scholarly journals Can Homeopathic Arsenic Remedy Combat Arsenic Poisoning in Humans Exposed to Groundwater Arsenic Contamination?: A Preliminary Report on First Human Trial

2005 ◽  
Vol 2 (4) ◽  
pp. 537-548 ◽  
Author(s):  
Anisur Rahman Khuda-Bukhsh ◽  
Surajit Pathak ◽  
Bibhas Guha ◽  
Susanta Roy Karmakar ◽  
Jayanta Kumar Das ◽  
...  
Keyword(s):  
Preliminary Report ◽  
West Bengal ◽  
Reduced Glutathione ◽  
Free Water ◽  
Marker Enzymes ◽  
Human Trial ◽  
Groundwater Arsenic ◽  
Aspartate Amino Transferase ◽  
Globally Distributed ◽  
Phosphatase Alkaline

Groundwater arsenic (As) has affected millions of people globally distributed over 20 countries. In parts of West Bengal (India) and Bangladesh alone, over 100 million people are at risk, but supply of As-free water is grossly inadequate. Attempts to remove As by using orthodox medicines have mostly been unsuccessful. A potentized homeopathic remedy, Arsenicum Album-30, was administered to a group of As affected people and thereafter the As contents in their urine and blood were periodically determined. The activities of various toxicity marker enzymes and compounds in the blood, namely aspartate amino transferase, alanine amino transferase, acid phosphatase, alkaline phosphatase, lipid peroxidation and reduced glutathione, were also periodically monitored up to 3 months. The results are highly encouraging and suggest that the drug can alleviate As poisoning in humans.

GROUNDWATER ARSENIC IN SHALLOW AQUIFERS OF BENGAL DELTA PLAIN (WEST BENGAL): A MICROBIOLOGICAL APPROACH

2016 ◽  
Author(s):  
Jishnu Adhikari ◽  
◽  
Debashis Chatterjee ◽  
Shilajit Barua ◽  
Thomas R. Kulp
Keyword(s):  
West Bengal ◽  
Shallow Aquifers ◽  
Bengal Delta ◽  
Delta Plain ◽  
Groundwater Arsenic

scholarly journals Groundwater arsenic contamination in Bangladesh and West Bengal, India.

2000 ◽  
Vol 108 (5) ◽  
pp. 393-397 ◽  
Author(s):  
U K Chowdhury ◽  
B K Biswas ◽  
T R Chowdhury ◽  
G Samanta ◽  
B K Mandal ◽  
...  
Keyword(s):  
West Bengal ◽  
Arsenic Contamination ◽  
Groundwater Arsenic

Organic carbon induced mobilization of iron and manganese in a West Bengal aquifer and the muted response of groundwater arsenic concentrations

2014 ◽  
Vol 367 ◽  
pp. 51-62 ◽  
Author(s):  
Harald Neidhardt ◽  
Zsolt Attila Berner ◽  
Dominik Freikowski ◽  
Ashis Biswas ◽  
Santanu Majumder ◽  
...  
Keyword(s):  
Organic Carbon ◽  
West Bengal ◽  
Groundwater Arsenic ◽  
Iron And Manganese

Heinz Body Anemia and Methemoglobinemia in Ponies Given Red Maple (Acer rubrum L.) Leaves

1982 ◽  
Vol 19 (5) ◽  
pp. 521-533 ◽  
Author(s):  
L. W. George ◽  
T. J. Divers ◽  
E. A. Mahaffey ◽  
M. J. H. Suarez
Keyword(s):  
Body Weight ◽  
Plasma Protein ◽  
Reduced Glutathione ◽  
Clinical Signs ◽  
Acer Rubrum ◽  
Serum Levels ◽  
Red Maple ◽  
Heinz Bodies ◽  
Aspartate Amino Transferase ◽  
Erythrocyte Fragility

Ponies given dried red maple ( Acer rubrum L.) leaves at a dose of 3.0 gm/kg body weight became ill and died one to five days after administration of the leaves. Two clinical patterns of disease were seen. Ponies given dried leaves collected after September 15 died by 18 hours, while ponies given dried leaves collected before September 15 became ill with a hemolytic syndrome and died by three to five days. Freshly harvested leaves administered immediately after collection did not produce disease in ponies, but when dried, they became toxic and remained so for at least 30 days. Overnight freezing did not alter the toxicity of the leaves. Leaves were toxic when administered at doses of 1.5 gm/kg of body weight. The clinical signs of ponies with the hemolytic syndrome included polypnea, tachycardia, icterus, cyanosis, scleral petechiation, and brownish discoloration of the urine and blood. Blood changes of ponies with the hemolytic syndrome included anemia, hemoglobinemia, Heinz bodies, depletion of erythrocyte reduced glutathione, increased erythrocyte fragility, and increased serum levels of aspartate amino transferase, sorbitol dehydrogenase, plasma protein, and bilirubin. Lesions of ponies that died from the hemolytic syndrome included icterus, centrilobular hepatic degeneration, hemoglobinemic nephrosis, and erythrophagocytosis by splenic, adrenal, and hepatic phagocytes. Only brownish discoloration of the blood and mild centrilobular hepatic degeneration were observed in the four ponies that died peracutely.

