Interplay between right atrial function and liver stiffness in adults with repaired right ventricular outflow obstructive lesions

Author(s):  
Vivian Wing-Yi Li ◽  
Edwina Kam-Fung So ◽  
Wenxi Li ◽  
Pak-Cheong Chow ◽  
Yiu-Fai Cheung

Abstract Aims This study determined the associations between right atrial (RA) and right ventricular (RV) mechanics and liver stiffness in adults with repaired tetralogy of Fallot (TOF), pulmonary atresia with intact ventricular septum (PAVIS), and pulmonary stenosis (PS). Methods and results Ninety subjects including 26 repaired TOF, 24 PAIVS, and 20 PS patients and 20 controls were studied. Hepatic shear wave velocity and tissue elasticity (E), measures of liver stiffness, were assessed by two-dimensional shear wave elastography, while RA and RV mechanics were assessed by speckle tracking echocardiography. Deformation analyses revealed worse RV systolic strain and strain rate, and RA peak positive and total strain, and strain rates at ventricular systole and at early diastole in all of the patient groups compared with controls (all P < 0.05). Compared with controls, all of the patient groups had significantly greater shear wave velocity and hepatic E-value (all P < 0.05). Shear wave velocity and hepatic E-value correlated negatively with RV systolic strain rate, and RA positive strain, total strain, and strain rate at ventricular systole and at early diastole (all P < 0.05). Multivariate analyses revealed RA strain rate at early diastole (P = 0.015, P < 0.001), maximum RA size (P < 0.001, P < 0.001), and severity of pulmonary regurgitation (P = 0.05, Pp = 0.014) as significant correlates of shear wave velocity and hepatic E-value. Conclusion In adults with repaired TOF, PAIVS, and PS, RA dysfunction and pulmonary regurgitation are associated with liver stiffness.

2016 ◽  
Vol 18 (2) ◽  
pp. 151 ◽  
Author(s):  
Mariana M Gersak ◽  
Erich Sorantin ◽  
Jana Windhaber ◽  
Sorin M Dudea ◽  
Michael Riccabona

Aim: Food intake and acutely decompensated cardiac failure may impair liver stiffness estimations, mainly because these methods are influenced by liver blood flow variation encountered in these conditions. It is well known that also during physical effort liver blood flow changes, due to the redistribution of blood flow mainly to the skeletal muscles. The aim of this study is to assess the change of liver shear- wave velocities immediately after cessation of an acute physical effort. A secondary aim was to find the proper timing for accurate liver stiffness estimation after physical exhaustion. Material and methods: Liver shear-wave velocities were measured using virtual touch quantification (VTQ) in seven apparently healthy volunteers, in fasting conditions. All subjects underwent a complete abdominal ultrasound study, including the liver VTQ. Then, all subjects performed a spiroergometry and thereafter, another series of three liver shear-wave velocity measurements were performed: immediately after spiroergometry, five min, and ten min after spiroergometry, respectively. Results: Before spiroergoemetry, the mean liver shear-wave velocity was 1.05±0.12 m/sec. Immediately after spiroergometry, mean liver shear-wave velocities increased significantly, measuring 1.34±0.16 m/sec (p <0.01). The mean liver shear-wave velocities at five and ten minutes after exhausting were 1.23±0.14 m/sec and 1.05±0.11 m/sec respectively. Conclusions: Liver stiffness estimation using VTQ was influenced by acute physical exercise in our study group. Despite the small number of subjects, the preliminary results show that if patients had done physical effort before VTQ elastography, they should rest at least ten minutes before reliable liver stiffness estimations can be performed.


Solid Earth ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 379-390 ◽  
Author(s):  
Yaniv Darvasi ◽  
Amotz Agnon

