P4409The relation between left atrial functions and ventilatory insufficiency during exercise in left heart disease: a stress echo/gas exchange analysis during exercise

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
T Sugimoto ◽  
F Bandera ◽  
G Generati ◽  
E Alfonzetti ◽  
V Tufaro ◽  
...  
Keyword(s):  
Heart Disease ◽  
Gas Exchange ◽  
Left Atrial ◽  
Left Heart ◽  
Left Heart Disease ◽  
Stress Echo ◽  
Ventilatory Insufficiency ◽  
Atrial Functions ◽  
Gas Exchange Analysis

scholarly journals Hemodynamics of the diastolic pressure gradients in acute heart failure: implications for the diagnosis of pre-capillary pulmonary hypertension in left heart disease

2018 ◽  
Vol 9 (1) ◽  
pp. 204589401881543 ◽  
Author(s):  
Doron Aronson ◽  
Emilia Hardak ◽  
Andrew J. Burger
Keyword(s):  
Heart Failure ◽  
Heart Disease ◽  
Acute Heart Failure ◽  
Left Atrial ◽  
Diastolic Pressure ◽  
Atrial Pressure ◽  
Left Atrial Pressure ◽  
Left Heart ◽  
Left Heart Disease ◽  
Pulmonary Capillary

The diastolic pressure gradient (DPG) has been proposed as the metric of choice for the diagnosis of pulmonary vascular changes in left heart disease. We tested the hypothesis that this metric is less sensitive to changes in left atrial pressure and stroke volume (SV) than the transpulmonary gradient (TPG). We studied the effect of dynamic changes in pulmonary capillary wedge pressure (PCWP), SV, and pulmonary artery capacitance (PAC) on DPG and TPG in 242 patients with acute heart failure undergoing decongestive therapy with continuous hemodynamic monitoring. There was a close impact of PCWP reduction on TPG and DPG, with a 0.13 mmHg (95% confidence interval [CI] 0.07–0.19, P < 0.0001) and 0.21 mmHg (95% CI 0.16–0.25, P < 0.0001) increase for every 1 mmHg decrease in PCWP, respectively. Changes in SV had a negligible effect on TPG and DPG (0.19 and 0.13 mmHg increase, respectively, for every 10-mL increase in SV). Heart rate was positively associated with DPG (0.41-mmHg increase per 10 BPM [95% CI 0.22–0.60, P < 0.0001]). The resistance-compliance product was positively associated with both TPG and DPG (2.65 mmHg [95% CI 2.47–2.83] and 1.94 mmHg [95% CI 1.80–2.08] for each 0.1-s increase, respectively). In conclusion, DPG is not less sensitive to changes in left atrial pressure and SV compared with TPG. Although DPG was not affected by changes in PAC, the concomitant increase in the resistance-compliance product increases DPG.

scholarly journals CT derived left atrial size identifies left heart disease in suspected pulmonary hypertension: Derivation and validation of predictive thresholds

2018 ◽  
Vol 260 ◽  
pp. 172-177 ◽  
Author(s):  
Benjamin J. Currie ◽  
Chris Johns ◽  
Matthew Chin ◽  
Thanos Charalampopolous ◽  
Charlie A. Elliot ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Heart Disease ◽  
Left Atrial ◽  
Left Heart ◽  
Left Atrial Size ◽  
Left Heart Disease ◽  
Atrial Size

Left Atrial Volume as an Indicator of Left Heart Disease in Patients with Pulmonary Hypertension

2007 ◽  
Vol 16 ◽  
pp. S56-S57
Author(s):  
W.P. Abhayaratna ◽  
J.G. Murphy ◽  
S.A. Ness ◽  
K. Abhayaratna ◽  
M.E. Barnes ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Heart Disease ◽  
Left Atrial ◽  
Left Atrial Volume ◽  
Left Heart ◽  
Atrial Volume ◽  
Left Heart Disease
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