scholarly journals Normal and reference values for MRI-based pulse wave velocity in the middle-aged general population

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
M.J.P Van Hout ◽  
I.A Dekkers ◽  
J.J.M Westenberg ◽  
M.J Schalij ◽  
R De Mutsert ◽  
...  
Keyword(s):  
Blood Pressure ◽  
General Population ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Funding Source ◽  
Clinical Implementation ◽  
Research Profile ◽  
Cv Disease

Abstract Background Aortic stiffness, assessed through pulse wave velocity (PWV), is an independent predictor for cardiovascular (CV) risk. However, the scarce availability of normal and reference values for magnetic resonance imaging (MRI) based PWV is limiting clinical implementation. Purpose The aim of this study was to determine normal and reference values for MRI-PWV in the general population. Methods From the 2,484 participants of the NEO study that have available MRI-PWV data, we selected 1,639 participants that were free from CV disease or treatment for diabetes, hypertension or dyslipidaemia (age range 45–65 years, 51% male). Participants were categorized by sex, age and blood pressure (BP) subgroups. Normal values were specified for healthy (<130/80 mmHg) and elevated BP (≥130/80 and <140/90 mmHg) and reference values for high BP (≥140/90 mmHg) subgroups. Differences between groups were tested with either an independent samples t-test or ANOVA. Results Overall mean PWV was 6.5 m/s [95% CI 6.4–6.6]. PWV increased significantly with advancing age and BP categories (both p<0.001). There was no difference in PWV between men and women, however a stronger increasing trend for women above 55 years old was observed (figure). The 95% CI's were smaller for participants <55 years old as compared to participants >55, indicating an increasing variability of PWV with age. The elevated PWV upper limits for the higher blood pressure subgroups are particularly evident in participants above 55 years old. Conclusion This study provides normal and reference values for MRI-assessed PWV per sex, age and blood pressure category. PWV percentiles (10, 25, 50, 75 and 90th) Funding Acknowledgement Type of funding source: Public hospital(s). Main funding source(s): The NEO study is supported by the participating departments, the Division and the Board of Directors of the Leiden University Medical Centre, and by the Leiden University, Research Profile Area “Vascular and Regenerative Medicine”

scholarly journals Normal and reference values for cardiovascular magnetic resonance-based pulse wave velocity in the middle-aged general population

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Max J. van Hout ◽  
Ilona A. Dekkers ◽  
Jos J. Westenberg ◽  
Martin J. Schalij ◽  
Ralph L. Widya ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
General Population ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Disease Risk ◽  
Cardiovascular Disease Risk

Abstract Background Aortic stiffness, assessed through pulse wave velocity (PWV), is an independent predictor for cardiovascular disease risk. However, the scarce availability of normal and reference values for cardiovascular magnetic resonance imaging (CMR) based PWV is limiting clinical implementation. The aim of this study was to determine normal and reference values for CMR assessed PWV in the general population. Methods From the 2,484 participants of the Netherlands Epidemiology of Obesity (NEO) study that have available CMR-PWV data, 1,394 participants free from cardiovasculard disease, smokers or treatment for diabetes, hypertension or dyslipidaemia were selected (45–65 years, 51% female). Participants were divided into sex, age and blood pressure (BP) subgroups. Normal values were specified for participants with a BP < 130/80 mmHg and reference values for elevated BP subgroups (≥ 130/80 and < 140/90 mmHg; and ≥ 140/90 mmHg). Differences between groups were tested with independent samples t-test or ANOVA. Due to an oversampling of obese individuals in this study, PWV values are based on a weighted analysis making them representative of the general population. Results Normal mean PWV was 6.0 m/s [95% CI 5.8–6.1]. PWV increased with advancing age and BP categories (both p < 0.001). There was no difference between sex in normal PWV, however in the BP > 140/90 mmHg women had a higher PWV (p = 0.005). The interpercentile ranges were smaller for participants < 55 years old compared to participants ≥ 55 years, indicating an increasing variability of PWV with age. PWV upper limits were particularly elevated in participants ≥ 55 years old in the high blood pressure subgroups. Conclusion This study provides normal and reference values for CMR-assessed PWV per sex, age and blood pressure category in the general population.

scholarly journals Pulse Wave Velocity as Marker of Preclinical Arterial Disease: Reference Levels in a Uruguayan Population Considering Wave Detection Algorithms, Path Lengths, Aging, and Blood Pressure

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Ignacio Farro ◽  
Daniel Bia ◽  
Yanina Zócalo ◽  
Juan Torrado ◽  
Federico Farro ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Normal Population ◽  
Blood Pressure Level ◽  
Study Time ◽  
Lipid Lowering ◽  
Clinical Implementation ◽  
Age Related

