scholarly journals A simple and effective assembly sequence design method

2021 ◽  
Vol 1983 (1) ◽  
pp. 012102
Author(s):  
Chao Shao ◽  
Yuanzi Zhou ◽  
Qiang Zhang ◽  
Yuhang Tang ◽  
Jun Jiang
Keyword(s):  
Design Method ◽  
Assembly Sequence ◽  
Sequence Design

Formulating and Searching Assembly Sequence Design Spaces to Increase the Utilization of Current Assembly Plant Resources

2006 ◽  
Author(s):  
Shilpitha Bomi Reddy ◽  
Zahed Siddique
Keyword(s):  
Recursive Partitioning ◽  
Product Family ◽  
Assembly Process ◽  
Assembly Sequence ◽  
Plant Resources ◽  
Effective Utilization ◽  
Sequence Design ◽  
Software Application ◽  
Assembly Plant ◽  
Assembly Sequences

Efficient procedures for generation of feasible assembly sequences and effective utilization of available assembly plant resources can greatly reduce the development time and cost for platforms for the new product family members. This paper presents a method application to generate feasible assembly sequences and an approach to select an assembly process that reduces the existing plant modification cost. Assembly sequence design space is combinatorial in nature. Mathematical models to solve the effects of constraints on these spaces and algorithms to efficiently enumerate feasible spaces are presented. An algorithm that selects assembly process that can reduce the modification cost of the existing assembly plant is developed. A software application that implements the method and algorithms is also presented. The program uses the concept of recursive partitioning of set of components to generate assembly sequence space. The assembly processes are then evaluated to determine the process that maximized resource utilization. The application of the proposed approach and software is demonstrated using automotive underbody front structure product family.

Integrative Design of Product Architecture and Assembly Process Plan

2019 ◽  
Author(s):  
Masato Toi ◽  
Kana Sawai ◽  
Masahide Kobayashi ◽  
Yutaka Nomaguchi ◽  
Kikuo Fujita
Keyword(s):  
Product Design ◽  
Design Method ◽  
Product Architecture ◽  
Assembly Process ◽  
Air Conditioner ◽  
Assembly Sequence ◽  
Process Plan ◽  
Modeling And Analysis ◽  
Analysis Scheme ◽  
Integrative Design

Abstract This paper proposes an integrative design method of product architecture and assembly process plan by introducing a matrix-based modeling and analysis scheme. Design structure matrix (DSM) has been used to analyze and design the conceptual structure of product architecture. An assembly sequence diagram, such as a fishbone diagram, has been used as a representation scheme of the assembly process in the design-for-assembly (DFA) framework. The method of this paper is composed of a DSM-based procedure for generating an assembly sequence plan and its integration with a DSM-based design method of product architecture. In this paper, after general meanings of integration in product design are reviewed, the overall method for integration and mathematical procedure for optimizing an assembly sequence plan by compromising with components modularity are described. The procedure for generating an assembly sequence plan is demonstrated with an example of a desktop stapler, and the integrative design is demonstrated with a case study of air-conditioner units. This paper concludes with some discussion on the role of the proposed framework toward the integrity of product design.

scholarly journals Integrated Synthesis of Assembly and Fixture Scheme for Properly Constrained Assembly

2004 ◽  
Author(s):  
Byungwoo Lee ◽  
Kazuhiro Saitou
Keyword(s):  
Design Method ◽  
Integrated Approach ◽  
Frame Structure ◽  
Assembly Sequence ◽  
Top Down ◽  
Initial Product ◽  
Critical Dimensions ◽  
Final Assembly ◽  
Assembly Fixture

This paper presents an integrated approach to design an assembly, fixture schemes and an assembly sequence, such that the dimensional integrity of the assembly is insensitive to the dimensional variations of individual parts. The adjustability of critical dimensions and the proper constraining of parts during assembly process are the keys in achieving the dimensional integrity of the final assembly. A top down design method is developed which recursively decomposes a lump of initial product geometry and fixture elements matching critical dimensions, into parts and fixtures. At each recursion, joints are assigned to the interfaces between two subassemblies to ensure parts and fixtures are properly constrained at every assembly step. A case study on a simple frame structure is presented to demonstrate the method.

Increasing the efficiency and accuracy of the ABACUS protein sequence design method

2019 ◽  
Vol 36 (1) ◽  
pp. 136-144 ◽  
Author(s):  
Peng Xiong ◽  
Xiuhong Hu ◽  
Bin Huang ◽  
Jiahai Zhang ◽  
Quan Chen ◽  
...  
Keyword(s):  
Protein Sequence ◽  
Design Method ◽  
Solvent Accessibility ◽  
Supplementary Information ◽  
Survey Method ◽  
Energy Functions ◽  
Sequence Design ◽  
Feature Spaces ◽  
Empirical Function ◽  
Representative Points

Abstract Motivation The ABACUS (a backbone-based amino acid usage survey) method uses unique statistical energy functions to carry out protein sequence design. Although some of its results have been experimentally verified, its accuracy remains improvable because several important components of the method have not been specifically optimized for sequence design or in contexts of other parts of the method. The computational efficiency also needs to be improved to support interactive online applications or the consideration of a large number of alternative backbone structures. Results We derived a model to measure solvent accessibility with larger mutual information with residue types than previous models, optimized a set of rotamers which can approximate the sidechain atomic positions more accurately, and devised an empirical function to treat inter-atomic packing with parameters fitted to native structures and optimized in consistence with the rotamer set. Energy calculations have been accelerated by interpolation between pre-determined representative points in high-dimensional structural feature spaces. Sidechain repacking tests showed that ABACUS2 can accurately reproduce the conformation of native sidechains. In sequence design tests, the native residue type recovery rate reached 37.7%, exceeding the value of 32.7% for ABACUS1. Applying ABACUS2 to designed sequences on three native backbones produced proteins shown to be well-folded by experiments. Availability and implementation The ABACUS2 sequence design server can be visited at http://biocomp.ustc.edu.cn/servers/abacus-design.php. Supplementary information Supplementary data are available at Bioinformatics online.

SEQUENCE DESIGN AND FOLDING DYNAMICS OF LATTICE PROTEIN-LIKE MODELS

2002 ◽  
Vol 16 (04) ◽  
pp. 631-637 ◽  
Author(s):  
MENG QIN ◽  
JUN WANG ◽  
TANPING LI ◽  
WEI WANG
Keyword(s):  
Great Improvement ◽  
Design Method ◽  
Protein Sequences ◽  
Target Structure ◽  
Dynamic Features ◽  
Sequence Design ◽  
Model Protein ◽  
Folding Dynamics

A sequence design method based on maximizing the thermodynamic occupying probability of the target structure is investigated. Some model-protein sequences are designed using the occupying-probability-maximized procedure on a 3×3×3 lattice. The thermodynamic and dynamic features of these sequences show their great improvement comparing with those of the sequences designed by an energy-minimized method. A better foldability is achieved for the occupying-probability-maximized sequences. These results suggest that the native occupying probability rather than the energy would be a better judgment for protein-like models.

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