A rigid local system with monodromy group the big Conway group $2.\mathsf {Co}_1$ and two others with monodromy group the Suzuki group $6.{{Suz}}$

AbstractOestradiol, an important hormone in follicular development and endometrial receptivity, is closely related to clinical outcomes of fresh in vitro fertilization-embryo transfer (IVF-ET) cycles. A supraphysiologic E2 level is inevitable during controlled ovarian hyper-stimulation (COH), and its effect on the outcome of IVF-ET is controversial. The aim of this retrospective study is to evaluate the association between elevated serum oestradiol (E2) levels on the day of human chorionic gonadotrophin (hCG) administration and neonatal birthweight after IVF-ET cycles. The data of 3659 infertile patients with fresh IVF-ET cycles were analysed retrospectively between August 2009 and February 2017 in First Hospital of Zhengzhou University. Patients were categorized by serum E2 levels on the day of hCG administration into six groups: group 1 (serum E2 levels ≤ 1000 pg/mL, n = 230), group 2 (serum E2 levels between 1001 and 2000 pg/mL, n = 524), group 3 (serum E2 levels between 2001 and 3000 pg/mL, n = 783), group 4 (serum E2 levels between 3001 and 4000 pg/mL, n = 721), group 5 (serum E2 levels between 4001 and 5000 pg/mL, n = 548 ), and group 6 (serum E2 levels > 5000 pg/mL, n = 852). Univariate linear regression was used to evaluate the independent correlation between each factor and outcome index. Multiple logistic regression was used to adjust for confounding factors. The LBW rates were as follows: 3.0% (group 1), 2.9% (group 2), 1.9% (group 3), 2.9% (group 4), 2.9% (group 5), and 2.0% (group 6) (P = 0.629), respectively. There were no statistically significant differences in the incidences of neonatal LBW among the six groups. We did not detect an association between peak serum E2 level during ovarian stimulation and neonatal birthweight after IVF-ET. The results of this retrospective cohort study showed that serum E2 peak levels during ovarian stimulation were not associated with birth weight during IVF cycles. In addition, no association was found between higher E2 levels and increased LBW risk. Our observations suggest that the hyper-oestrogenic milieu during COS does not seem to have adverse effects on the birthweight of offspring after IVF. Although this study provides some reference, the obstetric-related factors were not included due to historical reasons. The impact of the high estrogen environment during COS on the birth weight of IVF offspring still needs future research.

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Melatonin attenuates ovarian ischemia reperfusion injury in rats by decreasing oxidative stress index and peroxynitrite

TURKISH JOURNAL OF MEDICAL SCIENCES ◽

10.3906/sag-2004-135 ◽

2020 ◽

Vol 50 (6) ◽

pp. 1513-1522

Author(s):

Şenol KALYONCU ◽

Bülent YILMAZ ◽

Mustafa DEMİR ◽

Meltem TUNCER ◽

Zehra BOZDAĞ ◽

...

Keyword(s):

Oxidative Stress ◽

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Stress Index ◽

Oxidative Stress Index ◽

Group 6 ◽

Group 3 ◽

Group 2 ◽

Group 1

Background/aim: To evaluate the protective effect of melatonin on ovarian ischemia reperfusion injury in a rat model. Materials and methods: Forty-eight rats were separated equally into 6 groups. Group 1: sham; Group 2: surgical control with 3-h bilateral ovarian torsion and detorsion; Group 3: intraperitoneal 5% ethanol (1 mL) just after detorsion (as melatonin was dissolved in ethanol); Group 4: 10 mg/kg intraperitoneal melatonin 30 min before 3-h torsion; Group 5:10 mg/kg intraperitoneal melatonin just after detorsion; Group 6:10 mg/kg intraperitoneal melatonin 30 min before torsion and just after detorsion. Both ovaries and blood samples were obtained 7 days after detorsion for histopathological and biochemical analysis.Results: In Group 1, serum levels of total oxidant status (TOS) (μmol H2O2 equivalent/g wet tissue)were significantly lower than in Group2 (P = 0.0023), while tissue TOS levels were lower than in Group 3 (P = 0.0030). Similarly, serum and tissue levels of peroxynitrite in Group 6were significantly lower than those ofGroup 2 (P = 0.0023 and P = 0.040, respectively). Moreover, serum oxidative stress index (OSI) (arbitrary unit) levels were significantly increased in Group 2 when compared to groups 1 and 6 (P = 0.0023 and P= 0.0016, respectively) and in Group 3 with respect to groups 1, 4, 5, and 6 (P = 0.0023, P = 0.0026, P = 0.0008, and P = 0.0011, respectively). Furthermore, there was a significant decrease in histopathological scores including follicular degeneration, vascular congestion, hemorrhage, and inflammation in the melatonin and sham groups in comparison with control groups. Additionally, primordial follicle count was significantly higher in Group 6 than in Group 2 (P = 0.0002).Conclusion: Melatonin attenuates ischemia reperfusion damage in a rat torsion/detorsion model by improving histopathological and biochemical findings including OSI and peroxynitrite.

