scholarly journals Factors Associated With Peripartum Virologic Suppression in Eastern Cape Province, South Africa: A Retrospective Cross-Sectional Analysis

2021 ◽  
Author(s):  
Oladele Vincent Adeniyi ◽  
Chikwelu Larry Obi ◽  
Daniel Ter Goon ◽  
Benson Iweriebor ◽  
Nonkosi Selanto-Chairman ◽  
...  
Keyword(s):  
Viral Suppression ◽  
Virologic Suppression ◽  
Eastern Cape Province ◽  
Eastern Cape ◽  
Child Transmission ◽  
Cross Sectional ◽  
Factors Associated ◽  
Undetectable Viremia ◽  
Sectional Analysis ◽  
Mother To Child

Abstract Background This study describes the characteristics of pregnant women on antiretroviral therapy (ART) and the rate of peripartum virologic suppression in a large prevention of mother-to-child transmission cohort who delivered in some selected maternity centers in Eastern Cape Province, South Africa. In addition, the study examines the factors associated with virologic suppression in the cohort. Methods This multicenter, retrospective cross-sectional analysis included medical data of 1709 women with human immunodeficiency virus between September 2015 and May 2016 in Eastern Cape Province. The main outcome measure was the rate of peripartum virologic suppression, defined as viral load (VL) <1000 copies/mL and undetectable viremia (VL <20 copies/mL). Correlates of peripartum virologic suppression and undetectable viremia were examined by fitting logistic regression model analysis. Results Of 1463 women with available VL results, the overall rate of peripartum suppression was 82%, and undetectable viremia was 56.9%. Being aged 24 years or younger (adjusted odds ratio [AOR], 0.68 [95% confidence interval {CI}, .48–.94]), smoking during pregnancy (AOR, 0.50 [95% CI, .28–.90]), and starting ART in the first trimester were associated with lower odds of viral suppression (<1000 copies/mL). Women who had never defaulted ART had an increased odds of having an undetectable VL (AOR, 3.09 [95% CI, 2.12–4.49]) and virologic suppression (AOR, 3.88 [95% CI, 2.62–5.74]) compared to those who defaulted. Conclusions More than half of the women achieved undetectable VL, and 4 in 5 women achieved viral suppression at delivery in the region. Early antenatal booking, combined with enhanced adherence support for pregnant women on ART, would be crucial toward achieving the goal of elimination of mother-to-child transmission in the region.

scholarly journals Mother-to-child transmission of HIV in Kenya: A cross-sectional analysis of the national database over nine years

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0183860 ◽  
Author(s):  
Matilu Mwau ◽  
Priska Bwana ◽  
Lucy Kithinji ◽  
Francis Ogollah ◽  
Samuel Ochieng ◽  
...  
Keyword(s):  
National Database ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis ◽  
Mother To Child

scholarly journals Sociodemographic and lifestyle correlates of exclusive breastfeeding practices among mothers on antiretroviral therapy in the Eastern Cape, South Africa

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Daniel Ter Goon ◽  
Anthony Idowu Ajayi ◽  
Oladele Vincent Adeniyi
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Exclusive Breastfeeding ◽  
Hiv Transmission ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Eastern Cape ◽  
Cross Sectional ◽  
Factors Associated ◽  
Breastfeeding Practice

Abstract Background Exclusive breastfeeding (EBF) is associated with a reduction of postnatal HIV transmission and optimal infant growth. Given that the factors influencing exclusive breastfeeding are multi-factorial and context-specific, we examined the prevalence and factors associated with exclusive breastfeeding practice in the first 6 months among mothers on antiretroviral therapy in the Eastern Cape, South Africa. Methods This was a cross-sectional study conducted between January to May 2018, on 469 parturient women enlisted in the prevention of mother-to-child HIV transmission cohort study in the Eastern Cape. Mothers were asked to recall whether they breastfed their infant exclusively with breast milk from birth and if so, to state how long they did. We collected relevant sociodemographic, lifestyle, and maternal information by interview. Bivariate and multivariable logistic regression analyses were fitted to determine the sociodemographic and lifestyle factors associated with exclusive breastfeeding practice. Results The prevalence of six-month exclusive breastfeeding, measured since birth, was 32.0%. E Exclusive breastfeeding’s prevalence was significantly higher among married women (36.8%), unemployed women (36.6%), non-smokers (32.7%), and those who never drank alcohol (37.0%). Unemployed women (adjusted odds ratio [AOR] 1.66, 95% Confidence Interval [CI] 1.08–2.56) and those with grade 12 or less level of education (AOR 2.76, 95% CI 1.02–7.49) had a higher likelihood of practising EBF for 6 months since birth while mothers who consumed alcohol (AOR 0.54, 95% CI 0.34–0.85) were less likely to practice EBF for 6 months. Conclusions The prevalence of six-month exclusive breastfeeding in the study, although comparable with sub-Saharan Africa and worldwide prevalence, remains suboptimal. Advocacy campaigns on EBF must target alcohol cessation and the creation of a favourable workplace environment for lactating mothers.

scholarly journals Factors Associated with Mother-to-child Transmission of Hepatitis B Virus Despite Immunoprophylaxis

2015 ◽  
Vol 54 (7) ◽  
pp. 711-716 ◽  
Author(s):  
Cui-Ping Liu ◽  
Yi-Lan Zeng ◽  
Min Zhou ◽  
Lan-Lan Chen ◽  
Rong Hu ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Factors Associated ◽  
B Virus ◽  
Mother To Child

scholarly journals Parental, child and socio-contextual factors associated with parenting self-efficacy among parents of children aged 0–7 years old: the CIKEO study

