effects. Conclusion Paroxysmal localized hyperhidrosis is a rare central autonomic nervous system disorder that can occur in combination with severe headache. Both the headache and paroxysmal hyperhidrosis complaints were treated effectively with clonidine in the patient described in this case-report.

Emergence of myasthenia gravis in dengue infection—first case report

2021 ◽  
Vol 27 (1) ◽  
pp. 183-185
Author(s):  
Yue Hui Lau ◽  
Suganthi Chinnasami
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Dengue Infection ◽  
First Case

scholarly journals Implementation of a Pharmacist-Directed Antimicrobial Stewardship Protocol Utilizing Rapid Diagnostic Testing

2016 ◽  
Vol 51 (10) ◽  
pp. 815-822 ◽  
Author(s):  
Angel Heyerly ◽  
Ron Jones ◽  
Gordon Bokhart ◽  
Mary Shoaff ◽  
Douglas Fisher
Keyword(s):  
Antimicrobial Stewardship ◽  
Diagnostic Testing ◽  
Rapid Diagnostic Testing

scholarly journals Chikungunya virus and dengue virus coinfection: a case report from Bangladesh

2018 ◽  
Vol 12 (1) ◽  
pp. 42-43
Author(s):  
Muhammad Abdur Rahim ◽  
Shahana Zaman ◽  
Samira Rahat Afroze ◽  
Hasna Fahmima Haque ◽  
Farhana Afroz ◽  
...  
Keyword(s):  
Case Report ◽  
Virus Infection ◽  
Dengue Virus ◽  
Chikungunya Virus ◽  
Dengue Virus Infection ◽  
Emerging Infection ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Body Ache

A case of concurrent chikungunya virus and dengue virus infection is reported here. The patient presented with fever and generalized body ache. Diagnostic work-up revealed chikungunya-dengue co-infection. Dengue is endemic in Bangladesh while chikungunya is a recently emerging infection. As both the viruses are transmitted by a common vector, Aedes spp., such co-infections are likely to increase in coming years.IMC J Med Sci 2018; 12(1): 42-43

scholarly journals Operational evaluation of rapid diagnostic testing for Ebola Virus Disease in Guinean laboratories

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0188047 ◽  
Author(s):  
Amanda VanSteelandt ◽  
Josephine Aho ◽  
Kristyn Franklin ◽  
Jacques Likofata ◽  
Jean Baptiste Kamgang ◽  
...  
Keyword(s):  
Ebola Virus ◽  
Virus Disease ◽  
Diagnostic Testing ◽  
Ebola Virus Disease ◽  
Rapid Diagnostic Testing

scholarly journals Complete Remission of Advanced Adrenocortical Cancer Following Mitotane Monotherapy: A Case Report and Literature Review of Predictive Markers

2021 ◽  
Vol 11 ◽  
Author(s):  
Judit Tőke ◽  
Zsuzsanna Jakab ◽  
Júlia Stark ◽  
Gergely Huszty ◽  
Péter Reismann ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Complete Remission ◽  
Vascular Invasion ◽  
Ct Scans ◽  
Adrenocortical Cancer ◽  
High Power Field ◽  
Predictors Of Response ◽  
Number Of Patients ◽  
Work Up

Mitotane has been used for the treatment of adrenocortical cancer (ACC) for over 50 years. Despite its widespread use both in monotherapy and in combination with chemotherapeutics, our knowledge of its mechanism of action and therapeutic efficacy is scarce. The number of patients with advanced ACC who have achieved complete remission documented by detailed clinical data is below ten. We report a case of a 64-year-old woman with a non-functional ACC. Histological examination showed vascular invasion, Ki67 of 10% and a mitotic count of 3/10 high-power field. Immunohistochemistry revealed p53 positivity. Pathological TNM grade was reported as T2N0M0, ENSAT stage 2. Nine months after the initial diagnosis, re-staging CT revealed multiple peritoneal nodules, lymph node and kidney metastases confirmed by histologic examination. Mitotane monotherapy was started with a maintenance dose between 2.0 and 2.5 grams/day. Partial remission was established at six months. Subsequently, for another 12 months, each of the three-monthly CT scans confirmed complete remission. Nineteen months after the initiation of mitotane, an unexpected sudden death occurred. A detailed autopsy work-up, performed in the full awareness of oncological history, confirmed complete remission. The authors review the molecular biomarkers and clinical features reported as predictors of response to mitotane monotherapy.

scholarly journals Lipoma Arborescens in a 16-year old male: A case report

2021 ◽  
Author(s):  
Paa BAIDOO ◽  
Emile Tano ◽  
Frank Nketiah Boakye ◽  
Majeedallahi Al-hassan ◽  
Gaddiel Yorke ◽  
...  
Keyword(s):  
Case Report ◽  
Range Of Motion ◽  
Laboratory Analysis ◽  
Incisional Biopsy ◽  
Lipoma Arborescens ◽  
Plain Radiographs ◽  
Adults And Children ◽  
Joint Effusions ◽  
Work Up

Lipoma arborescens is a benign intra-articular tumor characterized by joint effusions, pain and reduced range of motion. It is rare in adults and children. We present a case of Lipoma arborescens in a 16 year old male. The work up involved plain radiographs, MRI, incisional biopsy and laboratory analysis.

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