scholarly journals A Phase 2 Trial of Oral Solithromycin 1200 mg or 1000 mg as Single-Dose Oral Therapy for Uncomplicated Gonorrhea

2015 ◽  
Vol 61 (7) ◽  
pp. 1043-1048 ◽  
Author(s):  
Edward W. Hook ◽  
Matthew Golden ◽  
Brian D. Jamieson ◽  
Paula B. Dixon ◽  
Hanne S. Harbison ◽  
...  
Keyword(s):  
Single Dose ◽  
Oral Therapy ◽  
Phase 2 ◽  
Phase 2 Trial ◽  
Dose Oral ◽  
Uncomplicated Gonorrhea

Comparison of single-dose oral grepafloxacin with cefixime for treatment of uncomplicated gonorrhea in men. The STD Study Group.

1997 ◽  
Vol 41 (8) ◽  
pp. 1843-1845 ◽  
Author(s):  
E W Hook ◽  
W M McCormack ◽  
D Martin ◽  
R B Jones ◽  
K Bean ◽  
...  
Keyword(s):  
Single Dose ◽  
Neisseria Gonorrhoeae ◽  
Open Study ◽  
Study Group ◽  
Dose Oral ◽  
Male Patients ◽  
Resistant Strains ◽  
Oral Doses ◽  
Uncomplicated Gonorrhea

In a randomized open study, 351 male patients with uncomplicated gonorrhea were given single oral doses of grepafloxacin (400 mg) or cefixime (400 mg). In the 299 microbiologically evaluable patients, urethral infections were cured in 99% (147 of 149) of those receiving grepafloxacin and 97% (145 of 150) of those given cefixime. Eradication rates for both regimens were 100% in the 16% (47 of 299) of participants who were infected with penicillin-resistant Neisseria gonorrhoeae and 97% in the 21% (62 of 299) of participants infected with tetracycline-resistant strains. Grepafloxacin is a well-tolerated alternative to cefixime for treatment of uncomplicated gonorrhea in males.

scholarly journals Efficacy and Safety of Single-Dose Oral Delafloxacin Compared With Intramuscular Ceftriaxone for Uncomplicated Gonorrhea Treatment

2019 ◽  
Vol 46 (5) ◽  
pp. 279-286 ◽  
Author(s):  
Edward W. Hook ◽  
Matthew R. Golden ◽  
Stephanie N. Taylor ◽  
Eugenia Henry ◽  
Carol Tseng ◽  
...  
Keyword(s):  
Single Dose ◽  
Efficacy And Safety ◽  
Dose Oral ◽  
Uncomplicated Gonorrhea

Phase 2 trial of chronic low-dose oral etoposide as salvage therapy of platinum-refractory ovarian cancer

1992 ◽  
Vol 119 (1) ◽  
pp. 55-57 ◽  
Author(s):  
Maurie Markman ◽  
Thomas Hakes ◽  
Bonnie Reichman ◽  
John Curtin ◽  
Richard Barakat ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Salvage Therapy ◽  
Low Dose ◽  
Oral Etoposide ◽  
Phase 2 ◽  
Phase 2 Trial ◽  
Dose Oral ◽  
Platinum Refractory

Clinical Evaluation of Single-Dose Oral Bacampicillin or Ampicillin in Therapy of Uncomplicated Gonorrhea

1981 ◽  
Vol 3 (1) ◽  
pp. 166-169 ◽  
Author(s):  
K. F. Wagner ◽  
G. Counts ◽  
K. K. Holmes ◽  
P. F. Sparling ◽  
L. O. Gentry ◽  
...  
Keyword(s):  
Single Dose ◽  
Clinical Evaluation ◽  
Dose Oral ◽  
Uncomplicated Gonorrhea

Fleroxacin in single dose oral therapy of uncomplicated lower urinary tract infection

1988 ◽  
Vol 22 (Supplement_D) ◽  
pp. 219-221 ◽  
Author(s):  
J. Kosmidis ◽  
P. Gargalianos ◽  
G. Adamis ◽  
D. Petropoulou ◽  
D. Makris
Keyword(s):  
Urinary Tract Infection ◽  
Single Dose ◽  
Urinary Tract ◽  
Tract Infection ◽  
Lower Urinary Tract ◽  
Oral Therapy ◽  
Lower Urinary Tract Infection ◽  
Dose Oral ◽  
Lower Urinary

scholarly journals Eliglustat, an investigational oral therapy for Gaucher disease type 1: Phase 2 trial results after 4years of treatment

2014 ◽  
Vol 53 (4) ◽  
pp. 274-276 ◽  
Author(s):  
Elena Lukina ◽  
Nora Watman ◽  
Marta Dragosky ◽  
Gregory M. Pastores ◽  
Elsa Avila Arreguin ◽  
...  
Keyword(s):  
Gaucher Disease ◽  
Oral Therapy ◽  
Disease Type ◽  
Phase 2 ◽  
Phase 2 Trial ◽  
Gaucher Disease Type 1
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