Genetic Polymorphisms of PRNCR1 and Lung Cancer Risk in Chinese Northeast Population: A Case–Control Study and Meta-Analysis

2020 ◽  
Author(s):  
Na Li ◽  
Zhigang Cui ◽  
Min Gao ◽  
Sixuan Li ◽  
Mingyang Song ◽  
...  
Cytokine ◽  
2014 ◽  
Vol 65 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Chikako Kiyohara ◽  
Takahiko Horiuchi ◽  
Koichi Takayama ◽  
Yoichi Nakanishi

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0128201 ◽  
Author(s):  
Qi Wang ◽  
Juntao Ke ◽  
Qibin Song ◽  
Weiguo Hu ◽  
Xuzai Lu ◽  
...  

2017 ◽  
Vol 33 (2) ◽  
pp. 195-200 ◽  
Author(s):  
Xianhong Feng ◽  
Jingdong Wang ◽  
Xiuli Gu ◽  
Jingli Zhang ◽  
Xiaolin Li ◽  
...  

Purpose: To investigate the association of DNMT3B -283T>C polymorphism with the risk of lung or gastric cancer, which was followed by a meta-analysis. Methods: The genotyping of -283T>C was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and was confirmed by sequencing. Results: The results of this case-control study showed that -283T>C was not associated with the risk of lung or gastric cancer, and further stratified analysis according to age, gender, smoking status, and alcohol status confirmed the present finding. However, data from a meta-analysis in the Asian population revealed a significant association between -283T>C and lung cancer risk in the allelic model (C vs. T: odds ratio [OR] = 1.28, 95% confidence interval [CI], 1.06-1.55, p = 0.01) and two genetic models (CC vs. TC: OR = 1.29, 95% CI, 1.04-1.59, p = 0.02; CC vs. TC + TT: OR = 1.30, 95% CI, 1.06-1.60, p = 0.01). Conclusions: These results provided evidence that the DNMT3B -283T>C polymorphism might significantly contribute to the lung cancer risk in the Asian population, but not the gastric cancer risk in the Chinese population.


2004 ◽  
Vol 49 (2) ◽  
pp. 139-143 ◽  
Author(s):  
Pagona Lagiou ◽  
Evi Samoli ◽  
Areti Lagiou ◽  
Klea Katsouyanni ◽  
Julia Peterson ◽  
...  

Author(s):  
Valent�n Rodr�guez ◽  
Adonina Tard�n ◽  
Manolis Kogevinas ◽  
Carlos S. Prieto ◽  
Antonio Cueto ◽  
...  

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