scholarly journals Development of visual display and data transmission system for patients with chronic disorders of consciousness

2021 ◽  
Vol 2086 (1) ◽  
pp. 012080
Author(s):  
S A Degtiareva ◽  
D S Shiryaev ◽  
Y S Andreev ◽  
I S Polukhin ◽  
E A Kondratieva ◽  
...  
Keyword(s):  
Data Transmission ◽  
Human Error ◽  
Visual Display ◽  
Medical Emergency ◽  
Optoelectronic System ◽  
Biomedical Sensors ◽  
Life Threatening ◽  
Data Transmission System ◽  
Chronic Disorders ◽  
Chronic Disorders Of Consciousness

Abstract The monitoring is integral part for patients with chronic disorders, as such cases require serious attention to save their life and predict recovery. Physiological signs such as heart rate, hemodynamic, temperature, saturation are collected from biomedical sensors to bedside monitors that medical staff could detect unexpected life-threatening conditions being around the patients. However, it is a tough job to being stuck at monitor for every person. Furthermore, such continuous supervision may lead to difficulties due to human error. Thus there is a need to capture, display all physiological changes visually and give a medical emergency about health conditions when they are out of the normal range. The main objective is the development of the optoelectronic system for visual monitoring and data transmission of patients in a coma by optical wireless communication.

A Review on the Use of Reversal Agents of Direct Oral Anticogulant Drugs in Case of Gastrointestinal Bleeding

2020 ◽  
Vol 15 ◽  
Author(s):  
Veronica Ojetti ◽  
Angela Saviano ◽  
Mattia Brigida ◽  
Luisa Saviano ◽  
Alessio Migneco ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Major Bleeding ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Medical Emergency ◽  
Management Approach ◽  
Emergency Setting ◽  
Reversal Agents ◽  
Life Threatening ◽  
Andexanet Alfa

Background : Major bleeding is a life-threatening condition and a medical emergency with high mortality risk. It is often the complication of anticoagulant’s intake. Anticoagulants are commonly used for the prevention and the treatment of thrombotic events. The standard therapy with vitamin K antagonist (warfarin) has been frequently replaced by direct oral anticoagulants (DOACs). The latter agents (rivaroxaban, apixaban, edoxaban, dabigatran, betrixaban) showed a better efficacy and safety compared to standard warfarin treatment and they are recommended for the reduction of ischemic stroke. Literature data reported a high risk of gastrointestinal bleeding with DOACs, in particular with dabigatran and rivaroxaban. In case of life-threatening gastrointestinal bleeding, these patients could benefit from the use of reversal agents. Methods: We performed an electronic search on PUBMED of the literature concerning reversal agents for DOACs and gastrointestinal bleeding in the Emergency Department from 2004 to 2020. AIM: This review summarizes the current evidences about three reversal agents idarucizumab, andexanet alfa and ciraparantag, and the use of the first two in the emergency setting in patients with an active major bleeding or who need urgent surgery to offer physicians indications for a better management approach in order to increase patient’s safety. Conclusion: Although these agents have been marketed for five years (idarucizumab) and two years (andexanet alfa) respectively, and despite guidelines considering antidotes as first-line agents in treating life-threatening hemorrhage when available, these antidotes seem to gain access very slowly in the clinical practice. Cost, logistical aspects and need for plasma level determination of DOAC for an accurate therapeutic use probably have an impact on this phenomenon.. An expert multidisciplinary bleeding team should be established so as to implement international guidelines based on local resources and organization.

scholarly journals Ultrasonic thalamic stimulation in chronic disorders of consciousness

2021 ◽  
Vol 14 (2) ◽  
pp. 301-303
Author(s):  
Joshua A. Cain ◽  
Norman M. Spivak ◽  
John P. Coetzee ◽  
Julia S. Crone ◽  
Micah A. Johnson ◽  
...  
Keyword(s):  
Disorders Of Consciousness ◽  
Thalamic Stimulation ◽  
Chronic Disorders ◽  
Chronic Disorders Of Consciousness

Acute pericardial tamponade: The initial manifestation of systemic lupus erythematosus with Graves’ hyperthyroidism

Lupus ◽  
2021 ◽  
pp. 096120332110047
Author(s):  
Muming Yu ◽  
Yulei Gao ◽  
Heng Jin ◽  
Songtao Shou
Keyword(s):  
Myocardial Infarction ◽  
Systemic Lupus Erythematosus ◽  
Female Patient ◽  
Lupus Erythematosus ◽  
Pericardial Tamponade ◽  
Medical Emergency ◽  
Systemic Lupus ◽  
Initial Manifestation ◽  
Life Threatening ◽  
Obstructive Shock

Acute pericardial tamponade, which can cause obstructive shock, is a serious life-threatening medical emergency that can be readily reversed by timely identification and appropriate intervention. Acute pericardial tamponade can occur for a number of reasons, including idiopathic, malignancy, uremia, iatrogenic, post-myocardial infarction, infection, collagen vascular, hypothyroidism, and others. Systemic lupus erythematosus (SLE) and hyperthyroidism associated with pericardial tamponade are rarely reported. Here, we report the case of a 20-year-old female patient was final diagnosed of SLE with Graves’ hyperthyroidism.

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