scholarly journals Comparison of the effectiveness of blood transfusion and reinfusion

2021 ◽  
Vol 2086 (1) ◽  
pp. 012119
Author(s):  
E V Pimakhina ◽  
A A Pimakhin ◽  
N V Vishnykov ◽  
N M Tolkach ◽  
S B Arsentiev
Keyword(s):  
Blood Parameters ◽  
Cell Saver ◽  
Patient Blood Management ◽  
Blood Management ◽  
Massive Blood Loss ◽  
Atomic Force ◽  
Actual Solution ◽  
Morphological Defects ◽  
Quality Of Medical Care

Abstract Studies by atomic force and scanning electron microscopy have shown that erythrocytes of foreign blood have morphological defects. The sequestration of foreign erythrocytes makes it difficult for the erythron to selfrepair. The actual solution to this problem is the application of the blood reinfusion technique using the Cell Saver apparatus. Transfusion of autoerythra suspension, harvested using the Cell Saver apparatus during the operation, stabilizes red blood counts in the early post-transfusion period in patients and reduces the manifestation of massive hemotransfusion syndrome. Hardware reinfusion of erythrocytes is effective and safe for massive blood loss in obstetrics. Reinfusion dictates the need for parallel correction of all blood parameters. Application of the principles of patient blood management can reduce the transfusion load, improve the quality of medical care.

Patient Blood Management in Elective Total Hip- and Knee-replacement Surgery (Part 2)

2014 ◽  
Vol 120 (4) ◽  
pp. 852-860 ◽  
Author(s):  
Cynthia So-Osman ◽  
Rob G. H. H. Nelissen ◽  
Ankie W. M. M. Koopman-van Gemert ◽  
Ewoud Kluyver ◽  
Ruud G. Pöll ◽  
...  
Keyword(s):  
Knee Replacement ◽  
Control Group ◽  
Transfusion Rate ◽  
Cell Saver ◽  
Patient Blood Management ◽  
Blood Management ◽  
Knee Replacement Surgery ◽  
Total Hip ◽  
Replacement Surgery ◽  
Preoperative Hemoglobin

Abstract Background: Patient blood management is introduced as a new concept that involves the combined use of transfusion alternatives. In elective adult total hip- or knee-replacement surgery patients, the authors conducted a large randomized study on the integrated use of erythropoietin, cell saver, and/or postoperative drain reinfusion devices (DRAIN) to evaluate allogeneic erythrocyte use, while applying a restrictive transfusion threshold. Patients with a preoperative hemoglobin level greater than 13 g/dl were ineligible for erythropoietin and evaluated for the effect of autologous blood reinfusion. Methods: Patients were randomized between autologous reinfusion by cell saver or DRAIN or no blood salvage device. Primary outcomes were mean intra- and postoperative erythrocyte use and proportion of transfused patients (transfusion rate). Secondary outcome was cost-effectiveness. Results: In 1,759 evaluated total hip- and knee-replacement surgery patients, the mean erythrocyte use was 0.19 (SD, 0.9) erythrocyte units/patient in the autologous group (n = 1,061) and 0.22 (0.9) erythrocyte units/patient in the control group (n = 698) (P = 0.64). The transfusion rate was 7.7% in the autologous group compared with 8.3% in the control group (P = 0.19). No difference in erythrocyte use was found between cell saver and DRAIN groups. Costs were increased by €298 per patient (95% CI, 76 to 520). Conclusion: In patients with preoperative hemoglobin levels greater than 13 g/dl, autologous intra- and postoperative blood salvage devices were not effective as transfusion alternatives: use of these devices did not reduce erythrocyte use and increased costs.

Patient Blood Management in Elective Total Hip- and Knee-replacement Surgery (Part 1)

2014 ◽  
Vol 120 (4) ◽  
pp. 839-851 ◽  
Author(s):  
Cynthia So-Osman ◽  
Rob G. H. H. Nelissen ◽  
Ankie W. M. M. Koopman-van Gemert ◽  
Ewoud Kluyver ◽  
Ruud G. Pöll ◽  
...  
Keyword(s):  
Knee Replacement ◽  
Autologous Blood ◽  
Secondary Outcome ◽  
Transfusion Rate ◽  
Cell Saver ◽  
Patient Blood Management ◽  
Blood Management ◽  
Transfusion Threshold ◽  
Restrictive Transfusion ◽  
Blood Salvage

