In Vitro Evaluation of Occlusal Caries Detection Methods in Primary and Permanent Teeth: A Comparison of CarieScan PRO, DIAGNOdent Pen, and DIAGNOcam Methods

Aim: This in vitro study was aimed to investigate the performance of the new caries detection tools on the incipient occlusal caries. Study design: In our study, 100 permanent molar teeth, which were considered to have incipient, enamel caries (D1 and D2 threshold values) according to ICDAS II score. After the visual examination, caries measurements have been applied to all teeth by using DIAGNOdent pen (DP), CarieScan PRO (CP) and SoproLife camera (SC). In addition, in vitro examinations were repeated 2 weeks later. After sectioning and evaluation in stereomicroscope, the lesion depth was determined with histological criteria that are accepted for the gold standard for this research. Sensitivity, specificity, accuracy and area under the ROC curve were calculated at D1 and D2 thresholds. The intra-examiners' reproducibility were analysed using Cohen's kappa statistics and intraclass correlation coefficient (ICC). Results: Intra-examiner repeatability values varied from 0.94 to 0.99 and kappa values ranged from 0.90 to 0.99. While the highest sensitivity and specificity value showed for SC at D1 and D2 thresholds, CP presented the lowest values. The area under ROC curves (Az) varied from 0.70 to 0.99. ICDAS II showed the highest area under ROC curves (Az). Conclusions: ICDAS II, visual diagnostic method by itself is considered to sufficient in order to diagnose incipient occlusal caries. SC may be used as an alternative method for the ICDAS II, since its advantages by displaying caries lesion on the computer monitor, follow-up and motivation of the patients provided.

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Study of validity of autofluorescence-based incipient occlusal caries detection in vitro compared to DIAGNOdent pen

Laser Physics ◽

10.1134/s1054660x12030310 ◽

2012 ◽

Vol 22 (3) ◽

pp. 614-619 ◽

Cited By ~ 5

Author(s):

H. H. Zhu ◽

Q. G. Chen ◽

B. Lin ◽

H. Chen

Keyword(s):

Caries Detection ◽

Occlusal Caries ◽

Occlusal Caries Detection ◽

Diagnodent Pen

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Comparative In Vitro Validation of VistaProof and DIAGNOdent Pen for Occlusal Caries Detection in Permanent Teeth

Operative Dentistry ◽

10.2341/10-326-l ◽

2012 ◽

Vol 37 (3) ◽

pp. 234-245 ◽

Cited By ~ 24

Author(s):

K Seremidi ◽

P Lagouvardos ◽

K Kavvadia

Keyword(s):

Clinical Relevance ◽

Laser Light ◽

Caries Detection ◽

Permanent Teeth ◽

Visual Methods ◽

Occlusal Caries ◽

Caries Diagnosis ◽

Diagnodent Pen ◽

Light Fluorescence

Clinical Relevance Laser/light fluorescence devices were highly reliable for occlusal caries diagnosis in permanent teeth but not superior in accuracy to visual methods.

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Sensitivity and Specificity of Different Diagnostic Methods in Occlusal Caries Detection of Permanent Teeth among Paediatric Patients

Archives of Orofacial Sciences ◽

10.21315/aos2021.16.2.3 ◽

2021 ◽

Vol 16 (2) ◽

pp. 113-126

Author(s):

Ilham Wan Mokhtar ◽

Annapurny Venkiteswaran ◽

Mohd Yusmiaidil Putera Mohd Yusof

Keyword(s):