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EFFECT OF TREATMENT WITH STREPTOKINASE AND HEPARIN ON FIBRINOGEN, FIBRIN AND RELATED PROTEINS IN ACUIE MYOCARDIAL INFARCTION (/ME) PATIENTS

10.1055/s-0038-1644895 ◽

1987 ◽

Author(s):

V Vila ◽

E Reganon ◽

J Aznar ◽

V Lacueva ◽

M Ruano

Keyword(s):

Degradation Products ◽

Heparin Therapy ◽

Heparin Group ◽

Normal Value ◽

Group 4 ◽

Group 6 ◽

Group 3 ◽

Group 5 ◽

Group 2 ◽

Group 1

The properties of fibrinogen and fibrin, the levels of fibrincpeptide A (FPA) and fibrin(ogen) degradation products (FDP) were studied in 34 patients with AMI who were undergoing thrombolytic and heparin therapy. They were classified into 6 groups accordingto their stage of treatment: group 1, before intravenous administration of 800.000 U streptokinase over 30 min; group 2, after a<Mnistraticn of SK but before adninistraticn of heparin; group 3, during 24 h ofthe 5 ng/h heparin continuous infusion; group 4, during 48-72 h of the 16.6 ng/h heparin continuous infhsion; group 5, after 1 week of administration of SK and with a bolus inyection of 50 rg heparin every 4 h; group 6, patients who were undergoing only heparin treatment. The Fg 1/ Fg II ratio varies during treatment with SK and heparin. In group 1 a sligjnt increase (2.5) is observed. Group 2 shows a significantdecrease (0.6) as a result of fibrinolysis. In group3 the ratio reaches normal value (1.8) while in the fourth group it is twice the normal value (4). The value for group 5 is nearly normal (2.1), and in group 6 it reaches values similar to those obtained in group 4, which implies that the rise in the Fgl/Fgll ratio is not a result of fibrinolytic treatment. TheFPA level shows and increase in patients with AMI (group 1,126 ng/ml). When SK treatment is applied (group 2), FPA decreases to 52 ng/ml. Later treatment with heparin (group-3, 82; group-4, 44 and group-5, 81ng/ml) does not neutralize thrcmbinic activity. Patients treated only with heparin (group 6) show an FPAvalue of 19 ng/ml, which is lower than in the other groups. All of this indicates that thrombin is activated after fibrinolytic treatment. FDP values show asignificant increase in the six groups (1, 53; 2, 430; 3, 128; 4, 270; 5, 139 and 6, 141 ug/ml), which indicates that during treatment with heparin the fibrinolytic activity persists. he formation of highly cross-linked fibrin is altered in groups 1,2,3 and 4,as a consequence of circulating FDP effect and fibrincgeno- lysis.The permeability of the fibrin clotdecreases in groups 1 (0.42), 2 (1.3), 4 (1.1) and 5(0.5 ml/s/ng) and increases in group 2 (23.2 ml/s/nig) with respect to the normal plasma value (3.2 ml/s/nrg). The decrease in permeability must be related to the existence of hypercoagulability resistant to heparinization. FPA values, tine Fgl/Fgll ratio, andfibrin permeability can be used to evaluate the degree of thrcmbin activity during thrombolytic treatmentinAMI.

