Inhibition of Growth and Induction of Apoptosis in Human Cancer Cell Lines by an Ethyl Acetate Fraction from Shiitake Mushrooms

2006 ◽  
Vol 12 (2) ◽  
pp. 125-132 ◽  
Author(s):  
Nianbai Fang ◽  
Qinglin Li ◽  
Shanggong Yu ◽  
Jianxiang Zhang ◽  
Ling He ◽  
...  
2002 ◽  
Vol 57 (11-12) ◽  
pp. 1092-1096 ◽  
Author(s):  
Françoise Lohézic-Le Dévéhat ◽  
Sophie Tomasi ◽  
Didier Fontanel ◽  
Joël Boustie

Three natural flavonols compounds have been isolated from the ethyl acetate fraction of Scurrula ferruginea Danser (Loranthaceae). Besides quercetin and quercitrin, an unusual flavonol glycoside 4″-O-acetylquercitrin was isolated. Structures were determined using spectroscopic methods including UV, NMR and HRMS-EI. The incidence of 4″-O-acetylquercitrin, not previously reported in the Loranthaceae, is discussed. Cytotoxic evaluation on four human cancer cell lines showed quercetin to be the most active with IC50 of 35 μм on U251 (human glioblastoma cells).


2011 ◽  
Vol 63 (5) ◽  
pp. 763-770 ◽  
Author(s):  
Akiko Inoue ◽  
Kimitaka Takitani ◽  
Maki Koh ◽  
Chihiro Kawakami ◽  
Tomoko Kuno ◽  
...  

2012 ◽  
Vol 34 (2) ◽  
pp. 397-408 ◽  
Author(s):  
Girish Beedessee ◽  
Avin Ramanjooloo ◽  
Geneviève Aubert ◽  
Laure Eloy ◽  
Rashmee Surnam-Boodhun ◽  
...  

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