Recovery of Severe Dialysis Disequilibrium Syndrome with Uncal Herniation Following Therapy with Mannitol, Hyperventilation and Hypertonic Saline
Keyword(s):
Abstract Dialysis disequilibrium syndrome (DDS) is a rare complication of dialysis, especially with the general application of preventive strategies. Severe DDS with brain herniation is believed to be fatal. We present a patient presenting with bilateral uncal herniation after receiving two dialysis sessions with low-efficiency settings. The serial brain magnetic resonance imaging studies showed the temporal evolution of DDS-induced cerebral edema. With aggressive treatment of hypertonic saline and mannitol, the patient made a remarkable recovery. This case highlights that we should be cautious about this severe complication of dialysis even with preventive strategies, and recovery is possible with prompt recognition and treatment.
2003 ◽
Vol 30
(4)
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pp. 384-387
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