Glucono-Delta-Lactone Mitigates the Erythrocyte Sedimentation Rate of Human Blood

2019 ◽  
Vol 6 (05) ◽  
pp. 4472-4473
Author(s):  
Kane Genser, MD ◽  
Charles R. Spillert PhD
Keyword(s):  
Molecular Weight ◽  
Erythrocyte Sedimentation Rate ◽  
Human Blood ◽  
Sedimentation Rate ◽  
Blood Cells ◽  
Low Molecular Weight ◽  
Erythrocyte Sedimentation

The clumping of circulating blood cells in many diseases gives rise to serious complications.  The sed-rate has been used to monitor blood for these changes. The protective low molecular weight agent used in this study was found to suppress the elevated sed-rate values.

Society of Physicians at Kazan University

1927 ◽  
Vol 23 (1) ◽  
pp. 144-145
Keyword(s):  
Comparative Study ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Clinical Picture ◽  
Blood Cells ◽  
White Blood Cells ◽  
Not Given ◽  
Blood Picture ◽  
Erythrocyte Sedimentation

Session 9/Xll 1926. Prof. N. K. Goryaev: To estimate the content of white blood cells by smear (Schtzung). The report will be printed in "Kaz. Med. Jour.". Drs. N. Zakharov, N. Kudryashev and M. Aksyantsev: Experience in comparative study of immunobiological reactions in tbc clinic. Report, to be printed in Kaz. Med. Jour. Prof. P. N. Nikolaev pointed out about the report that it is impossible to perform all reactions studied by the reporters at the patient's bedside and that the doctor should never forget the personality of the patient in his work. Prof. N. K. Goryaev noted that a big drawback of the report was the lack of description of the clinical picture of the cases studied, as well as the fact that in parallel with the reactions studied the blood picture was not given. To study erythrocyte sedimentation rate Prof. Goryaev considers the Linzeamier's methodology inconvenient. In addition, Drs. Mastbaum and Aksyantsev commented on the reports.

scholarly journals A COMPARISON OF ERYTHROCYTE SEDIMENTATION RATES AND ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD

1942 ◽  
Vol 75 (1) ◽  
pp. 119-126 ◽  
Author(s):  
Theodore Shedlovsky ◽  
John Scudder
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Human Blood ◽  
Sedimentation Rate ◽  
Sedimentation Rates ◽  
Tissue Destruction ◽  
Electrophoretic Patterns ◽  
Erythrocyte Sedimentation ◽  
Similar Correlation ◽  
Erythrocyte Sedimentation Rates

Electrophoretic studies and erythrocyte sedimentation rate measurements were carried out on normal and pathological human blood. An increase in α globulin levels appears to take place, as well as an increase in sedimentation rates, when there is present any considerable inflammation or tissue destruction, irrespective of its cause. A graphic correlation is presented between sedimentation rates and α globulin levels, which is at least as good as a similar correlation involving fibrinogen levels.

Experiments on Rouleau Formation

1973 ◽  
Vol 51 (9) ◽  
pp. 690-699 ◽  
Author(s):  
D. Kernick ◽  
A. W. L. Jay ◽  
S. Rowlands ◽  
L. Skibo
Keyword(s):  
Red Blood Cells ◽  
Erythrocyte Sedimentation Rate ◽  
Linear Function ◽  
Sedimentation Rate ◽  
Blood Cells ◽  
Temperature Dependent ◽  
Experimental Conditions ◽  
Erythrocyte Sedimentation ◽  
Rouleau Formation ◽  
High Erythrocyte Sedimentation Rate

Rouleau formation was measured by an adaptation of an old method used by Ponder (1927, Q. J. Exp. Physiol. 16, 173–194). Blood was depleted of red cells to a low hematocrit. It was stirred under standardized conditions, and after various times, samples were examined by microscope. Mean rouleau length was taken as an index of rouleau formation. The method was used to observe changes of rouleau formation with time and temperature and with variations in erythrocyte sedimentation rate (E.S.R.). Under these experimental conditions, mean rouleau length increases with time up to 40 min. Over a range of hematocrit values between 0 and 4%, rouleau length is a linear function of hematocrit. At higher hematocrits random aggregations based on columnar units are seen. Rouleau formation is temperature dependent and maximum mean rouleau length occurs around 37 °C. Subjects with a high erythrocyte sedimentation rate tend to form long rouleaux. By exchanging red blood cells (R.B.C.) between two ABO Rh compatible patients with greatly differing E.S.R. and mean rouleau length, it was shown that the agent responsible was in the plasma and not on the R.B.C. The results were compared with a theory of aggregation which proved inadequate in some respects.

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