scholarly journals A COMPARISON OF ERYTHROCYTE SEDIMENTATION RATES AND ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD

1942 ◽  
Vol 75 (1) ◽  
pp. 119-126 ◽  
Author(s):  
Theodore Shedlovsky ◽  
John Scudder

Electrophoretic studies and erythrocyte sedimentation rate measurements were carried out on normal and pathological human blood. An increase in α globulin levels appears to take place, as well as an increase in sedimentation rates, when there is present any considerable inflammation or tissue destruction, irrespective of its cause. A graphic correlation is presented between sedimentation rates and α globulin levels, which is at least as good as a similar correlation involving fibrinogen levels.

1976 ◽  
Vol 10 (1) ◽  
pp. 39-46 ◽  
Author(s):  
G. W. Tribe ◽  
A. E. Welburn

2 batches of baboon infected with tuberculosis were subjected to serial tests with human and bovine tuberculin, while erythrocyte sedimentation rates were estimated concurrently. In the very early stages most but not all reacted to human tuberculin while fewer responded to bovine material. After further development of the disease, tuberculin tests remained positive while sedimentation rates were raised by 10-30 mm per hour. By the time early spread had occurred response to tuberculin was absent but sedimentation rates tended to increase. Advanced cases were always tuberculin negative but sedimentation rates were in excess of 50 mm per hour. Such animals were always in good physical condition and represented an insidious danger to other animals and staff in contact with them. Clinical examination failed to reveal cases of tuberculosis except in the terminal stages and no cases were diagnosed by radiography. 2 animals died from apparent anaphylaxis following inoculation of both types of tuberculin. Results showed that use of one or other of these tests alone would not have made possible the elimination of infection.


2019 ◽  
Vol 6 (05) ◽  
pp. 4472-4473
Author(s):  
Kane Genser, MD ◽  
Charles R. Spillert PhD

The clumping of circulating blood cells in many diseases gives rise to serious complications.  The sed-rate has been used to monitor blood for these changes. The protective low molecular weight agent used in this study was found to suppress the elevated sed-rate values.


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