Abstract. Instrumental strong motion data are not common around the Dead Sea region. Therefore, calibrating a new attenuation equation is a considerable challenge. However, the Holy Land has a remarkable historical archive, attesting to numerous regional and local earthquakes. Combining the historical record with new seismic measurements will improve the regional equation. On 11 July 1927, a rupture, in the crust in proximity to the northern Dead Sea, generated a moderate 6.2 ML earthquake. Up to 500 people were killed, and extensive destruction was recorded, even as far as 150 km from the focus. We consider local near-surface properties, in particular, the shear-wave velocity, as an amplification factor. Where the shear-wave velocity is low, the seismic intensity far from the focus would likely be greater than expected from a standard attenuation curve. In this work, we used the multichannel analysis of surface waves (MASW) method to estimate seismic wave velocity at anomalous sites in Israel in order to calibrate a new attenuation equation for the Dead Sea region. Our new attenuation equation contains a term which quantifies only lithological effects, while factors such as building quality, foundation depth, topography, earthquake directivity, type of fault, etc. remain out of our scope. Nonetheless, about 60 % of the measured anomalous sites fit expectations; therefore, this new ground-motion prediction equation (GMPE) is statistically better than the old ones. From our local point of view, this is the first time that integration of the 1927 historical data and modern shear-wave velocity profile measurements improved the attenuation equation (sometimes referred to as the attenuation relation) for the Dead Sea region. In the wider context, regions of low-to-moderate seismicity should use macroseismic earthquake data, together with modern measurements, in order to better estimate the peak ground acceleration or the seismic intensities to be caused by future earthquakes. This integration will conceivably lead to a better mitigation of damage from future earthquakes and should improve maps of seismic hazard.


2021 ◽  
pp. 875529302110010
Author(s):  
Sameer Ladak ◽  
Sheri Molnar ◽  
Samantha Palmer

Site characterization is a crucial component in assessing seismic hazard, typically involving in situ shear-wave velocity ( VS) depth profiling, and measurement of site amplification including site period. Noninvasive methods are ideal for soil sites and become challenging in terms of field logistics and interpretation in more complex geologic settings including rock sites. Multiple noninvasive active- and passive-seismic techniques are applied at 25 seismograph stations across Eastern Canada. It is typically assumed that these stations are installed on hard rock. We investigate which site characterization methods are suitable at rock sites as well as confirm the hard rock assumption by providing VS profiles. Active-source compression-wave refraction and surface wave array techniques consistently provide velocity measurements at rock sites; passive-source array testing is less consistent but it is our most suitable method in constraining the rock VS. Bayesian inversion of Rayleigh wave dispersion curves provides quantitative uncertainty in the rock VS. We succeed in estimating rock VS at 16 stations, with constrained rock VS estimates at 7 stations that are consistent with previous estimates for Precambrian and Paleozoic rock types. The National Building Code of Canada uses solely the time-averaged shear-wave velocity of the upper 30 m ( VS30) to classify rock sites. We determine a mean VS30 of ∼ 1600 m/s for 16 Eastern Canada stations; the hard rock assumption is correct (>1500 m/s) but not as hard as often assumed (∼2000 m/s). Mean variability in VS30 is ∼400 m/s and can lead to softer rock classifications, in particular, for Paleozoic rock types with lower average rock VS near the hard/soft rock boundary. Microtremor and earthquake horizontal-to-vertical spectral ratios are obtained and provide site period classifications as an alternative to VS30.


2021 ◽  
Vol 19 (6) ◽  
pp. 2343-2370
Author(s):  
Federico Passeri ◽  
Cesare Comina ◽  
Sebastiano Foti ◽  
Laura Valentina Socco

AbstractThe compilation and maintenance of experimental databases are of crucial importance in all research fields, allowing for researchers to develop and test new methodologies. In this work, we present a flat-file database of experimental dispersion curves and shear wave velocity profiles, mainly from active surface wave testing, but including also data from passive surface wave testing and invasive methods. The Polito Surface Wave flat-file Database (PSWD) is a gathering of experimental measurements collected within the past 25 years at different Italian sites. Discussion on the database content is reported in this paper to evaluate some statistical properties of surface wave test results. Comparisons with other methods for shear wave velocity measurements are also considered. The main novelty of this work is the homogeneity of the PSWD in terms of processing and interpretation methods. A common processing strategy and a new inversion approach were applied to all the data in the PSWD to guarantee consistency. The PSWD can be useful for further correlation studies and is made available as a reference benchmark for the validation and verification of novel interpretation procedures by other researchers.


2014 ◽  
Vol 635-637 ◽  
pp. 750-754
Author(s):  
Peng Hu ◽  
Qing Li ◽  
Yi Wei Xu ◽  
Nan Ying Shentu ◽  
Quan Yuan Peng

Expound the importance of soil shear strength measurement at mudslide hidden point to release the loss caused by the disaster, explain the relationship between shear wave velocity, moisture content and shear strength, design the shear strength monitoring system combining the shear wave velocity measured by Piezoelectric bender elements and moisture content.


Sign in / Sign up

Export Citation Format

Share Document