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Estudo de fraturas nos taludes de corte, em rocha vulcânica, ao longo da BR 158, Santa Maria, RS

Ciência e Natura ◽

10.5902/2179460x27022 ◽

1999 ◽

Vol 21 (21) ◽

pp. 97

Author(s):

Andrea V. Nummer ◽

Luis Eduardo S. Robaina ◽

Marcos Geovane Berger

Keyword(s):

Conditioning Factors ◽

Weathering Processes ◽

Group 4 ◽

Group 6 ◽

Group 3 ◽

Group 5 ◽

Group 2 ◽

Road Data ◽

Santa Maria ◽

Group 1

Weathering processes and jointing degree are the conditioning factors for rock falI.The fractured volcanic lithologies from Santa Maria, RS, Brazil, were studied along the BR 158 road. Data was gathered through the Scanline method from BRADY & BROWN (1985) and analyzed by vector statistics.Six main jointing groups were defined, associated to rock cooling and shrinking. Main attitudes are: Group 1: 348;83; Group 2: 174;82; Group 3: 85;76; Group 4: 265;75; Group 5: 300;42 and Group 6: 121 ;53.

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Anticaries Potential of Commercial Dentifrices as Determined by Fluoridation and Remineralization Efficiency

The Journal of Contemporary Dental Practice ◽

10.5005/jcdp-8-7-1 ◽

2007 ◽

Vol 8 (7) ◽

pp. 1-10 ◽

Cited By ~ 12

Author(s):

Elias Casals ◽

Tchilalo Boukpessi ◽

Christina M. McQueen ◽

Sandy L. Eversole ◽

Robert V. Faller

Keyword(s):

Surface Hardness ◽

Reference Standard ◽

Surface Microhardness ◽

Fluoride Uptake ◽

Human Enamel ◽

Demineralized Enamel ◽

Group 6 ◽

Group 3 ◽

Group 2

Abstract Aim The aim of this in vitro study was to investigate fluoride uptake in human enamel after use of commercially available toothpastes containing different fluoride compounds, or combinations of fluoride actives formulated into a single product, as a means of determining the efficiency of each formula for delivering caries preventing fluoride to demineralized (caries active) enamel. Methods and Materials Four test dentifrices and two controls were assessed and placed in groups as follows: Group 1: Lacer® (Spain); Group 2: Positive control-USP Reference Standard 1100 ppm F; Group 3: Fluocaril® Bi-Fluoré 250 (France); Group 4: Colgate Fluor Active (Denmark); Group 5: Elmex® (France); and Group 6: A placebo (formulated the same as the USP Reference Standard toothpaste with the exception that it contained < 1 ppm F). Cores 3 mm in diameter were removed from erupted human enamel specimens (extracted by local oral surgeons for orthodontic reasons) and stored in 1% Thymol solution prior to use. They were ground and polished to remove the natural fluoride rich enamel layer, then exposed to a demineralization solution, and assessed for surface microhardness to enable randomization for use in the study. Each group of five specimens underwent a daily pH cycling procedure that involved exposure to pooled human saliva (refreshed three times daily). The groups were then exposed to dentifrice slurries four times daily for one minute per exposure and to a demineralization solution for three hours. The cycling procedure was repeated for five days. Specimens were again analyzed for surface microhardness and fluoride uptake upon completion of five days of treatment. Results Average surface hardness: Groups 2 and 3 showed a statistically significant greater (p<0.05) change indicating greater remineralization compared to all other groups. The average change was 23.45 for Group 2 and 22.65 for Group 3. All other groups had changes ranging from 4.25-8.62. No other statistically significant differences were observed between groups. Fluoride uptake results: Groups 2 and 3 showed statistically significantly greater fluoride uptake versus all other groups (p <0.05). Groups 1 and 5 were significantly different from Group 6. No other statistically significant differences were observed for either analysis. Conclusions Of the marketed products included in the study, the Fluocaril® Bi-Fluoré 250 product formulation provided both the highest level of fluoride uptake and mineralization to the demineralized enamel. The clinical significance of these in vitro results is the confirmation Fluocaril® Bi-Fluoré 250 is effective at remineralizing enamel caries lesions. Citation Casals E, Boukpessi T, McQueen CM, Eversole SL, Faller RV. Anticaries Potential of Commercial Dentifrices as Determined by Fluoridation and Remineralization Efficiency. J Contemp Dent Pract 2007 November; (8)7:001-010.