2021 ◽  
Author(s):  
Yuan Fang ◽  
Amy van Grieken ◽  
Irene N. Fierloos ◽  
Dafna A. Windhorst ◽  
Harrie Jonkman ◽  
...  
Keyword(s):  
Family Functioning ◽  
Self Efficacy ◽  
Contextual Factors ◽  
Cross Sectional ◽  
Mothers And Fathers ◽  
Factors Associated ◽  
Number Of Children ◽  
Effective Policy ◽  
Potential Factors ◽  
Sectional Analysis

Abstract Background A high parenting self-efficacy (PSE) has been associated with positive parenting and positive child development. However, there is limited and inconsistent information on factors associated with PSE. Objective To investigate factors associated with PSE in parents of children aged 0–7 years old, and to explore whether the associations were different between mothers and fathers. Methods We performed a cross-sectional analysis of the baseline data from a prospective cohort study: the CIKEO study. A total of 1012 parents (mean age = 33.8, SD = 5.0) completed self-reported measure of PSE and 18 potential factors associated with PSE. Results Multivariable models revealed that lower parenting stress, fewer child behavior problems, better eating behavior, better parental and child general health, a smaller number of children living in the household, higher perceived level of social support and having a migration background were associated with higher levels of PSE (p < 0.05). The association between family functioning and PSE differed between mothers and fathers (p for interaction = 0.003): with beta and 95% confidence interval being: 1.29 (− 2.05, 0.87), and 0.23 (− 0.46, 3.29), respectively. Conclusions A range of parental, child and social-contextual factors in relation to PSE were identified. The patterns of associations for most of the factors were similar among mothers and fathers. However, the association between family functioning and PSE might differ for mothers and fathers. Our findings are relevant for tailoring and implementing successful interventions and effective policy making in child care. Trial registration Netherlands National Trial Register number NL7342. Date of registration: 05-November-2018, retrospectively registered.

scholarly journals Prevalence and Risk Factors Associated With Hypertension in Hemophilia: Cross-Sectional Analysis of a National Discharge Register

2016 ◽  
Vol 23 (7) ◽  
pp. 871-875 ◽  
Author(s):  
Craig D. Seaman ◽  
Mariya Apostolova ◽  
Jonathan Yabes ◽  
Diane M. Comer ◽  
Margaret V. Ragni
Keyword(s):  
Risk Factors ◽  
Cross Sectional ◽  
Factors Associated ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

scholarly journals Involvement of Male Partners of Pregnant Women in the Prevention of Mother-to-Child Transmission (PMTCT) of HIV in Haiti: A Mixed-Methods Study

2021 ◽  
Vol 15 (2) ◽  
pp. 155798832110060
Author(s):  
Patrice Ngangue ◽  
Middle Fleurantin ◽  
Rheda Adekpedjou ◽  
Leonel Philibert ◽  
Marie-Pierre Gagnon
Keyword(s):  
Mixed Methods ◽  
Pregnant Women ◽  
Male Involvement ◽  
Mixed Methods Study ◽  
Mother To Child Transmission ◽  
Male Partners ◽  
Hiv Status ◽  
Child Transmission ◽  
Factors Associated ◽  
Mother To Child

This mixed-methods study aimed to determine the level of male involvement in the prevention of mother-to-child transmission (PMTCT) services in Haiti and identify barriers and associated factors. From May to June 2018, a questionnaire was used to measure the level of male involvement. Semistructured interviews with pregnant women were also conducted. Multivariate linear regression and qualitative content analyses were performed to explore factors associated and barriers to male partners’ involvement in PMTCT services. One hundred and two pregnant women living with HIV completed the questionnaire. About 47% of male partners had a high level of involvement. Specifically, 90% financially supported their spouse, and 82% knew her appointment date at the antenatal clinic (ANC). Only 25% of male partners accompanied their spouse to the ANC, and 19% routinely used a condom during sexual intercourse. Factors associated with male involvement in PMTCT were being married and sharing HIV status with the male partner. Male partners with a positive HIV status were more likely to be involved in PMTCT. Qualitative findings revealed that barriers to male involvement included the conflict between opening hours of the ANC and the male partner’s schedule, waiting time at the ANC, and the perception of antenatal care as being women’s business. Overall male partners’ involvement in PMTCT services is moderate. Gender relations, sociocultural beliefs, and care organization are likely to hinder this involvement. Developing and implementing contextually and culturally accepted strategies for male partners of pregnant women could contribute to strengthening their involvement in the PMTCT program.

scholarly journals Factors influencing the utilisation of prevention of mother-to-child transmission (PMTCT) services by pregnant women in the Eastern Cape, South Africa

2005 ◽  
Vol 10 (1) ◽  
Author(s):  
Karl Peltzer ◽  
Donald Skinner ◽  
Sakhumzi Mfecane ◽  
Olive Shisana ◽  
Ayanda Nqeketo ◽  
...  
Keyword(s):  
South Africa ◽  
Pregnant Women ◽  
Full Text ◽  
Resource Poor Setting ◽  
Eastern Cape ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Factors Influencing ◽  
Resource Poor ◽  
Mother To Child

The aim of the study was to identify factors influencing the utilisation of Prevention of Mother-to-Child Transmission (PMTCT) in a resource poor setting in South Africa. Opsomming Die doel van die studie was om faktore te identifiseer wat die benutting van die Voorkoming van Moeder-tot-Kind Oordrag (VMTKO) beïnvloed in ‘n omgewing in Suid-Afrika wat arm is aan hulpbronne. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

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