Kilograms Matter: Rational Analysis, Ecological Rationality, and Closed-Loop Modeling of Interactive Cognition and Behavior

2009 ◽  
pp. 267-284 ◽  
Author(s):  
Michael D. Byrne ◽  
Alex Kirlik ◽  
Chris S. Fick
Keyword(s):  
Closed Loop ◽  
Ecological Rationality ◽  
Loop Modeling ◽  
Rational Analysis ◽  
And Behavior

scholarly journals An Intracortical Implantable Brain-Computer Interface for Telemetric Real-Time Recording and Manipulation of Neuronal Circuits for Closed-Loop Intervention

2021 ◽  
Vol 15 ◽  
Author(s):  
Hamed Zaer ◽  
Ashlesha Deshmukh ◽  
Dariusz Orlowski ◽  
Wei Fan ◽  
Pierre-Hugues Prouvot ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Real Time ◽  
Neuronal Activity ◽  
Closed Loop ◽  
Neural Circuit ◽  
Radio Communication ◽  
Computer Interfaces ◽  
Cerebral Mri ◽  
High Bandwidth ◽  
And Behavior

Recording and manipulating neuronal ensemble activity is a key requirement in advanced neuromodulatory and behavior studies. Devices capable of both recording and manipulating neuronal activity brain-computer interfaces (BCIs) should ideally operate un-tethered and allow chronic longitudinal manipulations in the freely moving animal. In this study, we designed a new intracortical BCI feasible of telemetric recording and stimulating local gray and white matter of visual neural circuit after irradiation exposure. To increase the translational reliance, we put forward a Göttingen minipig model. The animal was stereotactically irradiated at the level of the visual cortex upon defining the target by a fused cerebral MRI and CT scan. A fully implantable neural telemetry system consisting of a 64 channel intracortical multielectrode array, a telemetry capsule, and an inductive rechargeable battery was then implanted into the visual cortex to record and manipulate local field potentials, and multi-unit activity. We achieved a 3-month stability of the functionality of the un-tethered BCI in terms of telemetric radio-communication, inductive battery charging, and device biocompatibility for 3 months. Finally, we could reliably record the local signature of sub- and suprathreshold neuronal activity in the visual cortex with high bandwidth without complications. The ability to wireless induction charging combined with the entirely implantable design, the rather high recording bandwidth, and the ability to record and stimulate simultaneously put forward a wireless BCI capable of long-term un-tethered real-time communication for causal preclinical circuit-based closed-loop interventions.

scholarly journals Open source modules for tracking animal behavior and closed-loop stimulation based on Open Ephys and Bonsai

2018 ◽  
Author(s):  
Alessio Paolo Buccino ◽  
Mikkel Elle Lepperød ◽  
Svenn-Arne Dragly ◽  
Philipp Häfliger ◽  
Marianne Fyhn ◽  
...  
Keyword(s):  
Open Source ◽  
Real Time ◽  
Closed Loop ◽  
Low Cost ◽  
Data Formats ◽  
Behavioral Tracking ◽  
Real Time Tracking ◽  
Set Up ◽  
And Behavior ◽  
Closed Loop Stimulation

AbstractObjectiveA major goal in systems neuroscience is to determine the causal relationship between neural activity and behavior. To this end, methods that combine monitoring neural activity, behavioral tracking, and targeted manipulation of neurons in closed-loop are powerful tools. However, commercial systems that allow these types of experiments are usually expensive and rely on non-standardized data formats and proprietary software which may hinder user-modifications for specific needs. In order to promote reproducibility and data-sharing in science, transparent software and standardized data formats are an advantage. Here, we present an open source, low-cost, adaptable, and easy to set-up system for combined behavioral tracking, electrophysiology and closed-loop stimulation.ApproachBased on the Open Ephys system (www.open-ephys.org) we developed multiple modules to include real-time tracking and behavior-based closed-loop stimulation. We describe the equipment and provide a step-by-step guide to set up the system. Combining the open source software Bonsai (bonsai-rx.org) for analyzing camera images in real time with the newly developed modules in Open Ephys, we acquire position information, visualize tracking, and perform tracking-based closed-loop stimulation experiments. To analyze the acquired data we provide an open source file reading package in Python.Main resultsThe system robustly visualizes real-time tracking and reliably recovers tracking information recorded from a range of sampling frequencies (30-1000Hz). We combined electrophysiology with the newly-developed tracking modules in Open Ephys to record place cell and grid cell activity in the hippocampus and in the medial entorhinal cortex, respectively. Moreover, we present a case in which we used the system for closed-loop optogenetic stimulation of entorhinal grid cells.SignificanceExpanding the Open Ephys system to include animal tracking and behavior-based closed-loop stimulation extends the availability of high-quality, low-cost experimental setup within standardized data formats serving the neuroscience community.

scholarly journals Toolkit for Oscillatory Real-time Tracking and Estimation (TORTE)

2021 ◽  
Author(s):  
Mark Schatza ◽  
Ethan Blackwood ◽  
Sumedh Nagrale ◽  
Alik S Widge
Keyword(s):  
Open Source ◽  
Real Time ◽  
Closed Loop ◽  
Brain Activity ◽  
Loop Control ◽  
Oscillatory Phase ◽  
Wide Range ◽  
Real Time Tracking ◽  
Therapeutic Tools ◽  
And Behavior