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Dentin Bond Strength of Composites with Self-etching Adhesives Using LED Curing Lights

The Journal of Contemporary Dental Practice ◽

10.5005/jcdp-8-5-34 ◽

2007 ◽

Vol 8 (5) ◽

pp. 34-42 ◽

Cited By ~ 6

Author(s):

Yonca Korkmaz ◽

Nuray Attar

Keyword(s):

Bond Strength ◽

Testing Machine ◽

Significance Level ◽

Group 4 ◽

Group 6 ◽

Group 3 ◽

Curing Light ◽

Group 5 ◽

Group 2 ◽

Self Etch

Abstract Aim The purpose of this study was to investigate the effect of light-emitting diode (LED) light curing units (LCUs) compared with halogen LCUs on the shear bond strength (SBS) of one nanofill composite (Filtek Supreme) and one microhibrid composite (Artemis) with self-etch adhesives. Methods and Materials The buccal surfaces of 60 non-carious extracted human molars were flattened to expose dentin and, subsequently, polished for 60 seconds with 600-grit wet silicon carbide abrasive paper. Specimens were assigned into six groups (n=10) according to composite material, self-etch adhesive, and curing light used as follows: Group 1: Adper Prompt L-Pop (AP) and Filtek Supreme (FS) using an Elipar Free Light (EFL); Group 2: AP and FS using an Elipar Free Light 2 (EFL2); Group 3: AP and FS using a Hilux Expert (HE) light, Group 4: AdheSE (AS)+Artemis (AR) using an EFL; Group 5: AS+AR using an EFL2; and Group 6: AS+AR using a HE light. The specimens were thermocycled for 500 cycles (5°C–55°C) and then loaded to failure in a Zwick universal testing machine at a crosshead speed of 5 mm/minute. SBS values were calculated as megapascals (MPa) and statistically analyzed using the one-way analysis of variance (ANOVA) test at a significance level of 0.05. Results Mean SBS (± standard deviations) values were as follows: Group1: 15.99±5.18; Group 2: 18.76±6.71; Group 3: 17.70±5.04; Group 4: 16.93±3.99; Group 5: 18.01±5.19, and Group 6: 17.46±5.40. There were no statistically significant differences for SBS to dentin among the groups tested. Conclusion The LED curing lights used in the study seem to be comparable with the halogen curing light for nanofill and microhybrid composites used in conjunction with self-etching systems in dentin. The EFL2 reduces curing time, which can be considered as an advantage. Citation Korkmaz Y, Attar N. Dentin Bond Strength of Composites with Self-etching Adhesives Using LED Curing Lights. J Contemp Dent Pract 2007 July;(8)5:034-042.

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A differential equation with monodromy group 2.J2

Journal of Algebra ◽

10.1016/j.jalgebra.2016.03.023 ◽

2016 ◽

Vol 458 ◽

pp. 249-264

Author(s):

Stefan Reiter

Keyword(s):

Differential Equation ◽

Monodromy Group ◽

Group 2

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Anti-hypercholesterolemic effect of Zingiber montanum extract

F1000Research ◽

10.12688/f1000research.16417.2 ◽

2019 ◽

Vol 7 ◽

pp. 1798

Author(s):

Swandari Paramita ◽

Meiliati Aminyoto ◽

Sjarif Ismail ◽

Enos Tangke Arung

Keyword(s):