Sensitivity And Specificity ◽

Near Infrared ◽

Visual Detection ◽

Diagnostic Methods ◽

Infrared Light ◽

Caries Detection ◽

Permanent Teeth ◽

Occlusal Caries ◽

Occlusal Caries Detection ◽

Occlusal Surfaces

Dental caries is a commonly progressive disease that proceeds through various degrees of severity that a dentist can detect. The aims of the in vivo study were to assess the accuracy of the individual model (near-infrared light transillumination [NILT] device, visual and radiographic examinations) in detecting occlusal caries, and to evaluate the performance of visual and NILT device combination for occlusal caries detection in deciding the treatment options. Fifty-two non-cavitated occlusal surfaces from 16 patients were assessed with three different diagnostic devices in random order. Identified lesions were prepared and validated. Logistic regression analysis was performed for each method. The sensitivity and specificity values for each method and the combined models were statistically measured using RStudio version 0.97.551. At the enamel level, visual detection was the most sensitive method (0.88), while NILT was the most specific (0.93). NILT scored the highest for sensitivity (0.93) at the dentine level and visual detection scored the highest for specificity (0.88). Visual detection + NILT model was significantly better (p = 0.04) compared to visual detection or NILT alone (df = 1). The visual-NILT combination is a superior model in detecting occlusal caries on permanent teeth. The model provided surplus value in caries detection hence improving the treatment decision-making in occlusal surfaces.

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Automated Caries Detection using a 3D Intraoral Scanner. An in Vivo Validation Study

10.21203/rs.3.rs-590542/v1 ◽

2021 ◽

Author(s):

Stavroula Michou ◽

Mathias S. Lambach ◽

Panagiotis Ntovas ◽

Ana R. Benetti ◽

Azam Bakhshandeh ◽

...

Keyword(s):

Diagnostic Performance ◽

Periodontal Diseases ◽

Caries Detection ◽

Oral Diseases ◽

Visual Examination ◽

Occlusal Caries ◽

Tooth Color ◽

Occlusal Caries Detection

Abstract The use of 3D intraoral scanners (IOS) and software that can support automated detection and objective monitoring of oral diseases such as caries, tooth wear or periodontal diseases is increasingly receiving attention from researchers and industry. This study clinically validates an automated caries scoring system for occlusal caries detection and classification, previously developed for an IOS system featuring fluorescence (TRIOS 4, 3Shape TRIOS A/S, Denmark). Four algorithms (ALG1, ALG2, ALG3, ALG4) are assessed for the IOS; the first three are based only on fluorescence information, while ALG4 also takes into account the tooth color information. The diagnostic performance of these automated algorithms is compared with the diagnostic performance of the clinical visual examination, while histological assessment is used as reference. Additionally, possible differences between in vitro and in vivo diagnostic performance of the IOS system are investigated. The algorithms show comparable in vivo diagnostic performance to the visual examination. Only minor differences between their in vitro and in vivo diagnostic performance are noted. This novel IOS system exhibits encouraging performance for clinical application on occlusal caries detection and classification. Different approaches can be investigated for possible optimization of the system.

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Validation of micro-computed tomography for occlusal caries detection: an in vitro study

Brazilian Oral Research ◽

10.1590/1807-3107bor-2015.vol29.0132 ◽

2015 ◽

Vol 29 (1) ◽

Cited By ~ 17

Author(s):

Gökhan ÖZKAN ◽

Aydan KANLI ◽

Nurdan Meserret BAŞEREN ◽

Umut ARSLAN ◽

İlkan TATAR

Keyword(s):

Computed Tomography ◽

In Vitro Study ◽

Vitro Study ◽

Caries Detection ◽

Micro Computed Tomography ◽

Occlusal Caries ◽

Occlusal Caries Detection

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In vitro Detection of Occlusal Caries on Permanent Teeth by a Visual, Light-Induced Fluorescence and Photothermal Radiometry and Modulated Luminescence Methods

Caries Research ◽

10.1159/000437214 ◽

2015 ◽

Vol 49 (5) ◽

pp. 523-530 ◽

Cited By ~ 12

Author(s):

Mahmoud Jallad ◽

Domenick Zero ◽

George Eckert ◽

Andrea Ferreira Zandona

Keyword(s):

