Solution blow spinning of PLLA/Hydroxyapatite composite scaffolds for bone tissue engineering

2021 ◽  
Author(s):  
Arnold Popkov ◽  
Denis Kulbakin ◽  
Dmitry Popkov ◽  
Elena Gorbach ◽  
Natalia Kononovich ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Composite Scaffolds ◽  
Hydroxyapatite Composite ◽  
Solution Blow Spinning

scholarly journals Biomimetic cellulose/calcium-deficient-hydroxyapatite composite scaffolds fabricated using an electric field for bone tissue engineering

RSC Advances ◽  
2018 ◽  
Vol 8 (37) ◽  
pp. 20637-20647 ◽  
Author(s):  
MyoJin Kim ◽  
MiJi Yeo ◽  
Minseong Kim ◽  
GeunHyung Kim
Keyword(s):  
Tissue Engineering ◽  
Electric Field ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Processing Parameters ◽  
Composite Scaffolds ◽  
Mesh Structure ◽  
Ceramic Scaffold ◽  
Hydroxyapatite Composite

The fabricated ceramic scaffold showed a layer-by-layered mesh structure entangled with cellulose micro/nanofibers and the bioceramic phase. By varying processing parameters, the unique 3D fibrous mesh-structure could be achieved.

A study on the bioactivity of chitosan/nano-hydroxyapatite composite scaffolds for bone tissue engineering

2006 ◽  
Vol 42 (12) ◽  
pp. 3171-3179 ◽  
Author(s):  
Lijun Kong ◽  
Yuan Gao ◽  
Guangyuan Lu ◽  
Yandao Gong ◽  
Nanming Zhao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Composite Scaffolds ◽  
Hydroxyapatite Composite

Synthesis and characterisation of gelatin–nano hydroxyapatite composite scaffolds for bone tissue engineering

2008 ◽  
Vol 107 (1) ◽  
pp. 4-8 ◽  
Author(s):  
S. Mobini ◽  
J. Javadpour ◽  
M. Hosseinalipour ◽  
M. Ghazi-Khansari ◽  
A. Khavandi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Composite Scaffolds ◽  
Hydroxyapatite Composite

In Vitro Evaluation of Poly ε-Caprolactone/Hydroxyapatite Composite as Scaffolds for Bone Tissue Engineering with Human Bone Marrow Stromal Cells

2007 ◽  
Vol 342-343 ◽  
pp. 369-372 ◽  
Author(s):  
S.J. Heo ◽  
S.E. Kim ◽  
Yong Taek Hyun ◽  
D.H. Kim ◽  
Hyang Mi Lee ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Marrow ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Osteoblastic Differentiation ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Composite Scaffolds ◽  
Hydroxyapatite Composite

This study evaluated the potential of the PCL (poly -caprolactone)/HA(Hydroxyapatite) composite materials as a scaffold for bone regeneration. For this, we fabricated scaffolds utilizing salt leaching method. The PCL/HA composite scaffolds were prepared with various HA contents (20wt%, 40wt%, 60 wt %). To ensure the potential for the scaffolds, porosity tests were conducted along with SEM observations. The porosity decreased with the increase of the contents of HA particles. The porosity of the composite with the highest contents of HA was still adoptable (~85%). In addition, the PCL/HA composite scaffolds were evaluated for their ability of osteogenic differentiation with human bone marrow stromal cell (hBMSC) in vitro. Alkaline phosphatase (ALP) activity, markers for osteoblastic differentiation, and total protein contents were evaluated in hBMSCs following 14 days of cultivation. The addition of HA particles enhanced proliferation of hBMSC during the test. Also, the differentiation ability of the cells was increased as HA particles were added. In this study, we concluded that PCL/HA composite scaffolds has great potential as a scaffold for bone tissue engineering.

scholarly journals Excellency of Hydroxyapatite Composite Scaffolds for Bone Tissue Engineering

Biomaterials ◽  
2020 ◽  
Author(s):  
Mohammad Shariful Islam ◽  
Mohammad Abdulla-Al-Mamun ◽  
Alam Khan ◽  
Mitsugu Todo
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Surface Reactivity ◽  
Growth Factor Delivery ◽  
Composite Scaffolds ◽  
In Vivo Experiments ◽  
Hydroxyapatite Composite

The hydroxyapatite [HAp, Ca10(PO4)6(OH)2] has a variety of applications in bone fillers and replacements due to its excellent bioactivity and osteoconductivity. It comprises the main inorganic component of hard tissues. Among the various approaches, a composite approach using several components like biopolymer, gelatin, collagen, and chitosan in the functionalization of scaffolds with HAp has the prospective to be an engineered biomaterial for bone tissue engineering. HAp composite scaffolds have been developed to obtain a material with different functionalities such as surface reactivity, bioactivity, mechanical strength, and capability of drug or growth factor delivery. Several techniques and processes for the synthesis and fabrication of biocompatible HAp composite scaffolds suitable for bone regeneration are addressed here. Further, this chapter described the excellences of various HAp composite scaffolds used in in vitro and in vivo experiments in bone tissue engineering.

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