Successful preconceptional prophylactic treatment with combined acetyl salicylic acid and low-molecular heparin (Fragmin ® ) in a case of antiphospholipid-antibody syndrome with prior life-threatening hemolysis, elevated liver enzymes and low-platelet syndrome: a case report

2005 ◽  
Vol 84 (12) ◽  
pp. 1213-1214
Author(s):  
Kjell Haram ◽  
Line Björge ◽  
Per Morten Sandset
Open Medicine ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. 509-511
Author(s):  
Caiyuan Mai ◽  
Bin Wang ◽  
Rong Chen ◽  
Dongmei Duan ◽  
Lijuan Lv ◽  
...  

AbstractHELLP syndrome is a combination of symptoms described as hemolysis, elevated liver enzymes and low platelets. HELLP is a common life-threatening complication of pregnancy thought to be a variant or complication of preeclampsia. In this case report, we aimed to present a woman with acute postpartum HELLP syndrome complicated by pulmonary edema after caesarean section following severe preeclampsia. Our experience suggests that early detection of HELLP syndrome and timely management will bring good outcomes.


2001 ◽  
Vol 77 (6) ◽  
pp. 517-21
Author(s):  
Célia S. Macedo ◽  
Roberta S. Martinez ◽  
Márcia C. Riyuzo ◽  
Herculano D. Bastos

2001 ◽  
Vol 53 (4) ◽  
pp. 237-243
Author(s):  
Mohamed Z. Gad ◽  
Mahmoud M. Khattab ◽  
Nadia A. Moustafa ◽  
Jean-Luc Burgaud

Hematology ◽  
2018 ◽  
Vol 2018 (1) ◽  
pp. 313-317 ◽  
Author(s):  
John M. Gansner ◽  
Nancy Berliner

Abstract Catastrophic antiphospholipid antibody syndrome (CAPS) and macrophage activation syndrome (MAS) are both life-threatening hematologic disorders that infrequently afflict patients with rheumatologic disease. CAPS is characterized by fulminant multiorgan damage related to small vessel thrombosis in the setting of persistent antiphospholipid antibodies. It can occur in patients with rheumatologic diseases such as systemic lupus erythematosus but can also affect patients who do not have rheumatologic disease. By contrast, the term MAS is applied when patients with rheumatologic disease develop hemophagocytic lymphohistiocytosis (HLH); therefore, patients with MAS have an underlying rheumatologic disease by definition. Similar to CAPS, HLH/MAS can have a fulminant presentation, but the pathogenesis and manifestations are different. In both CAPS and MAS, management generally includes but is not limited to immunosuppression with steroids. Fatalities are relatively common and morbidity is often significant. Early recognition of these disorders and initiation of timely treatment are important. More effective therapies for both syndromes are urgently needed.


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