Total Cholesterol ◽

Plant Extracts ◽

High Fat Diet ◽

High Cholesterol ◽

High Fat ◽

Group 4 ◽

Cholesterol Levels ◽

Group 6 ◽

Diet Control ◽

Group 2

Background: High cholesterol levels (hypercholesterolemia) has been recognized to cause various disease, most notably the cardiovascular disease. Unfortunately, most anti-hypercholesterolemic drugs deliver several side effects for patients, by which medicinal plants have begun to attract attention for treating hypercholesterolemia. Among others, Zingiber montanum (J.König) Link ex A.Dietr. has traditionally been taken for treating health problems caused by high cholesterol levels. Hence, this work aimed at investigating anti-hypercholesterolemic effects offered by the plant. Methods: This study was conducted on 30 male Wistar rats. During experiments, the subjects were divided into 6 groups (n=5), i.e. no treatment (Group 1, control); high-fat diet (Group 2, control); high-fat diet with simvastatin (Group 3); high-fat diet with plant extracts (Group 4-6 with 100, 200, and 400 mg/kg BW, respectively). After 4 weeks of treatments, blood samples were collected from each group. Then, plasma concentrations of triglycerides, total cholesterol, high density lipoproteins (HDL), and low density lipoproteins (LDL) were measured. Results: There were significant differences in total cholesterol (p=0.000), LDL (p=0.000) and triglycerides (p=0.001) for Groups 4-6 (high-fat diet treated with different plant extract doses) in comparison with Group 2 (high-fat diet, control). Meanwhile, there were no significant differences in HDL levels (p=0.830) between Group 2 (high-fat diet, control) and other groups. The results also showed significant differences in total cholesterol and LDL for subjects treated with plant extracts (Group 4, 100 mg/kg BW, p=0.000; Group 5, 200 mg/kg BW, p=0.000; Group 6, 400 mg/kg BW, p=0.000) compared to Group 2 (high-fat diet, control). Then, treatments with 400 mg/kg BW (Group 6) discovered significant reductions in total cholesterol, LDL, and triglycerides (p=0.030). Conclusion: Therefore, Z. montanum has been discovered to deliver anti-hypercholesterolemic effects to experimental subjects, making it potential to act as a natural source of anti-hypercholesterolemic agents.

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Effect of Aqueous Extract of Tribulus terrestris orally administration on some Biochemical Parameters in Castrated Male Rabbits

The Iraqi Journal of Veterinary Medicine ◽

10.30539/iraqijvm.v36i2.499 ◽

2012 ◽

Vol 36 (2) ◽

pp. 217-221

Author(s):

Abeer Uthman Moosa

Keyword(s):

Aqueous Extract ◽

Biochemical Parameters ◽

Iron Concentration ◽

Iron Phosphate ◽

Tribulus Terrestris ◽

Biochemical Tests ◽

Group 6 ◽

Group 5 ◽

Group 2 ◽

Group 1

The present study is aimed to investigate the influence of an aqueous extract of Tribulus terrestris on some biochemical parameters namely, alkaline phosphatase (ALP), Iron, phosphate (PO4), sodium (Na+), potassium (K+), aldosterone, and cortico steroid in unilateral and bilateral castrated male rabbits. Thirty mature male rabbits which are divided randomly in to six groups. group 1: is control, group2: orally administrated 150 mg / kg / day of an aqueous extract of T. terrestris, group3: is bilateral castrated rabbits received D. W., group4: is bilateral castrated rabbits received (150 mg / kg / day) of the extract, group 5: unilateral castrated rabbits received D. W., group 6 is unilateral castrated rabbits received 150 mg / kg / day of the extract, all doses were given orally every day for 30 days. At the end of the experiment, sera were collected and biochemical tests measured. The results showed a significant (P<0.05) increased in ALP level in group 2 and in PO4 level in group 5 in comparison with group1, while PO4 level tended to be decreased significantly (P<0.05) in group 6 when it compared with group 5. The results also showed a significant(P<0.05) increased in (K+) and (Na+) in group 2 and group 6 in comparison with group1 while there was a significant(P<0.05) decreased in (K+) and (Na+) in group 4 when it compared with group 2. In addition there was a significant (P<0.05) increased in aldosterone concentration in group 6 compared with group 1 and group 2. While there was a significant decreased in cortico steroid concentration in group 3 , 5 and 2 compared with group 1 but the cortico steroid showed a significant (P<0.05) increased in group 6 compared with group 1. There were no significant differences between groups concerning the iron concentration.

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