scholarly journals 1345Prognostic impacts of impaired coronary vasodilatation and enhanced coronary vasoconstricting responses in patients with angina and unobstructive coronary arteries

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
A Suda ◽  
J Takahashi ◽  
K Hao ◽  
Y Kikuchi ◽  
T Shindo ◽  
...  
Keyword(s):  
Coronary Arteries ◽  
Coronary Vasodilatation

Cardamist - a glyceryl trinitrate aerosol

1967 ◽  
Vol 5 (2) ◽  
pp. 8-8
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Glyceryl Trinitrate ◽  
Coronary Arteries ◽  
Sublingual Administration ◽  
Vascular Bed ◽  
Anginal Pain ◽  
Coronary Vasodilatation ◽  
Local Accumulation

Glyceryl trinitrate is the best drug for preventing anginal pain.1 It is often assumed to dilate coronary arteries, but measurements of myocardial blood flow in man have failed to show that sublingual administration of the drug increases flow in patients with diseased coronary arteries.2 Local accumulation of metabolites during angina is believed to cause coronary vasodilatation: whether any drug can cause further local vasodilatation is uncertain. However, dilatation of the vascular bed may occur when the drug is injected into the coronary arteries of patients with ischaemic heart disease.3 The drug lowers arterial pressure both at rest and during exercise and it diminishes cardiac oxygen consumption. Thus it may help by reducing the metabolic requirements of the heart.1

scholarly journals Myocardial Infarction in a Premenopausal Woman on Leuprolide Therapy

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Irving E. Perez ◽  
Mark A. Menegus ◽  
Cynthia C. Taub
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Case Report ◽  
Chest Pain ◽  
Coronary Arteries ◽  
Coronary Flow ◽  
Premenopausal Women ◽  
Pain Syndrome ◽  
Coronary Vasodilatation ◽  
Chest Pain Syndrome

Premenopausal women with chest pain syndrome may have nonatherosclerotic coronary arteries with abnormal coronary flow. Estrogens have cardioprotective effect improving coronary vasodilatation. This case report discusses the consequences of leuprolide use by decreasing estrogen levels which led to acute myocardial infarction.

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