Abstract Background: Patient blood management combines the use of several transfusion alternatives. Integrated use of erythropoietin, cell saver, and/or postoperative drain reinfusion devices on allogeneic erythrocyte use was evaluated using a restrictive transfusion threshold. Methods: In a factorial design, adult elective hip- and knee-surgery patients with hemoglobin levels 10 to 13 g/dl (n = 683) were randomized for erythropoietin or not, and subsequently for autologous reinfusion by cell saver or postoperative drain reinfusion devices or for no blood salvage device. Primary outcomes were mean allogeneic intra- and postoperative erythrocyte use and proportion of transfused patients (transfusion rate). Secondary outcome was cost-effectiveness. Results: With erythropoietin (n = 339), mean erythrocyte use was 0.50 units (U)/patient and transfusion rate 16% while without (n = 344), these were 0.71 U/patient and 26%, respectively. Consequently, erythropoietin resulted in a nonsignificant 29% mean erythrocyte reduction (ratio, 0.71; 95% CI, 0.42 to 1.13) and 50% reduction of transfused patients (odds ratio, 0.5; 95% CI, 0.35 to 0.75). Erythropoietin increased costs by €785 per patient (95% CI, 262 to 1,309), that is, €7,300 per avoided transfusion (95% CI, 1,900 to 24,000). With autologous reinfusion, mean erythrocyte use was 0.65 U/patient and transfusion rate was 19% with erythropoietin (n = 214) and 0.76 U/patient and 29% without (n = 206). Compared with controls, autologous blood reinfusion did not result in erythrocyte reduction and increased costs by €537 per patient (95% CI, 45 to 1,030). Conclusions: In hip- and knee-replacement patients (hemoglobin level, 10 to 13 g/dl), even with a restrictive transfusion trigger, erythropoietin significantly avoids transfusion, however, at unacceptably high costs. Autologous blood salvage devices were not effective.

Patient Blood Management in der Orthopädie und Unfallchirurgie

2020 ◽  
Vol 15 (03) ◽  
pp. 239-255
Author(s):  
Lea Valeska Blum ◽  
Hendrik Kohlhof ◽  
Dieter Wirtz ◽  
Kai Zacharowski ◽  
Patrick Meybohm
Keyword(s):  
Patient Blood Management ◽  
Blood Management ◽  
Orthopädie Und Unfallchirurgie

REORGANIZATION OF A MULTI-SPECIALTY HOSPITAL IN AN UNFAVORABLE EPIDEMIOLOGICAL SITUATION

2020 ◽  
pp. 43-46
Author(s):  
Nikitin A.E. ◽  
Znamenskiy I.А ◽  
Shikhova Yu.A. ◽  
Kuzmina I.V. ◽  
Melchenko D.S. ◽  
...  
Keyword(s):  
Contact Time ◽  
Laboratory Diagnostics ◽  
Protective Equipment ◽  
Timely Manner ◽  
High Quality ◽  
Institu Tions ◽  
Quality Of Medical Care ◽  
Spread Of Infection ◽  
Epidemiological Situation

This study provides a retrospective analysis of work to ensure high quality of medical care in an unfavorable epidemic situation. The consequence of COVID-19 was the implementation of a program to prevent the spread of infection, the re-profiling of medical institu-tions, and the introduction of restrictive and anti-epidemic measures. The experience of our work has shown the effectiveness of changing the order of med-ical care, the organization of the functioning of de-partments and patient routing. The study reflects the measures implemented in the hospital departments, the Department of clinical and laboratory diagnostics, radiation diagnostics and pathology Department. To ensure the safety of patients, it was decided to place patients on a single bed according to the type of infec-tious boxes. The safety of employees was ensured by the use of personal protective equipment, minimiza-tion of contact time with patients, and preventive weekly examination of staff for SARS-CoV-2 infection. The organized and well-coordinated work of the en-tire staff of the institution made it possible to prevent the spread of COVID-19 among employees, to detect cases of infection in a timely manner, and to carry out appropriate isolation and monitoring measures. At the time of completion of infectious diseases departments, the mortality rate among patients was less than 9%. Our experience in reorganizing a multi-specialty facil-ity can be used in the future when working with pa-tients who have undergone COVID-19, as well as in the context of a worsening epidemic situation.

Responsibility for a quality of medical care provided via telemedicine

2018 ◽  
Vol 2018 (1-2) ◽  
pp. 9-15
Author(s):  
Morozov S.P. ◽  
◽  
Vladzymyrskyy A.V. ◽  
Varyushin M.S. ◽  
Aronov A.V. ◽  
...  
Keyword(s):  
Medical Care ◽  
Quality Of Medical Care

METHODOLOGICAL APPROACH TO EVALUATING THE EFFECTIVENESS OF RESOURCE USE BY MEDICAL ORGANIZATIONS

2020 ◽  
Vol 3 (7) ◽  
pp. 62-69
Author(s):  
S. S. BUDARIN ◽  
Keyword(s):  
Medical Care ◽  
Resource Use ◽  
Methodological Approach ◽  
Use Of Resources ◽  
Quality Of Medical Care ◽  
Methodological Approaches ◽  
Performance Audit ◽  
Available Resources

The article reveals methodological approaches to evaluating the effectiveness of the use of resources of medi-cal organizations in order to improve the availability and quality of medical care based on the application of the methodology of performance audit; a methodological approach to the use of individual elements of the efficiency audit methodology for evaluating the performance of medical organizations and the effectiveness of the use of available resources is proposed.

Sign in / Sign up

Export Citation Format

Share Document