Type 1 Interferon as an Antiinflammatory Agent: Inhibition of Lipopolysaccharide-Induced Interleukin-lβ and Induction of Interleukin-1 Receptor Antagonist

1995 ◽  
Vol 15 (4) ◽  
pp. 317-321 ◽  
Author(s):  
YANLING HUANG ◽  
LAWRENCE M. BLATT ◽  
MILTON W. TAYLOR
Keyword(s):  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Antiinflammatory Agent ◽  
Type 1 Interferon ◽  
Interleukin 1 Receptor Antagonist

scholarly journals Interleukin-1 Receptor Antagonist Gene Polymorphism and Circulating Levels of Human Immunodeficiency Virus Type 1 RNA in Brazilian Women

2001 ◽  
Vol 75 (13) ◽  
pp. 6242-6244 ◽  
Author(s):  
Steven S. Witkin ◽  
Iara M. Linhares ◽  
Stefan Gerber ◽  
Marie E. Caetano ◽  
Alusio C. Segurado
Keyword(s):  
Human Immunodeficiency Virus ◽  
Receptor Antagonist ◽  
Antiretroviral Treatment ◽  
Interleukin 1 ◽  
Hiv Rna ◽  
Interleukin 1 Receptor Antagonist ◽  
Immunodeficiency Virus ◽  
Circulating Levels ◽  
Hiv Seropositive

ABSTRACT Interleukin-1 receptor antagonist (IL-1ra) gene polymorphisms in 83 human immunodeficiency virus (HIV)-seropositive women were evaluated. Fourteen of the subjects (16.9%) were homozygous for IL-1ra allele 2 (IL-1RN*2). These women had a lower median level of HIV RNA than did women homozygous for allele 1 (IL-1RN*1) (P = 0.01) or heterozygous for both alleles (P = 0.04). Among 46 subjects not receiving antiretroviral treatment, HIV levels were also reduced in IL-1RN*2 homozygous individuals (P< 0.05). There was no relation between IL-1ra alleles and CD4 levels.

scholarly journals Mice transgenic for intracellular interleukin-1 receptor antagonist type 1 are protected from collagen-induced arthritis

2003 ◽  
Vol 33 (2) ◽  
pp. 434-440 ◽  
Author(s):  
Gaby Palmer ◽  
Dominique Talabot-Ayer ◽  
Ildiko Szalay-Quinodoz ◽  
Michel Maret ◽  
William P. Arend ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Collagen Induced Arthritis ◽  
Interleukin 1 Receptor Antagonist

scholarly journals The Systemic Immune Network in Recent Onset Type 1 Diabetes: Central Role of Interleukin-1 Receptor Antagonist (DIATOR Trial)

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e72440 ◽  
Author(s):  
Hubert Kolb ◽  
Kathrin Lückemeyer ◽  
Tim Heise ◽  
Christian Herder ◽  
Nanette C. Schloot ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Immune Network ◽  
Recent Onset ◽  
Onset Type ◽  
Interleukin 1 Receptor Antagonist
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