An electric detection of immunoglobulin G in the enzyme-linked immunosorbent assay using an indium oxide nanoparticle ion-sensitive field-effect transistor

2011 ◽  
Vol 22 (1) ◽  
pp. 015009 ◽  
Author(s):  
Dongjin Lee ◽  
Tianhong Cui
2011 ◽  
Vol 23 (10) ◽  
pp. 2327-2334 ◽  
Author(s):  
Oshri Vaknin ◽  
Bassam Khamaisi ◽  
Mordechay Mizrahi ◽  
Nurit Ashkenasy

2010 ◽  
Vol 2010 ◽  
pp. 1-6
Author(s):  
Shun Mao ◽  
Ganhua Lu ◽  
Kehan Yu ◽  
Junhong Chen

We study the protein viability on Au nanoparticles during an electrospray and electrostatic-force-directed assembly process, through which Au nanoparticle-antibody conjugates are assembled onto the surface of carbon nanotubes (CNTs) to fabricate carbon nanotube field-effect transistor (CNTFET) biosensors. Enzyme-linked immunosorbent assay (ELISA) and field-effect transistor (FET) measurements have been used to investigate the antibody activity after the nanoparticle assembly. Upon the introduction of matching antigens, the colored reaction from the ELISA and the change in the electrical characteristic of the CNTFET device confirm that the antibody activity is preserved during the assembly process.


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