scholarly journals THE ISOLATION OF AN O SPECIFIC SUBSTANCE FROM GASTRIC JUICE OF SECRETORS AND CARBOHYDRATE-LIKE SUBSTANCES FROM GASTRIC JUICE OF NON-SECRETORS

1941 ◽  
Vol 73 (5) ◽  
pp. 655-667 ◽  
Author(s):  
Ernest Witebsky ◽  
Niels C. Klendshoj
Keyword(s):  
B Cells ◽  
Red Blood Cells ◽  
Gastric Juice ◽  
Blood Cells ◽  
Blood Groups ◽  
Human Beings ◽  
Human Red Blood Cells ◽  
Carbohydrate Fraction ◽  
Specific Substance ◽  
Group B

1. The isolation of a group specific O substance from the gastric juice of human beings belonging to group O is described. Absorbed normal beef serum constitutes the anti-O reagent. 2. The O specific substance inhibits the agglutination of human red blood cells belonging to group O. The agglutination of A cells by the isoagglutinin anti-A, or B cells by the isoagglutinin anti-B, is not influenced by the O substance. 3. The A and B specific substances isolated from human gastric juices inhibit the agglutination of O cells by absorbed normal beef serum, frequently to about the same extent as does the O substance itself. 4. The carbohydrate fraction isolated from the gastric juice of non-secretors belonging to group B does not inhibit the agglutination of human red blood cells of group B by the isoagglutinin anti-B nor the agglutination of O cells by the anti-O reagent. The significance of these findings for the conception of the nature of the blood groups and their inheritance is discussed.

scholarly journals Distribution of Blood Groups in Medical Students: A Comparative Study

2020 ◽  
Vol 8 (1) ◽  
pp. 42-46
Author(s):  
Bishal Joshi ◽  
Sanjit Kumar Kar ◽  
Shankar Yadav ◽  
Prem Kumar Yadav ◽  
Narayan Bahadur Mahotra ◽  
...  
Keyword(s):  
Medical Students ◽  
Red Blood Cells ◽  
Blood Group ◽  
Blood Cells ◽  
Blood Groups ◽  
Test Method ◽  
Fetal Life ◽  
Human Red Blood Cells ◽  
Slide Test ◽  
Group B

INTRODUCTION: Blood groups depend on antigens present on the surface of red blood cells. Scientists have discovered at least 30 common antigens and hundreds of rare antigens causing antigen-antibody reaction in human red blood cells. These antigens are genetically determined and are developed in fetal life and remain unchanged till death. Many blood group systems are identified but ABO and Rh blood groups are more antigenic. MATERIAL AND METHODS: In the present study, we observed ABO and Rh blood groups of 3057 students who studied in Universal College of Medical Sciences, Bhairahawa, Nepal from 1998 AD to 2019 AD, using open slide test method. The data was analyzed using SPSS version 20. RESULTS: Results  of the present study indicated that the most common blood group was O (36.8%)  followed by blood group B (31.1%) and blood group A (24.9%) and least common blood group was AB (7.2%) i.e. O>B>A>AB. The same sequence of ABO blood grouping was seen in both male and female.  Rh positive blood group was found in 95.4% and Rh negative blood group was found in 4.6% of population. CONCLUSION: Knowledge of distribution of blood group is very important for medical students as they can serve as immediate blood donor in emergency conditions. This study can provide insight to advanced studies in future which can relate blood groups with medical conditions.

scholarly journals Transbilayer distribution and mobility of phosphatidylinositol in human red blood cells.

1990 ◽  
Vol 265 (27) ◽  
pp. 16035-16038 ◽  
Author(s):  
P Bütikofer ◽  
Z W Lin ◽  
D T Chiu ◽  
B Lubin ◽  
F A Kuypers
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Human Red Blood Cells

scholarly journals Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ratnasekhar Ch ◽  
Guillaume Rey ◽  
Sandipan Ray ◽  
Pawan K. Jha ◽  
Paul C. Driscoll ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Mammalian Cells ◽  
Metabolic Flux ◽  
Pentose Phosphate ◽  
Human Red Blood Cells ◽  
Integral Process ◽  
Metabolic Oscillations ◽  
Human Rbcs

AbstractCircadian clocks coordinate mammalian behavior and physiology enabling organisms to anticipate 24-hour cycles. Transcription-translation feedback loops are thought to drive these clocks in most of mammalian cells. However, red blood cells (RBCs), which do not contain a nucleus, and cannot perform transcription or translation, nonetheless exhibit circadian redox rhythms. Here we show human RBCs display circadian regulation of glucose metabolism, which is required to sustain daily redox oscillations. We found daily rhythms of metabolite levels and flux through glycolysis and the pentose phosphate pathway (PPP). We show that inhibition of critical enzymes in either pathway abolished 24-hour rhythms in metabolic flux and redox oscillations, and determined that metabolic oscillations are necessary for redox rhythmicity. Furthermore, metabolic flux rhythms also occur in nucleated cells, and persist when the core transcriptional circadian clockwork is absent in Bmal1 knockouts. Thus, we propose that rhythmic glucose metabolism is an integral process in circadian rhythms.

scholarly journals Author Correction: Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Diego Sbardella ◽  
Grazia Raffaella Tundo ◽  
Luisa Campagnolo ◽  
Giuseppe Valacchi ◽  
Augusto Orlandi ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Rett Syndrome ◽  
Blood Cells ◽  
Human Red Blood Cells

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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