Carotid-femoral pulse wave velocity (PWV) has emerged as the gold standard for non-invasive evaluation of aortic stiffness; absence of standardized methodologies of study and lack of normal and reference values have limited a wider clinical implementation. This work was carried out in a Uruguayan (South American) population in order to characterize normal, reference, and threshold levels of PWV considering normal age-related changes in PWV and the prevailing blood pressure level during the study. A conservative approach was used, and we excluded symptomatic subjects; subjects with history of cardiovascular (CV) disease, diabetes mellitus or renal failure; subjects with traditional CV risk factors (other than age and gender); asymptomatic subjects with atherosclerotic plaques in carotid arteries; patients taking anti-hypertensives or lipid-lowering medications. The included subjects (n=429) were categorized according to the age decade and the blood pressure levels (at study time). All subjects represented the “reference population”; the group of subjects with optimal/normal blood pressures levels at study time represented the “normal population.”Results. Normal and reference PWV levels were obtained. Differences in PWV levels and aging-associated changes were obtained. The obtained data could be used to define vascular aging and abnormal or disease-related arterial changes.

Reference values of office central blood pressure, pulse wave velocity, and augmentation index recorded by means of the Mobil‐O‐Graph PWA monitor

2020 ◽  
Vol 43 (11) ◽  
pp. 1239-1248
Author(s):  
Annelise M. G. Paiva ◽  
Marco A. Mota-Gomes ◽  
Andréa A. Brandão ◽  
Fábio S. Silveira ◽  
Marcos S. Silveira ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pressure Pulse ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Central Blood Pressure

scholarly journals Reference values of brachial-ankle pulse wave velocity according to age and blood pressure in a central Asia population

PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0171737 ◽  
Author(s):  
Gulinuer Yiming ◽  
Xianhui Zhou ◽  
Wenkui Lv ◽  
Yi Peng ◽  
Wenhui Zhang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Central Asia ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave

scholarly journals Pulse Wave Velocity and Central Blood Pressure: Normal and Reference Values in Older People in Spain

2018 ◽  
Vol 71 (12) ◽  
pp. 1084-1086
Author(s):  
Mercedes Sánchez-Martínez ◽  
Juan J. Cruz ◽  
Auxiliadora Graciani ◽  
Esther López-García ◽  
Fernando Rodríguez-Artalejo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Older People ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Central Blood Pressure

Pulse wave velocity and blood pressure in athletes performing endurance and intense resistance training

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Said Ouamer ◽  
M.K Guerchani Mohamed Karim ◽  
D Djermane ◽  
S Benkhedda
Keyword(s):  
Blood Pressure ◽  
Young Adults ◽  
Resistance Training ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Funding Source ◽  
Blood Pressures ◽  
The Impact

Abstract Background There have been contradictory reports regarding the impact of intense resistance exercise on arterial stiffness. We examined the effects of long-term endurance training and intense resistance training on central hemodynamic in athletes compared with healthy sedentary controls. Purpose We hypothesized that young adults participating in endurance sports would have decreased arterial stiffness, whereas those participating in intense resistance sports would have increased arterial stiffness. Methods One hundred thirty participants (20–30 years) including 46 intense resistance trained athletes (IRTA) (weight-lifters), 42 endurance trained athletes (ETA) (long and mid-long distance runners) and 42 sedentary individuals (SED) were investigated by aplanation tonometry and pulse wave analysis; aortic pulse wave velocity (PWV) was measured. Differences were tested by analysis of variance, covariance and multiple linear regressions after adjustment for confounders. The t-test and chi-square test were used to compare the different parameters studied between men and women. The difference between the types of sport in the female subgroup was tested by the Kruskall Wallis test. Quantitative data were expressed as means ±standard deviation or median Results There were no differences among all 3 groups regarding age, height, glucose, cholesterol and triglyceride levels. Anthropometrics were higher in IRTA compared to ETA. Heart rates at rest and augmentation index were lower in trained participants than in sedentary individuals. Brachial and aortic blood pressures were lower in ETA compared to IRTA. Aortic PWV was significantly lower (p&lt;0.05) in ETA (mean ±SD: 5.58±1.00 m/s) compared to IRTA (7.06±0.87 m/s) and SED (7.18±1.06 m/s). The results of the statistical analysis in female subjects in the different groups were comparable to those found in men. A subgroup analysis comparing women and men found comparable results for PWV, but women had higher HR at rest and lower brachial and central blood pressures compared to men. After multiple regression analysis, diastolic blood pressure (DBP) remained the only hemodynamic parameter correlated to PWV, whatever the group. Conclusion Aortic stiffness is influenced by exercise modalities since ETA had better PWV than IRTA in both sexes. DBP is an important determinant and potential mediator of arterial stiffening in young adults. Funding Acknowledgement Type of funding source: Public hospital(s). Main funding source(s): No funding sources

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