Closing the loop between brain activity and behavior is one of the most active areas of development in neuroscience. There is particular interest in developing closed-loop control of neural oscillations. Many studies report correlations between oscillations and functional processes. Oscillation-informed closed-loop experiments might determine whether these relationships are causal and would provide important mechanistic insights which may lead to new therapeutic tools. These closed-loop perturbations require accurate estimates of oscillatory phase and amplitude, which are challenging to compute in real time. We developed an easy to implement, fast and accurate Toolkit for Oscillatory Real-time Tracking and Estimation (TORTE). TORTE operates with the open-source Open Ephys GUI (OEGUI) system, making it immediately compatible with a wide range of acquisition systems and experimental preparations. TORTE efficiently extracts oscillatory phase and amplitude from a target signal and includes a variety of options to trigger closed-loop perturbations. Implementing these tools into existing experiments is easy and adds minimal latency to existing protocols. Most labs use in-house lab-specific approaches, limiting replication and extension of their experiments by other groups. Accuracy of the extracted analytic signal and accuracy of oscillation-informed perturbations with TORTE match presented results by these groups. However, TORTE provides access to these tools in a flexible, easy to use toolkit without requiring proprietary software. We hope that the availability of a high-quality, open-source, and broadly applicable toolkit will increase the number of labs able to perform oscillatory closed-loop experiments, and will improve the replicability of protocols and data across labs.

Dynamic Interaction in a Slewing Motor-Beam System: Closed Loop Control

1993 ◽  
Author(s):  
J. J. Sah ◽  
J. S. Lin ◽  
Agamemnon L. Crassidis ◽  
Roger W. Mayne
Keyword(s):  
Closed Loop ◽  
Gear Ratio ◽  
Dynamic Interaction ◽  
Closed Loop Control ◽  
Loop Control ◽  
Full State ◽  
Full State Feedback ◽  
Beam Interaction ◽  
Behavior Systems ◽  
And Behavior

Abstract This paper considers the dynamic interaction between a DC motor and its slewing beam load. The system is described in terms of dimensionless parameters which generalize the results and define the tendency for interaction between the motor and beam. The study focuses on the performance and behavior of the system under closed-loop control. Motor-beam arrangements with differing amounts of dynamic interaction are defined by simple adjustments in gear ratio for a specified motor and beam. Each of these systems is controlled with full state feedback and various forms of output feedback. Controller performance is optimized in each case and the systems are compared to evaluate the effect of motor-beam interaction on the closed-loop system behavior. Systems with an appropriate amount of motor-beam interaction tend to be easier to control and require modest amounts of actuation effort. Systems with little motor-beam interaction are especially prone to beam vibrations and require feedback of beam motions for good closed-loop performance. Those systems with excessive interaction require stabilization efforts to obtain good transient performance and tend to consume increased levels of actuation energy.

Closed-Loop Modeling of a Gulf of Mexico Reservoir Using Petrophysical Seismic Inversion

2009 ◽  
Author(s):  
Yuhong Liu ◽  
Michael Pelissier ◽  
Martha Barnes ◽  
Julian Robert Tribe ◽  
Richard Uden ◽  
...  
Keyword(s):  
Gulf Of Mexico ◽  
Closed Loop ◽  
Seismic Inversion ◽  
Loop Modeling

An Examination of How to Incorporate Ethics Into Systems Analysis and Vice Versa

2016 ◽  
Author(s):  
Richard A. Burgess ◽  
Mario G. Beruvides
Keyword(s):  
Systems Dynamics ◽  
Loop Modeling ◽  
Dynamics Modeling ◽  
Ethical Considerations ◽  
Cross Pollination ◽  
Systems Models ◽  
And Behavior ◽  
Combining Systems ◽  
Current Systems ◽  
Systems Dynamics Modeling

In their paper “Combining Systems Dynamics and Ethics: Towards More Science?” Erik Pruyt and Jan Kwakkel argue that ethics ought to play a larger role in systems dynamics and vice versa (2007). Including ethics, they contend, will add sensitivity to current systems models as well as provide guidance on how to achieve best outcomes; with respect to both efficiency and flourishing (Pruyt & Kwakkel, 2007). At first blush, such a cross pollination promises to add much needed depth of analysis to systems modeling and a higher degree of precision in ethical analyses. Not surprisingly, however, achieving such outcomes is more complex than it initially appears. Indeed, the quest for additional precision in ethical analysis is not a new one to philosophers and ethicists. The problem remains, in many ways, intractable. In Part I of this paper, the authors expand on Pruyt and Kwakkel’s thesis by examining specific insights and tools that can and should be incorporated into systems dynamics modeling. Emphasis will be placed on the mechanics of this inclusion and the resultant implications. Part II, then, focuses on how systems dynamics tools like causal loop modeling and behavior-over-time graphs can be incorporated into ethical analyses in a non-arbitrary manner. Finally, in Part III of the paper, the authors briefly discuss the ramifications of Parts I and II for engineering education; both among students and practicing engineers. The authors argue that both directions of the cross pollination have merit (especially the inclusion of ethical considerations in systems dynamics modeling) and ought to be developed further.

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