Preventive Intervention ◽

Early Stage ◽

Characteristic Curve ◽

Intraclass Correlation ◽

Assessment System ◽

Photothermal Radiometry ◽

Caries Detection ◽

Permanent Teeth ◽

Occlusal Caries

Background: The paradigm shift towards the nonsurgical management of dental caries relies on the early detection of the disease. Detection of caries at an early stage is of unequivocal importance for early preventive intervention. Objective: The aim of this in vitro study is to evaluate the performance of a visual examination using the International Caries Detection and Assessment System (ICDAS) criteria, two quantitative light-induced fluorescence (QLF) systems - Inspektor™ Pro and QLF-D Biluminator™ 2 (Inspektor Research Systems B.V., Amsterdam, The Netherlands) - and a photothermal radiometry and modulated luminescence, The Canary System® (Quantum Dental Technologies, Toronto, Ont., Canada) on the detection of primary occlusal caries on permanent teeth. Methods: A total of 60 teeth with occlusal surface sites ranging from sound to noncavitated lesions (ICDAS 0-4) were assessed with each detection method twice in a random order. Histological validation was used to compare methods for sensitivity, specificity, percent correct, and the area under the receiver operating characteristic curve (AUC), at standard and optimum sound thresholds. Interexaminer agreement and intraexaminer repeatability were measured using intraclass correlation coefficients. Results: Interexaminer agreement ranged between 0.48 (The Canary System®) and 0.96 (QLF-D Biluminator™ 2). Intraexaminer repeatability ranges were 0.33-0.63 (The Canary System®) and 0.96-0.99 (QLF-D Biluminator™ 2). The sensitivity range was 0.75-0.96 while that of specificity was 0.43-0.89. The AUC were 0.79 (The Canary System®), 0.87 (ICDAS), 0.90 (Inspektor™ Pro), and 0.94 (QLF-D Biluminator™ 2). Conclusion: ICDAS had the best combination of sensitivity and specificity followed by QLF-D Biluminator™ 2 at optimum threshold.

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Detection of Non-Cavitated Occlusal Caries with Impedance Spectroscopy and Laser Fluorescence: an In Vitro Study

The Open Dentistry Journal ◽

10.2174/1874210601408010028 ◽

2014 ◽

Vol 8 (1) ◽

pp. 28-32 ◽

Cited By ~ 7

Author(s):

Diana Mortensen ◽

Katrine Dannemand ◽

Svante Twetman ◽

Mette Kirstine Keller

Keyword(s):

Impedance Spectroscopy ◽

Laser Fluorescence ◽

In Vivo Studies ◽

Permanent Teeth ◽

Occlusal Caries ◽

Posterior Teeth ◽

Diagnodent Pen ◽

Occlusal Surfaces ◽

Caries Lesions

Objective: To evaluate the performance of an impedance spectroscopy technology for detecting non-cavitated occlusal caries lesions in permanent teeth in vitro. The method was compared with a commonly used laser fluorescence device and validated against histology. Material and Methodology: A non-cavitated sample of 100 extracted posterior teeth was randomly selected and assessed for caries on enamel and dentin level with aid of CarioScan PRO (ACIS) and DIAGNOdent pen (LF pen) by three examiners. After the measurements, the extension of the lesion was histologically determined as gold standard. Sensitivity, specificity, accuracy and receiver-operating curves were calculated. Intra- and inter-examiner reproducibility was expressed by intra class correlation coefficients. Results: The histological caries prevalence was 99% and 41% exhibited dentin caries. The ACIS technique displayed high specificities but almost negligible sensitivities at readings >50. A similar pattern was noted for the LF pen at readings >30. The intra- and inter-examiner reproducibility varied between 0.47 and 0.98 and the values were generally lower for the ACIS technique than for the LF pen. The inter-examiner agreement reached excellent levels with both methods. Conclusions: In vitro, the ACIS technique showed a low ability to disclose occlusal caries lesions in the enamel and/or dentin of non-cavitated permanent molars. However, further in vivo studies of permanent occlusal surfaces are needed to mirror the clinical situation.

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