scholarly journals Effects of Biologic Scaffolds on Human Stem Cells and Implications for CNS Tissue Engineering

2014 ◽  
Vol 20 (1-2) ◽  
pp. 313-323 ◽  
Author(s):  
Peter M. Crapo ◽  
Stephen Tottey ◽  
Peter F. Slivka ◽  
Stephen F. Badylak
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Human Stem Cells

scholarly journals Stem Cells: A Gold Mine in Dental Research and Tissue Engineering

2019 ◽  
Vol 2 (2) ◽  
pp. 41-44
Author(s):  
Hashmi Rahat ◽  
◽  
Ahmad Fahim ◽  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Developmental Biology ◽  
Nervous System ◽  
Well Being ◽  
Gold Mine ◽  
Scientific Journals ◽  
Health Issues ◽  
Human Stem Cells ◽  
Health And Well Being

The explosion of articles not only in scientific journals, but also in the print media and continuous TV debates, one could easily say the term “stem cells” has become synonym to the word “cure”. The extraordinary advances in the prevention, diagnosis, and treatment of human diseases, such as oral health issues, cancer, heart disease, diabetes and diseases of the central and peripheral nervous system, such as Parkinson's disease and Alzheimer's disease, continues to deprive people of health and well-being. Tremendous effort and exceptional research in human developmental biology has led to the identification and discovery of human stem cells.

scholarly journals Bioprinting with human stem cells-laden alginate-gelatin bioink and bioactive glass for tissue engineering

2019 ◽  
Vol 5 (2.2) ◽  
pp. 3 ◽  
Author(s):  
Krishna C. R. Kolan ◽  
Julie A. Semon ◽  
Bradley Bromet ◽  
Delbert E. Day ◽  
Ming C. Leu
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Bioactive Glass ◽  
Three Dimensional ◽  
Cell Types ◽  
3D Models ◽  
Culture Conditions ◽  
3D Bioprinting ◽  
Human Stem Cells ◽  
Tissue Repair And Regeneration

Three-dimensional (3D) bioprinting technologies have shown great potential in the fabrication of 3D models for different human tissues. Stem cells are an attractive cell source in tissue engineering as they can be directed by material and environmental cues to differentiate into multiple cell types for tissue repair and regeneration. In this study, we investigate the viability of human adipose-derived mesenchymal stem cells (ASCs) in alginate-gelatin (Alg-Gel) hydrogel bioprinted with or without bioactive glass. Highly angiogenic borate bioactive glass (13-93B3) in 50 wt% is added to polycaprolactone (PCL) to fabricate scaffolds using a solvent-based extrusion 3D bioprinting technique. The fabricated scaffolds with 12 × 12 × 1 mm3 in overall dimensions are physically characterized, and the glass dissolution from PCL/glass composite over a period of 28 days is studied. Alg-Gel composite hydrogel is used as a bioink to suspend ASCs, and scaffolds are then bioprinted in different configurations: Bioink only, PCL+bioink, and PCL/glass+bioink, to investigate ASC viability. The results indicate the feasibility of the solvent-based bioprinting process to fabricate 3D cellularized scaffolds with more than 80% viability on day 0. The decrease in viability after 7 days due to glass concentration and static culture conditions is discussed. The feasibility of modifying Alg-Gel with 13-93B3 glass for bioprinting is also investigated, and the results are discussed.

scholarly journals Bone tissue engineering with human stem cells

2010 ◽  
Vol 1 (2) ◽  
pp. 10 ◽  
Author(s):  
Darja Marot ◽  
Miomir Knezevic ◽  
Gordana Novakovic
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Human Stem Cells

scholarly journals Hydrogel fibers encapsulating human stem cells in an injectable calcium phosphate scaffold for bone tissue engineering

2016 ◽  
Vol 11 (6) ◽  
pp. 065008 ◽  
Author(s):  
Lin Wang ◽  
Ping Wang ◽  
Michael D Weir ◽  
Mark A Reynolds ◽  
Liang Zhao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Calcium Phosphate ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Human Stem Cells

Human Stem Cells and Articular Cartilage Tissue Engineering

2012 ◽  
Vol 13 (15) ◽  
pp. 2682-2691 ◽  
Author(s):  
J-F. Stoltz ◽  
C. Huselstein ◽  
J. Schiavi ◽  
Y.Y. Li ◽  
D. Bensoussan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Articular Cartilage ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Human Stem Cells
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