A Quality-Control Program Based on the Use of Desk-Top Digital Computer

Abstract Programs written for a relatively inexpensive desk-top computer are used to calculate the chemical concentration of any batch of unknowns from a flattened absorbance curve with up to five points produced by single- or dual-channel continuous-flow analyzers and other instrumentation. Any value beyond the limits of the curve is rejected. The programs are then used to evaluate a pooled control serum from previously programmed standard deviation data. The sequence of calculation is such that computation of patient samples stops if the control value lies outside these programmed limits. The system ensures that no patient sample is reported, or even calculated, unless its accompanying control was within acceptable statistical limits. Acceptance of the system by technologists has been outstanding.

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Standards versus Standardised Methods in Enzyme Assay

Annals of Clinical Biochemistry International Journal of Laboratory Medicine ◽

10.1177/000456328302000108 ◽

1983 ◽

Vol 20 (1) ◽

pp. 52-59 ◽

Cited By ~ 15

Author(s):

R T P Jansen ◽

A P Jansen

Keyword(s):

Quality Control ◽

Alkaline Phosphatase ◽

Creatine Kinase ◽

Lactate Dehydrogenase ◽

Alanine Aminotransferase ◽

Enzyme Assay ◽

Control Program ◽

Internal Quality ◽

Quality Control Program ◽

Control Serum

In a trial of the Netherlands coupled external/internal quality control program a control serum and an enzyme standard were analysed over a period of eight weeks, five times each week. Five enzymes were determined: alkaline phosphatase, creatine kinase, lactate dehydrogenase, alanine aminotransferase, and γ-glutamyltransferase. The measured values in the serum were converted to the standards. Those laboratories using the recommended methods also submitted their non-transformed serum values. The following standardisation techniques have been compared: ( a) no standardisation of methodology but use of enzyme standards; ( b) standardisation of methodology; ( c) standardisation of methodology combined with use of an enzyme standard. Results were submitted to analysis of variance. Standardisation of methodology did not yield smaller interlaboratory variation than the standardisation with enzyme standards. In this trial a combination of both standardisation techniques yielded generally better results. Results for γ-glutamyltransferase indicate that standardisation of substrate may be necessary apart from the use of an enzyme standard. The preparation of stable enzyme standards is stressed.

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EDTA Titration of Calcium and Magnesium: Determination of Calcium in Canned Tomatoes

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/53.4.720 ◽

1970 ◽

Vol 53 (4) ◽

pp. 720-720

Author(s):

Edward F Steagall

Keyword(s):

Quality Control ◽

Standard Deviation ◽

Drug Administration ◽

Food Additives ◽

Control Program ◽

Mean Value ◽

Quality Control Program ◽

Edta Titration ◽

Calcium And Magnesium

Abstract This past year a food additives quality control program was established for Food and Drug Administration field laboratories; one phase involved the determination of calcium in canned whole tomatoes. One can of tomatoes containing declared added calcium and one can without added calcium were each analyzed by 18 participating laboratories. Results on the cans with added calcium showed a mean value of 0.031% with a standard deviation of ±0.0032%. Results on t he cans without added calcium showed a mean value of 0.005% with a standard deviation of ±0.0039%.

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PENGENDALIAN MUTU BIDANG MIKROBIOLOGI KLINIK

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY ◽

10.24293/ijcpml.v12i2.851 ◽

2018 ◽

Vol 12 (2) ◽

pp. 92

Author(s):

Prihatini Prihatini

Keyword(s):

Quality Control ◽

Clinical Chemistry ◽

Control Program ◽

Reference Laboratory ◽

Quality Control Program ◽

Control Value

The quality control program in microbiology are procedures to identify microorganism,monitoring,to asses laboratory competencein handling clinical materials, other methods needed.QC is essential in bacteriology because nature, unlike clinical chemistry andhematology QC’s, because can’t compare with control value. The QC in microbiology include preparation of pra-analitics,analitics andpost-analitics which depending to personal, material,SOP and micoorganism Specimens, laboratory Instruments like incubators, freezer,autoclaves, must be good preparations. Examinations use control standard, monitoring all of themes periodically The laboratory resultswere recorded and evaluated as reference laboratory. The QC microbiology have been presented, they need large budgets to validity oflaboratory results.

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