In vivo performance of combinations of autograft, demineralized bone matrix, and tricalcium phosphate in a rabbit femoral defect model

2014 ◽  
Vol 9 (3) ◽  
pp. 035010 ◽  
Author(s):  
Jinku Kim ◽  
Sean McBride ◽  
David D Dean ◽  
Victor L Sylvia ◽  
Bruce A Doll ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Defect Model ◽  
Femoral Defect ◽  
Demineralized Bone

Induction of bone by a demineralized bone matrix gel: A study in a rat femoral defect model

1995 ◽  
Vol 13 (6) ◽  
pp. 881-891 ◽  
Author(s):  
John E. Feighan ◽  
Dwight Davy ◽  
Annamarie B. Prewett ◽  
Sharon Stevenson
Keyword(s):  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Defect Model ◽  
Femoral Defect ◽  
Demineralized Bone

In Vivo Bone Tissue Formation Induced by Caclium Phosphate Paste Composite with Demineralized Bone Matrix

2007 ◽  
Vol 330-332 ◽  
pp. 1091-1094
Author(s):  
H. Kim ◽  
M. Park ◽  
Su Young Lee ◽  
Kang Yong Lee ◽  
Hyun Min Kim ◽  
...  
Keyword(s):  
Animal Model ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Marker Gene ◽  
Tissue Formation ◽  
Bone Tissue Formation ◽  
Demineralized Bone

Demineralized bone matrix (DBM)-calcium phosphate cement (CPC) composites were subjected to cellular test of osteogenic potentials and implantation in animal model. The expression of osteogenic marker gene from mouse preosteoblast cell line MC3T3-E1 adhered to the DBM-CPC composite was much higher than plain CPC. In addition, the DBM-CPC composite implanted nude mice revealed osteoinduction between the implanted composite and adjacent tissues, whereas the plain CPC induced osteoconduction.

Preparation and In Vitro Characterization of Polycaprolactone and Demineralized Bone Matrix Scaffolds

2012 ◽  
Vol 1417 ◽  
Author(s):  
Titilayo Moloye ◽  
Christopher Batich
Keyword(s):  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Apatite Formation ◽  
Alizarin Red ◽  
Salt Leaching ◽  
Synthetic Materials ◽  
Calcium And Phosphorus ◽  
Demineralized Bone

ABSTRACTCylindrical porous polycaprolactone (PCL) scaffolds containing 25, 35, and 50 wt% demineralized bone matrix (DBM) were fabricated using a salt-leaching method for application in bone engineering. In the present work, PCL-DBM scaffolds were monitored for calcium and phosphorus deposition in both deionized (DI) water and simulated body fluid (SBF) for time periods of 5, 10, 15, and 20 days at 37°C under constant rotation. An in vitro assessment of the bioactivity of synthetic materials using SBF under physiological conditions can be used as a barometer of scaffold behavior in vivo. DBM, an osteoinductive material, was used to gauge if there was a correlation between the concentration of DBM within a scaffold and the apatite formation on its surface. Biochemical assays, alizarin red S staining, and scanning electron microscopy (SEM) with elemental analysis of calcium and phosphorus were consistent in that they confirmed that PCL scaffolds containing 35 wt% DBM in SBF at 14 days post-immersion showed signs of early apatite formation.

The Effect of Carrier Type on Bone Regeneration of Demineralized Bone Matrix In Vivo

2013 ◽  
Vol 24 (6) ◽  
pp. 2135-2140 ◽  
Author(s):  
Shima Tavakol ◽  
Ahad Khoshzaban ◽  
Mahmoud Azami ◽  
Iraj Ragerdi Kashani ◽  
Hani Tavakol ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Demineralized Bone
Sign in / Sign up

Export Citation Format

Share Document