scholarly journals Short-term serum deprivation causes no significant mitochondrial DNA mutation in vascular smooth muscle cells revealed by a new next generation sequencing technology

2016 ◽  
Vol 48 (9) ◽  
pp. 862-864 ◽  
Author(s):  
Xiangqi Li ◽  
Lianyong Liu ◽  
Qian Xi ◽  
Xuemei Zhao ◽  
Mingshuang Fang ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Smooth Muscle ◽  
Next Generation Sequencing ◽  
Vascular Smooth Muscle Cells ◽  
Sequencing Technology ◽  
Short Term ◽  
Mitochondrial Dna Mutation ◽  
Next Generation Sequencing Technology ◽  
Dna Mutation ◽  
Generation Sequencing

A novel ATP8 gene mutation in an infant with tetralogy of Fallot

2013 ◽  
Vol 24 (3) ◽  
pp. 531-533 ◽  
Author(s):  
Turkan Tansel ◽  
Ferda Paçal ◽  
Duran Ustek
Keyword(s):  
Mitochondrial Dna ◽  
Next Generation Sequencing ◽  
Missense Mutation ◽  
Tetralogy Of Fallot ◽  
Gene Mutation ◽  
Mitochondrial Dna Mutation ◽  
Dna Mutation ◽  
Atp8 Gene ◽  
Generation Sequencing ◽  
Hereditary Optic Neuropathy

AbstractWe report the case of a novel mitochondrial DNA mutation in the MT-ATP8 gene in an infant with tetralogy of Fallot. Next-generation sequencing was applied to sequence whole mitochondrial DNA of the patient. A known Leber's hereditary optic neuropathy-associated mutation (G9804A), a heteroplasmic T7501C mutation (17%), and a novel C8481 T Pro > Leu missense mutation in the MT-ATP8 gene was identified.

Towards a clearer picture of somatic mitochondrial DNA mutation spectrums using next generation sequencing

Mitochondrion ◽  
2012 ◽  
Vol 12 (5) ◽  
pp. 566
Author(s):  
Siôn Williams ◽  
Alicia Pickrell ◽  
Lloye Dillon ◽  
Sandra Bacman ◽  
Deborah Mash ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Next Generation Sequencing ◽  
Next Generation ◽  
Mitochondrial Dna Mutation ◽  
Dna Mutation ◽  
Generation Sequencing

scholarly journals Identification of a Novel Papillomavirus Type (MfoiPV1) Associated with Acrochordon in a Stone Marten (Martes foina)

Pathogens ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 539
Author(s):  
Urška Kuhar ◽  
Diana Žele Vengušt ◽  
Urška Jamnikar-Ciglenečki ◽  
Gorazd Vengušt
Keyword(s):  
Next Generation Sequencing ◽  
Clinical Manifestation ◽  
Skin Tumor ◽  
Wild Animals ◽  
Stone Marten ◽  
Sequencing Technology ◽  
Martes Foina ◽  
Tumor Sample ◽  
Next Generation Sequencing Technology ◽  
Generation Sequencing

Papillomaviruses (PVs) are an extremely large group of viruses that cause skin and mucosal infections in humans and various domestic and wild animals. Nevertheless, there is limited knowledge about PVs in wildlife hosts, including mustelid species. This study describes a case in stone marten (Martes foina) with a clinical manifestation of skin tumor, which is rather atypical for infections with PVs. The result of the papillomavirus PCR performed on the skin tumor sample was positive, and the complete PV genome was determined in the studied sample using next-generation sequencing technology. The analysis of the PV genome revealed infection of the stone marten with a putative new PV type belonging to the Dyonupapillomavirus genus. The proposed new stone marten PV type was named MfoiPV1.

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