scholarly journals ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 ◽  
Vol 61 (1) ◽  
pp. 201-212 ◽  
Author(s):  
Alain Amar-Costesec ◽  
Henri Beaufay ◽  
Maurice Wibo ◽  
Denise Thinès-Sempoux ◽  
Ernest Feytmans ◽  
...  
Keyword(s):  
Analytical Study ◽  
Microsomal Fraction ◽  
Chemical Constituents ◽  
Microsomal Protein ◽  
High Yield ◽  
Marker Enzymes ◽  
Cytoplasmic Granules ◽  
Liver Homogenates ◽  
Nadph Cytochrome C Reductase ◽  
Phosphatase Alkaline

Liver homogenates have been submitted to quantitative fractionation by differential centrifugation. Three particulate fractions: N (nuclear), ML (large granules), and P (microsomes), and a final supernate (S) have been obtained. The biochemical composition of the microsomal fraction has been established from the assay and distribution pattern of 25 enzymatic and chemical constituents. These included marker enzymes for mitochondria (cytochrome oxidase), lysosomes (acid phosphatase and N-acetyl-ß-glucosaminidase), and peroxisomes (catalase). The microsomal preparations were characterized by a moderate contamination with large cytoplasmic granules (only 6.2% of microsomal protein) and by a high yield in microsomal components. Enzymes such as glucose 6-phosphatase, nucleoside diphosphatase, esterase, glucuronyltransferase, NADPH cytochrome c reductase, aminopyrine demethylase, and galactosyltransferase were recovered in the microsomes to the extent of 70% or more. Another typical behavior was shown by 5'-nucleotidase, alkaline phosphatase, alkaline phosphodiesterase I, and cholesterol, which exhibited a "nucleomicrosomal" distribution. Other complex distributions were obtained for several constituents recovered in significant amount in the microsomes and in the ML or in the S fraction.

scholarly journals Groundwater Arsenic Contamination in West Bengal: Current Scenario, Effects and Probable Ways of Mitigation

2014 ◽  
Vol 13 ◽  
pp. 45-58 ◽  
Author(s):  
Tanmoy Kumar Dey ◽  
Priya Banerjee ◽  
Madhurima Bakshi ◽  
Abhirupa Kar ◽  
Somdeep Ghosh
Keyword(s):  
Drinking Water ◽  
Chronic Exposure ◽  
West Bengal ◽  
Contaminated Water ◽  
Safe Drinking Water ◽  
Essential Step ◽  
The Past ◽  
Groundwater Arsenic ◽  
Current Scenario ◽  
Mind Set

During the past two decades, Arsenic (As) contamination via groundwater has become a serious issue worldwide and is now a major concern in the Indo-Bangladesh Gangetic delta. Arsenic enters human body through contaminated groundwater consumed as drinking water. Food safety in this region is also facing severe consequences as bio-accumulation of Arsenic is occurring in food crops irrigated with As-contaminated water. Chronic exposure to Arsenic can cause not only cancerous and non-cancer health effects. Reports suggest that about 20 % population in West Bengal is highly affected. Various techniques are being introduced to provide arsenic-free drinking water at an affordable cost. But a rigorous change in habit and mind set for procuring safe drinking water in those surviving in As-contaminated zones is the most essential step towards curbing the fatal consequences of As exposure. Harvesting rain water and utilization of proper purification techniques can be considered a possible alternative of safe drinking water.

Groundwater Arsenic Contamination and Sufferings of People in West Bengal, India and Bangladesh

1999 ◽  
pp. 41-65 ◽  
Author(s):  
Badal K. Mandai ◽  
Bhaja K. Biswas ◽  
Ratan K. Dhar ◽  
Tarit Roy Chowdhury ◽  
Gautam Samanta ◽  
...  
Keyword(s):  
West Bengal ◽  
Arsenic Contamination ◽  
Groundwater Arsenic
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